Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              20     390
NP_001087241                                                           20     390
XP_006714101                                                           20     390
XP_005265799                                                           20     390
XP_005265798                                                           20     390
XP_005265797                                                           20     390
NP_001229392                                                           17    4312
NP_001123357                                                           17    4312
XP_005260582                                                           16    5631
XP_006723932                                                           16    5631
XP_006723931                                                           16    5631
NP_001156001                                                           16    7355
NP_062832                                                              16    7355
NP_001074003                                                           16    7355
XP_005254452                                                           16    7355
XP_005254451                                                           16    7355
XP_005248806                                                           16    7355
XP_005248804                                                           16    7355
XP_005248803                                                           16    7355
XP_005248802                                                           16    7355
XP_005248801                                                           16    7355
XP_005248800                                                           16    7355
NP_006781                                                              15    9605
NP_001129412                                                           15    9605
NP_002438                                                              15    9605
NP_001231866                                                           15    9605
NP_001177255                                                           15    9605
NP_073557                                                              15    9605
NP_055750                                                              15    9605
NP_703152                                                              15    9605
NP_148978                                                              15    9605
NP_775885                                                              15    9605
NP_001004060                                                           15    9605
NP_001254824                                                           15    9605
NP_001004067                                                           15    9605
NP_597712                                                              15    9605
NP_006192                                                              15    9605
XP_006725258                                                           15    9605
XP_006724598                                                           15    9605
XP_006724597                                                           15    9605
XP_005272672                                                           15    9605
XP_005272671                                                           15    9605
XP_006724331                                                           15    9605
XP_005261390                                                           15    9605
XP_005261387                                                           15    9605
XP_005261386                                                           15    9605
XP_006724195                                                           15    9605
XP_005261385                                                           15    9605
XP_005255375                                                           15    9605
XP_006718533                                                           15    9605
XP_005272186                                                           15    9605
XP_005265227                                                           15    9605
XP_006711286                                                           15    9605
XP_005245025                                                           15    9605
XP_005245024                                                           15    9605
XP_006711285                                                           15    9605
XP_006711284                                                           15    9605
XP_006711283                                                           15    9605
XP_006711282                                                           15    9605
XP_006711281                                                           15    9605
XP_006711280                                                           15    9605
XP_006711279                                                           15    9605
XP_006711278                                                           15    9605
XP_006711277                                                           15    9605
XP_005245023                                                           15    9605
XP_006711276                                                           15    9605
XP_006711275                                                           15    9605
NP_001163931                                                           15    9605
NP_699189                                                              15    9605
NP_060698                                                              15    9605
NP_055102                                                              15    9605
>NP_000213
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>NP_001087241
          Length = 972

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>XP_006714101
          Length = 526

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>XP_005265799
          Length = 973

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>XP_005265798
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>XP_005265797
          Length = 977

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LKVRPAFK 8
           LKVRPAFK
Sbjct: 202 LKVRPAFK 209
>NP_001229392
          Length = 262

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VRPAFK 8
           VRPAFK
Sbjct: 123 VRPAFK 128
>NP_001123357
          Length = 179

