Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     869
NP_001095896                                                           17    2528
NP_079437                                                              17    2528
NP_001271200                                                           17    2528
NP_006819                                                              17    2528
XP_006722175                                                           17    2528
XP_006722174                                                           17    2528
XP_006715385                                                           17    2528
XP_005263921                                                           17    2528
XP_005263920                                                           17    2528
XP_005263919                                                           17    2528
NP_058544                                                              17    4312
NP_001030017                                                           17    4312
NP_001189788                                                           17    4312
NP_001123513                                                           17    4312
NP_003020                                                              17    4312
NP_001123512                                                           17    4312
NP_892113                                                              17    4312
XP_005252109                                                           17    4312
XP_005245508                                                           17    4312
XP_005245506                                                           17    4312
NP_064695                                                              16    5631
NP_056533                                                              16    5631
NP_001074007                                                           16    5631
XP_006726603                                                           16    5631
XP_006725215                                                           16    5631
XP_006725015                                                           16    5631
XP_006719237                                                           16    5631
XP_005250563                                                           16    5631
XP_005250422                                                           16    5631
XP_005250421                                                           16    5631
XP_005244875                                                           16    5631
NP_001255213                                                           16    7355
NP_542166                                                              16    7355
NP_056357                                                              16    7355
NP_079337                                                              16    7355
XP_005272554                                                           16    7355
NP_001255214                                                           16    7355
NP_001120652                                                           15    9605
NP_000251                                                              15    9605
NP_001017423                                                           15    9605
NP_002851                                                              15    9605
NP_789792                                                              15    9605
NP_694691                                                              15    9605
NP_694690                                                              15    9605
NP_066576                                                              15    9605
NP_940870                                                              15    9605
XP_003960381                                                           15    9605
XP_005261866                                                           15    9605
XP_005261865                                                           15    9605
XP_005261864                                                           15    9605
XP_005261863                                                           15    9605
XP_005261862                                                           15    9605
XP_005261861                                                           15    9605
XP_005261860                                                           15    9605
XP_006718624                                                           15    9605
XP_005274069                                                           15    9605
XP_006718623                                                           15    9605
XP_006718622                                                           15    9605
XP_006718621                                                           15    9605
XP_006718281                                                           15    9605
XP_006717996                                                           15    9605
XP_006715495                                                           15    9605
XP_006715494                                                           15    9605
XP_006715493                                                           15    9605
XP_006713898                                                           15    9605
XP_003403469                                                           15    9605
XP_006713897                                                           15    9605
XP_006710216                                                           15    9605
XP_003403820                                                           15    9605
XP_006710215                                                           15    9605
NP_115536                                                              15    9605
>NP_115803
          Length = 1156

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           LKQIAAN Q
Sbjct: 436 LKQIAANRQ 444
>NP_001095896
          Length = 1140

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKQIAANH 8
           LKQ+ ANH
Sbjct: 391 LKQVHANH 398
>NP_079437
          Length = 881

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QI ANH+
Sbjct: 830 LRQIHANHE 838
>NP_001271200
          Length = 731

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+ A HQ
Sbjct: 709 LKQVKAGHQ 717
>NP_006819
          Length = 2202

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+ A HQ
Sbjct: 709 LKQVKAGHQ 717
>XP_006722175
          Length = 730

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QI ANH+
Sbjct: 679 LRQIHANHE 687
>XP_006722174
          Length = 743

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QI ANH+
Sbjct: 692 LRQIHANHE 700
>XP_006715385
          Length = 1866

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+ A HQ
Sbjct: 373 LKQVKAGHQ 381
>XP_005263921
          Length = 1147

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKQIAANH 8
           LKQ+ ANH
Sbjct: 398 LKQVHANH 405
>XP_005263920
          Length = 1155

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKQIAANH 8
           LKQ+ ANH
Sbjct: 406 LKQVHANH 413
>XP_005263919
          Length = 1162

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKQIAANH 8
           LKQ+ ANH
Sbjct: 413 LKQVHANH 420
>NP_058544
          Length = 594

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 242 KQIIANH 248
>NP_001030017
          Length = 601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L QIA NH+
Sbjct: 246 LNQIALNHK 254
>NP_001189788
          Length = 428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 94  KQIIANH 100
>NP_001123513
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 139 KQIIANH 145
>NP_003020
          Length = 474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 139 KQIIANH 145
>NP_001123512
          Length = 584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 249 KQIIANH 255
>NP_892113
          Length = 583

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 249 KQIIANH 255
>XP_005252109
          Length = 448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 96  KQIIANH 102
>XP_005245508
          Length = 488

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 139 KQIIANH 145
>XP_005245506
          Length = 598

