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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_038476                                                              18    1482
NP_872589                                                              18    1482
NP_776159                                                              17    2528
NP_001229342                                                           16    5631
NP_005575                                                              16    5631
NP_001160158                                                           16    5631
NP_006248                                                              16    5631
NP_001269574                                                           16    5631
NP_001269573                                                           16    5631
NP_997719                                                              16    5631
NP_079089                                                              16    5631
NP_000280                                                              16    5631
NP_001160160                                                           16    5631
XP_006719527                                                           16    5631
XP_006719526                                                           16    5631
XP_005269037                                                           16    5631
XP_005269036                                                           16    5631
XP_005269035                                                           16    5631
XP_005269034                                                           16    5631
XP_005269033                                                           16    5631
XP_005269032                                                           16    5631
XP_005269031                                                           16    5631
XP_005252554                                                           16    5631
XP_006717528                                                           16    5631
XP_005252553                                                           16    5631
XP_005271280                                                           16    5631
XP_006710968                                                           16    5631
NP_001160159                                                           16    5631
NP_065385                                                              16    7355
NP_001096045                                                           15    9605
NP_001273387                                                           15    9605
NP_071375                                                              15    9605
NP_003461                                                              15    9605
NP_001273386                                                           15    9605
XP_005255529                                                           15    9605
XP_005255527                                                           15    9605
XP_005255528                                                           15    9605

>NP_038476
          Length = 1556

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LKLRIRDFM 9
           L+LR+RDF+
Sbjct: 975 LELRLRDFL 983



>NP_872589
          Length = 1524

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LKLRIRDFM 9
           L+LR+RDF+
Sbjct: 943 LELRLRDFL 951



>NP_776159
          Length = 402

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LKLRIRDFM 9
           L+LR++DF+
Sbjct: 188 LRLRLKDFL 196



>NP_001229342
          Length = 643

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 373 IKLKIEDFI 381



>NP_005575
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKLRIRD 7
           +KLRIRD
Sbjct: 158 VKLRIRD 164



>NP_001160158
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 442 LKLRGRSFM 450



>NP_006248
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 373 IKLKIEDFI 381



>NP_001269574
          Length = 581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 248 IKLKIEDFI 256



>NP_001269573
          Length = 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 337 IKLKIEDFI 345



>NP_997719
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL++ DF+
Sbjct: 130 IKLKVEDFL 138



>NP_079089
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           L LRIR+F
Sbjct: 459 LNLRIREF 466



>NP_000280
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 371 LKLRGRSFM 379



>NP_001160160
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 371 LKLRGRSFM 379



>XP_006719527
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 371 LKLRGRSFM 379



>XP_006719526
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 371 LKLRGRSFM 379



>XP_005269037
          Length = 811

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 402 LKLRGRSFM 410



>XP_005269036
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 442 LKLRGRSFM 450



>XP_005269035
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 442 LKLRGRSFM 450



>XP_005269034
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 442 LKLRGRSFM 450



>XP_005269033
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 474 LKLRGRSFM 482



>XP_005269032
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 474 LKLRGRSFM 482



>XP_005269031
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 474 LKLRGRSFM 482



>XP_005252554
          Length = 697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 407 IKLKIEDFI 415



>XP_006717528
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 373 IKLKIEDFI 381



>XP_005252553
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKLRIRDFM 9
           +KL+I DF+
Sbjct: 407 IKLKIEDFI 415



>XP_005271280
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           L LRIR+F
Sbjct: 459 LNLRIREF 466



>XP_006710968
          Length = 579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           L LRIR+F
Sbjct: 459 LNLRIREF 466



>NP_001160159
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKLRIRDFM 9
           LKLR R FM
Sbjct: 371 LKLRGRSFM 379



>NP_065385
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLRIRDFM 9
           +LR RDF+
Sbjct: 653 RLRFRDFV 660



>NP_001096045
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KLRIRDF 8
           ++R+RDF
Sbjct: 586 QIRVRDF 592



>NP_001273387
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           LK++I DF
Sbjct: 782 LKMKITDF 789



>NP_071375
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKLRIRD 7
           L+LR+RD
Sbjct: 657 LRLRLRD 663



>NP_003461
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           LK++I DF
Sbjct: 881 LKMKITDF 888



>NP_001273386
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKLRIRDF 8
           LK++I DF
Sbjct: 865 LKMKITDF 872



>XP_005255529
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKLRIRD 7
           L+LR+RD
Sbjct: 239 LRLRLRD 245



>XP_005255527
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKLRIRD 7
           L+LR+RD
Sbjct: 541 LRLRLRD 547



>XP_005255528
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKLRIRD 7
           L+LR+RD
Sbjct: 685 LRLRLRD 691



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.354    0.165    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 486,374
Number of extensions: 807
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)