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKVRPAFK 8
           L V+PAFK
Sbjct: 113 LHVKPAFK 120
>XP_005260582
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKVRPAFKV 9
          LKVRP  K+
Sbjct: 16 LKVRPTRKI 24
>XP_006723932
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKVRPAFKV 9
          LKVRP  K+
Sbjct: 16 LKVRPTRKI 24
>XP_006723931
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKVRPAFKV 9
          LKVRP  K+
Sbjct: 16 LKVRPTRKI 24
>NP_001156001
          Length = 1515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 457 LKVRPA 462
>NP_062832
          Length = 588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVRPAFKV 9
           L  RPAF+V
Sbjct: 233 LGTRPAFEV 241
>NP_001074003
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KVRPAFK 8
           ++RP+FK
Sbjct: 967 RIRPSFK 973
>XP_005254452
          Length = 2188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KVRPAFK 8
           ++RP+FK
Sbjct: 967 RIRPSFK 973
>XP_005254451
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KVRPAFK 8
           ++RP+FK
Sbjct: 967 RIRPSFK 973
>XP_005248806
          Length = 1317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 483 LKVRPA 488
>XP_005248804
          Length = 1378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 320 LKVRPA 325
>XP_005248803
          Length = 1455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 397 LKVRPA 402
>XP_005248802
          Length = 1515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 457 LKVRPA 462
>XP_005248801
          Length = 1541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 483 LKVRPA 488
>XP_005248800
          Length = 1541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKVRPA 6
           LKVRPA
Sbjct: 483 LKVRPA 488
>NP_006781
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           L+VRP F
Sbjct: 454 LRVRPTF 460
>NP_001129412
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           L+VRP F
Sbjct: 270 LRVRPTF 276
>NP_002438
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    VRPAFKV 9
            VRP F+V
Sbjct: 1330 VRPTFRV 1336
>NP_001231866
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    VRPAFKV 9
            VRP F+V
Sbjct: 1281 VRPTFRV 1287
>NP_001177255
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           LKVRP +
Sbjct: 524 LKVRPVY 530
>NP_073557
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           LKVRP +
Sbjct: 524 LKVRPVY 530
>NP_055750
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPA+KV
Sbjct: 856 RPAYKV 861
>NP_703152
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVRPAFKV 9
           L V+P FK+
Sbjct: 120 LNVQPDFKI 128
>NP_148978
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 492 RPAFRV 497
>NP_775885
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
>NP_001004060
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
>NP_001254824
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>NP_001004067
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
>NP_597712
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>NP_006192
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 486 RPAFRV 491
>XP_006725258
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
>XP_006724598
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 486 RPAFRV 491
>XP_006724597
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 486 RPAFRV 491
>XP_005272672
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 486 RPAFRV 491
>XP_005272671
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 533 RPAFRV 538
>XP_006724331
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           LKVRP +
Sbjct: 167 LKVRPVY 173
>XP_005261390
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>XP_005261387
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>XP_005261386
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>XP_006724195
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>XP_005261385
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRPAFKV 9
          VRP +KV
Sbjct: 77 VRPTYKV 83
>XP_005255375
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
>XP_006718533
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVRPAFKV 9
           L V+P FK+
Sbjct: 120 LNVQPDFKI 128
>XP_005272186
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           L+VRP F
Sbjct: 339 LRVRPTF 345
>XP_005265227
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    VRPAFKV 9
            VRP F+V
Sbjct: 1331 VRPTFRV 1337
>XP_006711286
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPA+KV
Sbjct: 829 RPAYKV 834
>XP_005245025
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPA+KV
Sbjct: 964 RPAYKV 969
>XP_005245024
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPA+KV
Sbjct: 985 RPAYKV 990
>XP_006711285
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1001 RPAYKV 1006
>XP_006711284
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1001 RPAYKV 1006
>XP_006711283
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1001 RPAYKV 1006
>XP_006711282
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1035 RPAYKV 1040
>XP_006711281
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1041 RPAYKV 1046
>XP_006711280
          Length = 1251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1059 RPAYKV 1064
>XP_006711279
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1062 RPAYKV 1067
>XP_006711278
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1064 RPAYKV 1069
>XP_006711277
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1109 RPAYKV 1114
>XP_005245023
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1089 RPAYKV 1094
>XP_006711276
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1091 RPAYKV 1096
>XP_006711275
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RPAFKV 9
            RPA+KV
Sbjct: 1109 RPAYKV 1114
>NP_001163931
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 560 RPAFRV 565
>NP_699189
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RPAFKV 9
           RPAF+V
Sbjct: 340 RPAFRV 345
>NP_060698
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LKVRPAF 7
           LK+RP F
Sbjct: 196 LKIRPYF 202
>NP_055102
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVRPAFKV 9
           LK+ P F V
Sbjct: 318 LKIEPVFHV 326
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.146    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 584,732
Number of extensions: 755
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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