Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_061182                                                              18    1135
NP_001123509                                                           18    1135
NP_001013433                                                           18    1935
NP_060785                                                              18    1935
NP_361014                                                              18    1935
NP_116195                                                              17    4312
NP_057306                                                              17    4312
XP_006714933                                                           17    4312
XP_006714215                                                           17    4312
XP_006714214                                                           17    4312
XP_005262915                                                           17    4312
XP_006713424                                                           17    4312
XP_005265572                                                           17    4312
NP_039227                                                              17    4312
NP_039228                                                              17    4312
NP_001004466                                                           17    4312
NP_055806                                                              17    4312
NP_001004465                                                           17    4312
NP_001265426                                                           16    5631
NP_001265429                                                           16    5631
NP_001265427                                                           16    5631
NP_000666                                                              16    5631
NP_001265428                                                           16    5631
NP_009155                                                              16    5631
NP_000005                                                              16    5631
XP_006726604                                                           16    5631
XP_006726603                                                           16    5631
XP_006725215                                                           16    5631
XP_006719240                                                           16    5631
XP_006719237                                                           16    5631
XP_006719119                                                           16    5631
NP_694574                                                              16    7355
NP_683692                                                              16    7355
NP_005217                                                              16    7355
XP_005256319                                                           16    7355
XP_006721414                                                           16    7355
XP_005248208                                                           16    7355
XP_005248207                                                           16    7355
XP_006714021                                                           16    7355
NP_775882                                                              15    9605
NP_001261                                                              15    9605
NP_002855                                                              15    9605
NP_001819                                                              15    9605
NP_001307                                                              15    9605
XP_006726852                                                           15    9605
XP_006723594                                                           15    9605
XP_005271924                                                           15    9605
XP_005271923                                                           15    9605
XP_006710109                                                           15    9605
NP_076423                                                              15    9605
NP_001001968                                                           15    9605
>NP_061182
          Length = 334

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L YN+LVSG
Sbjct: 246 LAYNLLVSG 254
>NP_001123509
          Length = 326

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L YN+LVSG
Sbjct: 238 LAYNLLVSG 246
>NP_001013433
          Length = 589

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           LK NILVSG
Sbjct: 471 LKDNILVSG 479
>NP_060785
          Length = 627

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           LK NILVSG
Sbjct: 509 LKDNILVSG 517
>NP_361014
          Length = 707

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           LK NILVSG
Sbjct: 589 LKDNILVSG 597
>NP_116195
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           K NILVSG
Sbjct: 254 KANILVSG 261
>NP_057306
          Length = 622

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           KY+ILV G
Sbjct: 166 KYHILVEG 173
>XP_006714933
          Length = 496

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KYNILVSG 9
          KY+ILV G
Sbjct: 40 KYHILVEG 47
>XP_006714215
          Length = 3544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LKYNILVSG 9
            L Y+I+VSG
Sbjct: 3155 LAYHIIVSG 3163
>XP_006714214
          Length = 3544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LKYNILVSG 9
            L Y+I+VSG
Sbjct: 3155 LAYHIIVSG 3163
>XP_005262915
          Length = 3544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LKYNILVSG 9
            L Y+I+VSG
Sbjct: 3155 LAYHIIVSG 3163
>XP_006713424
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           K NILVSG
Sbjct: 254 KANILVSG 261
>XP_005265572
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           K NILVSG
Sbjct: 254 KANILVSG 261
>NP_039227
          Length = 315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           L+YN+L+S
Sbjct: 130 LRYNVLMS 137
>NP_039228
          Length = 318

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           L+YN+L+S
Sbjct: 130 LRYNVLMS 137
>NP_001004466
          Length = 315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           L+YN+L+S
Sbjct: 130 LRYNVLMS 137
>NP_055806
          Length = 3526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LKYNILVSG 9
            L Y+I+VSG
Sbjct: 3137 LAYHIIVSG 3145
>NP_001004465
          Length = 316

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           L+YN+L+S
Sbjct: 131 LRYNVLMS 138
>NP_001265426
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+YN LV+G
Sbjct: 110 LRYNGLVTG 118
>NP_001265429
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+YN LV+G
Sbjct: 110 LRYNGLVTG 118
>NP_001265427
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+YN LV+G
Sbjct: 110 LRYNGLVTG 118
>NP_000666
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+YN LV+G
Sbjct: 110 LRYNGLVTG 118
>NP_001265428
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+YN LV+G
Sbjct: 110 LRYNGLVTG 118
>NP_009155
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LKYNILVSG 9
           LK+++LV+G
Sbjct: 118 LKFSLLVTG 126
>NP_000005
          Length = 1474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LKYNIL 6
            LKYNIL
Sbjct: 1328 LKYNIL 1333
>XP_006726604
          Length = 232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKYNILV 7
           LKYN+L+
Sbjct: 107 LKYNVLL 113
>XP_006726603
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LKYNILV 7
            LKYN+L+
Sbjct: 1125 LKYNVLL 1131
>XP_006725215
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LKYNILV 7
            LKYN+L+
Sbjct: 1125 LKYNVLL 1131
>XP_006719240
          Length = 113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKYNILV 7
          LKYN+L+
Sbjct: 21 LKYNVLL 27
>XP_006719237
          Length = 1263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LKYNILV 7
            LKYN+L+
Sbjct: 1124 LKYNVLL 1130
>XP_006719119
          Length = 1512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LKYNIL 6
            LKYNIL
Sbjct: 1328 LKYNIL 1333
>NP_694574
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           ++YNILV+
Sbjct: 345 MEYNILVN 352
>NP_683692
          Length = 3051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    YNILVSG 9
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>NP_005217
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           K NIL+SG
Sbjct: 93  KVNILMSG 100
>XP_005256319
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           ++YNILV+
Sbjct: 345 MEYNILVN 352
>XP_006721414
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           ++YNILV+
Sbjct: 259 MEYNILVN 266
>XP_005248208
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    YNILVSG 9
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_005248207
          Length = 3098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    YNILVSG 9
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_006714021
          Length = 3112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    YNILVSG 9
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>NP_775882
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YNILVSG 9
           Y++L+SG
Sbjct: 95  YSVLISG 101
>NP_001261
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           LK+NIL++
Sbjct: 584 LKFNILLT 591
>NP_002855
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LKYNIL 6
            +KYNIL
Sbjct: 1334 MKYNIL 1339
>NP_001819
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KYNILVSG 9
           KY ++V+G
Sbjct: 99  KYQVMVNG 106
>NP_001307
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           +KY++LVS
Sbjct: 308 VKYDLLVS 315
>XP_006726852
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKYNILVSG 9
          + YN+ VSG
Sbjct: 60 IDYNVEVSG 68
>XP_006723594
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKYNILVSG 9
          + YN+ VSG
Sbjct: 60 IDYNVEVSG 68
>XP_005271924
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           LK+NIL++
Sbjct: 584 LKFNILLT 591
>XP_005271923
          Length = 1798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKYNILVS 8
           LK+NIL++
Sbjct: 584 LKFNILLT 591
>XP_006710109
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKYNILVSG 9
          + YN+ VSG
Sbjct: 60 IDYNVEVSG 68
>NP_076423
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           +K N+LV+G
Sbjct: 169 VKKNVLVTG 177
>NP_001001968
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYNILVSG 9
           L+Y +L+SG
Sbjct: 132 LRYPLLMSG 140
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.145    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,170
Number of extensions: 812
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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