Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_112477                                                              16    7355
NP_001243298                                                           16    7355
NP_006632                                                              16    7355
NP_001036216                                                           15    9605
NP_001036214                                                           15    9605
NP_006594                                                              15    9605
NP_001036215                                                           15    9605
NP_001269347                                                           15    9605
XP_006724791                                                           15    9605
XP_005262418                                                           15    9605
XP_005262417                                                           15    9605
XP_005262416                                                           15    9605
XP_005262415                                                           15    9605
XP_006724790                                                           15    9605
XP_005262414                                                           15    9605

>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1418 LKLMSKILQ 1426



>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1439 LKLMSKILQ 1447



>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1449 LKLMSKILQ 1457



>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1449 LKLMSKILQ 1457



>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1449 LKLMSKILQ 1457



>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1418 LKLMSKILQ 1426



>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1428 LKLMSKILQ 1436



>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1449 LKLMSKILQ 1457



>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1436 LKLMSKILQ 1444



>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1439 LKLMSKILQ 1447



>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LKLMSMILQ 9
            LKLMS ILQ
Sbjct: 1449 LKLMSKILQ 1457



>NP_112477
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKLMSMILQ 9
           LKL SM+L+
Sbjct: 353 LKLSSMLLE 361



>NP_001243298
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKLMSMILQ 9
           LKL SM+L+
Sbjct: 341 LKLSSMLLE 349



>NP_006632
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKLMSMILQ 9
           LKL SM+L+
Sbjct: 341 LKLSSMLLE 349



>NP_001036216
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>NP_001036214
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>NP_006594
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>NP_001036215
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>NP_001269347
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_006724791
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 322 IKLLTLVLQ 330



>XP_005262418
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_005262417
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_005262416
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_005262415
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_006724790
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



>XP_005262414
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LKLMSMILQ 9
           +KL++++LQ
Sbjct: 391 IKLLTLVLQ 399



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.144    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 222,583
Number of extensions: 233
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)