Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1135
XP_005266703                                                           18    1135
NP_001139281                                                           17    3301
NP_001074008                                                           17    3301
NP_001070654                                                           17    3301
NP_079005                                                              17    3301
XP_006723449                                                           17    3301
NP_004035                                                              17    4312
XP_006712608                                                           17    4312
NP_003625                                                              16    5631
NP_001189431                                                           16    5631
NP_940862                                                              16    5631
NP_659547                                                              16    5631
NP_005925                                                              16    5631
XP_005261846                                                           16    5631
XP_005259618                                                           16    5631
XP_005255220                                                           16    5631
XP_006721086                                                           16    5631
XP_006714287                                                           16    5631
XP_006714286                                                           16    5631
XP_005263076                                                           16    5631
XP_005270606                                                           16    5631
XP_006710456                                                           16    5631
NP_001107829                                                           16    5631
NP_001258463                                                           16    7355
NP_001380                                                              16    7355
NP_115609                                                              16    7355
XP_006724038                                                           16    7355
XP_005268184                                                           16    7355
XP_005268183                                                           16    7355
NP_055444                                                              15    9605
NP_113584                                                              15    9605
NP_689681                                                              15    9605
NP_076919                                                              15    9605
XP_006725174                                                           15    9605
XP_006725173                                                           15    9605
XP_006725172                                                           15    9605
XP_006725171                                                           15    9605
XP_006725170                                                           15    9605
XP_006725169                                                           15    9605
XP_006725168                                                           15    9605
XP_006725167                                                           15    9605
XP_005262029                                                           15    9605
XP_005262028                                                           15    9605
XP_005262026                                                           15    9605
XP_006724637                                                           15    9605
XP_005262025                                                           15    9605
XP_005262024                                                           15    9605
XP_005262023                                                           15    9605
XP_005262022                                                           15    9605
XP_006721789                                                           15    9605
XP_006721788                                                           15    9605
XP_005266099                                                           15    9605
XP_006716304                                                           15    9605
XP_006716303                                                           15    9605
XP_006716302                                                           15    9605
XP_005266098                                                           15    9605
XP_005266097                                                           15    9605
XP_005266096                                                           15    9605
XP_006716301                                                           15    9605
NP_065954                                                              15    9605
>NP_443179
          Length = 2170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           LKYEQS SE
Sbjct: 737 LKYEQSISE 745
>XP_005266703
          Length = 1501

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          LKYEQS SE
Sbjct: 68 LKYEQSISE 76
>NP_001139281
          Length = 2036

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LKYEQSNSE 9
            L+ EQSNSE
Sbjct: 1803 LEEEQSNSE 1811
>NP_001074008
          Length = 1101

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KY Q+NSE
Sbjct: 598 KYAQANSE 605
>NP_001070654
          Length = 2003

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LKYEQSNSE 9
            L+ EQSNSE
Sbjct: 1770 LEEEQSNSE 1778
>NP_079005
          Length = 1995

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LKYEQSNSE 9
            L+ EQSNSE
Sbjct: 1762 LEEEQSNSE 1770
>XP_006723449
          Length = 2003

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LKYEQSNSE 9
            L+ EQSNSE
Sbjct: 1770 LEEEQSNSE 1778
>NP_004035
          Length = 592

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKYEQSNS 8
           +KY QSNS
Sbjct: 425 VKYTQSNS 432
>XP_006712608
          Length = 533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKYEQSNS 8
           +KY QSNS
Sbjct: 366 VKYTQSNS 373
>NP_003625
          Length = 284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKYEQSNSE 9
           +KY Q N E
Sbjct: 208 IKYRQENQE 216
>NP_001189431
          Length = 264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKYEQSNSE 9
           +KY Q N E
Sbjct: 188 IKYRQENQE 196
>NP_940862
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KYE+ N+E
Sbjct: 567 KYEEMNAE 574
>NP_659547
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KY QSN+E
Sbjct: 218 KYFQSNAE 225
>NP_005925
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           L+ E+SNSE
Sbjct: 354 LEVEESNSE 362
>XP_005261846
          Length = 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKYEQSNSE 9
           +KY Q N E
Sbjct: 184 IKYRQENQE 192
>XP_005259618
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           L+ E+SNSE
Sbjct: 312 LEVEESNSE 320
>XP_005255220
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KY QSN+E
Sbjct: 218 KYFQSNAE 225
>XP_006721086
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KY QSN+E
Sbjct: 218 KYFQSNAE 225
>XP_006714287
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           LKY+++N E
Sbjct: 175 LKYKKANEE 183
>XP_006714286
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           LKY+++N E
Sbjct: 175 LKYKKANEE 183
>XP_005263076
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           LKY+++N E
Sbjct: 175 LKYKKANEE 183
>XP_005270606
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KYE+ N+E
Sbjct: 437 KYEEMNAE 444
>XP_006710456
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KYEQSNSE 9
           KYE+ N+E
Sbjct: 567 KYEEMNAE 574
>NP_001107829
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKYEQSNSE 9
           LKY+++N E
Sbjct: 175 LKYKKANEE 183
>NP_001258463
          Length = 1994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKYEQSNSE 9
            L+Y + NSE
Sbjct: 1414 LQYSEDNSE 1422
>NP_001380
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKYEQSNSE 9
            L+Y + NSE
Sbjct: 1414 LQYSEDNSE 1422
>NP_115609
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KYEQSN 7
           KYE+SN
Sbjct: 501 KYEESN 506
>XP_006724038
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKYEQSNSE 9
            L+Y + NSE
Sbjct: 1309 LQYSEDNSE 1317
>XP_005268184
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KYEQSN 7
           KYE+SN
Sbjct: 402 KYEESN 407
>XP_005268183
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KYEQSN 7
           KYE+SN
Sbjct: 443 KYEESN 448
>NP_055444
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 16 MKYDTNNNE 24
>NP_113584
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>NP_689681
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   KYEQSNSE 9
           KY Q N E
Sbjct: 322 KYSQDNKE 329
>NP_076919
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  YEQSNS 8
          Y+QSNS
Sbjct: 58 YQQSNS 63
>XP_006725174
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 16 MKYDTNNNE 24
>XP_006725173
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006725172
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006725171
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006725170
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 16 MKYDTNNNE 24
>XP_006725169
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006725168
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006725167
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_005262029
          Length = 4240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_005262028
          Length = 4341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_005262026
          Length = 4359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_006724637
          Length = 4365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1599 KYLQSNS 1605
>XP_005262025
          Length = 4373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_005262024
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_005262023
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_005262022
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KYEQSNS 8
            KY QSNS
Sbjct: 1608 KYLQSNS 1614
>XP_006721789
          Length = 408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   KYEQSNSE 9
           KY Q N E
Sbjct: 322 KYSQDNKE 329
>XP_006721788
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   KYEQSNSE 9
           KY Q N E
Sbjct: 99  KYSQDNKE 106
>XP_005266099
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 16 MKYDTNNNE 24
>XP_006716304
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006716303
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006716302
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_005266098
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 16 MKYDTNNNE 24
>XP_005266097
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_005266096
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>XP_006716301
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LKYEQSNSE 9
          +KY+ +N+E
Sbjct: 40 MKYDTNNNE 48
>NP_065954
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LKYEQSN 7
           LKY QSN
Sbjct: 200 LKYIQSN 206
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.283    0.106    0.246 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 535,434
Number of extensions: 1009
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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