Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006726390                                                           17    4312
XP_006726389                                                           17    4312
XP_006726388                                                           17    4312
XP_006726387                                                           17    4312
XP_006712967                                                           17    4312
XP_006711142                                                           17    4312
XP_006711141                                                           17    4312
XP_006711140                                                           17    4312
XP_006710131                                                           17    4312
XP_006710130                                                           17    4312
XP_006710129                                                           17    4312
XP_006710128                                                           17    4312
NP_149162                                                              16    7355
NP_001835                                                              16    7355
NP_037418                                                              16    7355
NP_001127891                                                           16    7355
NP_055897                                                              16    7355
NP_065073                                                              16    7355
XP_006719305                                                           16    7355
XP_006717893                                                           16    7355
XP_006717891                                                           16    7355
XP_006717890                                                           16    7355
XP_005269849                                                           16    7355
XP_006717888                                                           16    7355
XP_006717887                                                           16    7355
XP_006717886                                                           16    7355
XP_006717885                                                           16    7355
XP_006717884                                                           16    7355
XP_005269836                                                           16    7355
XP_006715582                                                           16    7355
XP_005271302                                                           16    7355
XP_005271301                                                           16    7355
XP_005271298                                                           16    7355
NP_001127892                                                           16    7355
NP_003494                                                              16    7355
NP_004632                                                              15    9605
NP_001182555                                                           15    9605
NP_055654                                                              15    9605
NP_001159724                                                           15    9605
NP_001186170                                                           15    9605
NP_001153399                                                           15    9605
NP_996985                                                              15    9605
NP_001153401                                                           15    9605
NP_005928                                                              15    9605
NP_003928                                                              15    9605
NP_659407                                                              15    9605
XP_006725391                                                           15    9605
XP_006725389                                                           15    9605
XP_006725388                                                           15    9605
XP_006725387                                                           15    9605
XP_006724591                                                           15    9605
XP_006724590                                                           15    9605
XP_006724589                                                           15    9605
XP_005272646                                                           15    9605
XP_005257438                                                           15    9605
XP_006721974                                                           15    9605
XP_006721973                                                           15    9605
XP_005257436                                                           15    9605
XP_005252669                                                           15    9605
XP_006717572                                                           15    9605
XP_005252667                                                           15    9605
XP_005252666                                                           15    9605
XP_005252665                                                           15    9605
XP_005252663                                                           15    9605
XP_005252662                                                           15    9605
NP_071414                                                              15    9605
NP_001028170                                                           15    9605
>XP_006726390
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006726389
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006726388
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006726387
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006712967
          Length = 298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AARLRC
Sbjct: 29 AARLRC 34
>XP_006711142
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006711141
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006711140
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006710131
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006710130
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006710129
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>XP_006710128
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AARLRC 9
           AARLRC
Sbjct: 251 AARLRC 256
>NP_149162
          Length = 1418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LKVAARLRC 9
          L VAA LRC
Sbjct: 15 LLVAAVLRC 23
>NP_001835
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LKVAARLRC 9
          L VAA LRC
Sbjct: 15 LLVAAVLRC 23
>NP_037418
          Length = 890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LK+A RLR
Sbjct: 763 LKIAQRLR 770
>NP_001127891
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>NP_055897
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VAARLRC 9
           VAA LRC
Sbjct: 356 VAASLRC 362
>NP_065073
          Length = 2177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVAARLRC 9
           L+ AARL C
Sbjct: 918 LRKAARLSC 926
>XP_006719305
          Length = 1488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LKVAARLRC 9
          L VAA LRC
Sbjct: 15 LLVAAVLRC 23
>XP_006717893
          Length = 1233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 698 LKVAARSR 705
>XP_006717891
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 607 LKVAARSR 614
>XP_006717890
          Length = 1145

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 609 LKVAARSR 616
>XP_005269849
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 698 LKVAARSR 705
>XP_006717888
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 702 LKVAARSR 709
>XP_006717887
          Length = 1211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 702 LKVAARSR 709
>XP_006717886
          Length = 1234

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 698 LKVAARSR 705
>XP_006717885
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 702 LKVAARSR 709
>XP_006717884
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 702 LKVAARSR 709
>XP_005269836
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LKVAARLR 8
           LKVAAR R
Sbjct: 702 LKVAARSR 709
>XP_006715582
          Length = 2106

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVAARLRC 9
           L+ AARL C
Sbjct: 847 LRKAARLSC 855
>XP_005271302
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>XP_005271301
          Length = 542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>XP_005271298
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>NP_001127892
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>NP_003494
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKVAARLRC 9
           +++AA L+C
Sbjct: 99  IRIAAELQC 107
>NP_004632
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>NP_001182555
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>NP_055654
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKVAARLRC 9
          L+ AARL C
Sbjct: 23 LEEAARLSC 31
>NP_001159724
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKVAARLRC 9
          L+ AARL C
Sbjct: 23 LEEAARLSC 31
>NP_001186170
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AA L+C
Sbjct: 15 RIAAELKC 22
>NP_001153399
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KVAARLRC 9
           +VAA L+C
Sbjct: 266 QVAAHLKC 273
>NP_996985
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KVAARLRC 9
           +VAA L+C
Sbjct: 336 QVAAHLKC 343
>NP_001153401
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KVAARLRC 9
           +VAA L+C
Sbjct: 317 QVAAHLKC 324
>NP_005928
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>NP_003928
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AA L+C
Sbjct: 15 RIAAELKC 22
>NP_659407
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AARL C
Sbjct: 5  ELAARLNC 12
>XP_006725391
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006725389
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006725388
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006725387
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006724591
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AARL C
Sbjct: 5  ELAARLNC 12
>XP_006724590
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AARL C
Sbjct: 56 ELAARLNC 63
>XP_006724589
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AARL C
Sbjct: 56 ELAARLNC 63
>XP_005272646
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AARL C
Sbjct: 56 ELAARLNC 63
>XP_005257438
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006721974
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_006721973
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_005257436
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 60 AARVRC 65
>XP_005252669
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_006717572
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_005252667
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_005252666
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_005252665
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_005252663
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>XP_005252662
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AARLRC 9
          AAR+RC
Sbjct: 77 AARVRC 82
>NP_071414
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKVAARLRC 9
           LKV+++++C
Sbjct: 601 LKVSSKVQC 609
>NP_001028170
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  KVAARLRC 9
          ++AA L+C
Sbjct: 15 RIAAELKC 22
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.142    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,768
Number of extensions: 405
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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