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQI ANH
Sbjct: 249 KQIIANH 255
>NP_064695
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           +K+IAA H+
Sbjct: 234 IKEIAAKHK 242
>NP_056533
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KQIAANH 8
           KQIA NH
Sbjct: 519 KQIAYNH 525
>NP_001074007
          Length = 344

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           +K+IAA H+
Sbjct: 262 IKEIAAKHK 270
>XP_006726603
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQIAANHQ 9
           KQ+  NHQ
Sbjct: 268 KQLECNHQ 275
>XP_006725215
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQIAANHQ 9
           KQ+  NHQ
Sbjct: 268 KQLECNHQ 275
>XP_006725015
          Length = 361

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IAANHQ 9
           +AANHQ
Sbjct: 290 VAANHQ 295
>XP_006719237
          Length = 1263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQIAANHQ 9
           KQ+  NHQ
Sbjct: 268 KQLECNHQ 275
>XP_005250563
          Length = 172

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LKQIAANHQ 9
          +K+IAA H+
Sbjct: 90 IKEIAAKHK 98
>XP_005250422
          Length = 177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           +K+IAA H+
Sbjct: 95  IKEIAAKHK 103
>XP_005250421
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           +K+IAA H+
Sbjct: 234 IKEIAAKHK 242
>XP_005244875
          Length = 361

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IAANHQ 9
           +AANHQ
Sbjct: 290 VAANHQ 295
>NP_001255213
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+  NH+
Sbjct: 393 LKQLNLNHE 401
>NP_542166
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QIAANH 8
            Q+AANH
Sbjct: 1193 QLAANH 1198
>NP_056357
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QIAANH 8
            Q+AANH
Sbjct: 1193 QLAANH 1198
>NP_079337
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+  NH+
Sbjct: 393 LKQLNLNHE 401
>XP_005272554
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+  NH+
Sbjct: 393 LKQLNLNHE 401
>NP_001255214
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           LKQ+  NH+
Sbjct: 264 LKQLNLNHE 272
>NP_001120652
          Length = 2175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1780 LKQLTDNH 1787
>NP_000251
          Length = 2215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1818 LKQLTDNH 1825
>NP_001017423
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QIAA+ Q
Sbjct: 438 LRQIAASSQ 446
>NP_002851
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QIAA+ Q
Sbjct: 440 LRQIAASSQ 448
>NP_789792
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKQIAANH 8
           LKQ+  NH
Sbjct: 315 LKQLLKNH 322
>NP_694691
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1031 LRQIESGHQ 1039
>NP_694690
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1031 LRQIESGHQ 1039
>NP_066576
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1031 LRQIESGHQ 1039
>NP_940870
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKQIAANHQ 9
           LKQ+   HQ
Sbjct: 232 LKQVVYGHQ 240
>XP_003960381
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_005261866
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+QI + HQ
Sbjct: 893 LRQIESGHQ 901
>XP_005261865
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1044 LRQIESGHQ 1052
>XP_005261864
          Length = 1183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1044 LRQIESGHQ 1052
>XP_005261863
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1031 LRQIESGHQ 1039
>XP_005261862
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1044 LRQIESGHQ 1052
>XP_005261861
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1044 LRQIESGHQ 1052
>XP_005261860
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LKQIAANHQ 9
            L+QI + HQ
Sbjct: 1044 LRQIESGHQ 1052
>XP_006718624
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1780 LKQLTDNH 1787
>XP_005274069
          Length = 2176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1779 LKQLTDNH 1786
>XP_006718623
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1779 LKQLTDNH 1786
>XP_006718622
          Length = 2190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1780 LKQLTDNH 1787
>XP_006718621
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKQIAANH 8
            LKQ+  NH
Sbjct: 1815 LKQLTDNH 1822
>XP_006718281
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKQIAANH 8
           LKQ+  NH
Sbjct: 205 LKQLLKNH 212
>XP_006717996
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKQIAANHQ 9
           L+QIAA+ Q
Sbjct: 440 LRQIAASSQ 448
>XP_006715495
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKQIAANHQ 9
           LKQ+   HQ
Sbjct: 232 LKQVVYGHQ 240
>XP_006715494
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  LKQIAANHQ 9
          LKQ+   HQ
Sbjct: 6  LKQVVYGHQ 14
>XP_006715493
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKQIAANHQ 9
           LKQ+   HQ
Sbjct: 232 LKQVVYGHQ 240
>XP_006713898
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_003403469
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_006713897
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_006710216
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_003403820
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>XP_006710215
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKQIAANHQ 9
           L+Q+  NHQ
Sbjct: 325 LRQLWENHQ 333
>NP_115536
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQIAANHQ 9
           KQ+  NHQ
Sbjct: 228 KQLLHNHQ 235
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.120    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 402,859
Number of extensions: 621
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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