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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    4312
XP_006716142                                                           17    4312
XP_005250088                                                           17    4312
XP_006716141                                                           17    4312
XP_005250085                                                           17    4312
XP_006716140                                                           17    4312
XP_005250084                                                           17    4312
XP_005250083                                                           17    4312
XP_005250082                                                           17    4312
NP_055244                                                              16    5631
NP_002967                                                              16    5631
XP_005247419                                                           16    5631
XP_006712745                                                           16    5631
XP_006712744                                                           16    5631
XP_006712743                                                           16    5631
NP_062815                                                              15    9605
NP_001137140                                                           15    9605
NP_862830                                                              15    9605
NP_001245215                                                           15    9605
NP_055680                                                              15    9605
NP_057129                                                              15    9605
NP_001269358                                                           15    9605
NP_001245216                                                           15    9605
NP_775785                                                              15    9605
XP_005268894                                                           15    9605
XP_006714605                                                           15    9605
XP_006714604                                                           15    9605
XP_006714603                                                           15    9605
XP_006714602                                                           15    9605
XP_006714601                                                           15    9605
XP_006714600                                                           15    9605

>NP_733751
          Length = 4911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 912 LKSGIGAVV 920



>XP_006716142
          Length = 4927

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_005250088
          Length = 4928

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_006716141
          Length = 4959

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_005250085
          Length = 4979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_006716140
          Length = 4982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_005250084
          Length = 4982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>XP_005250083
          Length = 4982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 912 LKSGIGAVV 920



>XP_005250082
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKS IGAVV
Sbjct: 913 LKSGIGAVV 921



>NP_055244
          Length = 984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+GA V
Sbjct: 389 LKSLLGAGV 397



>NP_002967
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+G ++
Sbjct: 223 LKSLVGVLI 231



>XP_005247419
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+GA V
Sbjct: 389 LKSLLGAGV 397



>XP_006712745
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+G ++
Sbjct: 223 LKSLVGVLI 231



>XP_006712744
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+G ++
Sbjct: 223 LKSLVGVLI 231



>XP_006712743
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           LKSL+G ++
Sbjct: 223 LKSLVGVLI 231



>NP_062815
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L S++GAV+
Sbjct: 390 LVSIVGAVI 398



>NP_001137140
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LKSLIGAVV 9
          L +L+GAVV
Sbjct: 8  LPTLLGAVV 16



>NP_862830
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LKSLIGAVV 9
          L +L+GAVV
Sbjct: 8  LPTLLGAVV 16



>NP_001245215
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 143 LVSLIGAMI 151



>NP_055680
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           +KS++G +V
Sbjct: 271 MKSIVGEIV 279



>NP_057129
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LKSLIGA 7
          +KSLIGA
Sbjct: 65 VKSLIGA 71



>NP_001269358
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LKSLIGAVV 9
          L SLIGA++
Sbjct: 82 LVSLIGAMI 90



>NP_001245216
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 179 LVSLIGAMI 187



>NP_775785
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_005268894
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LKSLIGAVV 9
          L +L+GAVV
Sbjct: 8  LPTLLGAVV 16



>XP_006714605
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_006714604
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_006714603
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_006714602
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_006714601
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



>XP_006714600
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKSLIGAVV 9
           L SLIGA++
Sbjct: 206 LVSLIGAMI 214



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.144    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 310,603
Number of extensions: 329
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)