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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_997464                                                              17    3301
NP_001139320                                                           16    5631
NP_001139321                                                           16    5631
NP_001139323                                                           16    5631
NP_006008                                                              16    5631
NP_001139322                                                           16    5631
NP_001139324                                                           16    5631
NP_001139319                                                           16    5631
XP_006726646                                                           16    5631
XP_006714037                                                           16    5631
XP_005248253                                                           16    5631
XP_005248252                                                           16    5631
XP_006714036                                                           16    5631
NP_001065                                                              16    7355
NP_001274275                                                           16    7355
NP_055467                                                              16    7355
NP_001070913                                                           16    7355
NP_001130029                                                           16    7355
NP_001130030                                                           16    7355
NP_055685                                                              16    7355
NP_055550                                                              16    7355
NP_066962                                                              16    7355
XP_005265757                                                           16    7355
XP_003846672                                                           16    7355
NP_001077090                                                           16    7355
NP_066011                                                              16    7355
NP_060058                                                              15    9605
NP_438172                                                              15    9605
NP_542399                                                              15    9605
NP_663624                                                              15    9605
NP_060453                                                              15    9605
XP_005257554                                                           15    9605
XP_005272220                                                           15    9605
XP_006715117                                                           15    9605
XP_006715116                                                           15    9605
XP_006715115                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLLDETA 9
           LKTL+DETA
Sbjct: 303 LKTLVDETA 311



>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLLDETA 9
           LKTL+DETA
Sbjct: 98  LKTLVDETA 106



>NP_997464
          Length = 320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LKTLLDETA 9
           L+TLLD++A
Sbjct: 278 LRTLLDQSA 286



>NP_001139320
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>NP_001139321
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 201 LRTLLNET 208



>NP_001139323
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>NP_006008
          Length = 865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 201 LRTLLNET 208



>NP_001139322
          Length = 834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 201 LRTLLNET 208



>NP_001139324
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>NP_001139319
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>XP_006726646
          Length = 453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KTLLDETA 9
          KTLL+E+A
Sbjct: 19 KTLLEESA 26




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KTLLDETA 9
           KTLL+E+A
Sbjct: 161 KTLLEESA 168



>XP_006714037
          Length = 787

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 123 LRTLLNET 130



>XP_005248253
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>XP_005248252
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>XP_006714036
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKTLLDET 8
           L+TLL+ET
Sbjct: 192 LRTLLNET 199



>NP_001065
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKTLLDE 7
          +KT+LDE
Sbjct: 39 IKTILDE 45



>NP_001274275
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKTLLDETA 9
           L  LLDETA
Sbjct: 289 LYQLLDETA 297



>NP_055467
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKTLLDETA 9
           +KTLLD+ A
Sbjct: 713 VKTLLDDFA 721



>NP_001070913
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKTLLDE 7
           +KT+LDE
Sbjct: 346 MKTILDE 352



>NP_001130029
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKTLLDETA 9
           L  LLDETA
Sbjct: 526 LYQLLDETA 534



>NP_001130030
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKTLLDETA 9
           L  LLDETA
Sbjct: 497 LYQLLDETA 505



>NP_055685
          Length = 1239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KTLLDET 8
          KTLLD T
Sbjct: 50 KTLLDNT 56



>NP_055550
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKTLLDE 7
           +KT+LDE
Sbjct: 346 MKTILDE 352



>NP_066962
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKTLLDE 7
          +KT+LDE
Sbjct: 39 IKTILDE 45



>XP_005265757
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKTLLDE 7
          +KT+LDE
Sbjct: 39 IKTILDE 45



>XP_003846672
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKTLLDETA 9
           +KTLLD+ A
Sbjct: 713 VKTLLDDFA 721



>NP_001077090
          Length = 1239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KTLLDET 8
          KTLLD T
Sbjct: 50 KTLLDNT 56



>NP_066011
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKTLLDETA 9
           L  LLDETA
Sbjct: 478 LYQLLDETA 486



>NP_060058
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKTLLDE 7
           LKTL+D+
Sbjct: 206 LKTLIDD 212



>NP_438172
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKTLLDE 7
           LKTL+D+
Sbjct: 206 LKTLIDD 212



>NP_542399
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKTLLDETA 9
           LKT LDE A
Sbjct: 226 LKTELDEWA 234



>NP_663624
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKTLLDE 7
          LKT LDE
Sbjct: 65 LKTTLDE 71



>NP_060453
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LKTLLD 6
           LKTLLD
Sbjct: 132 LKTLLD 137



>XP_005257554
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LKTLLD 6
          LKTLLD
Sbjct: 50 LKTLLD 55



>XP_005272220
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKTLLDE 7
           LKTL+D+
Sbjct: 206 LKTLIDD 212



>XP_006715117
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKTLLDE 7
          LKT LDE
Sbjct: 65 LKTTLDE 71



>XP_006715116
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKTLLDE 7
          LKT LDE
Sbjct: 65 LKTTLDE 71



>XP_006715115
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKTLLDE 7
          LKT LDE
Sbjct: 65 LKTTLDE 71



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.127    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 484,266
Number of extensions: 806
Number of successful extensions: 39
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)