Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              19     869
NP_001035820                                                           17    3301
NP_001035822                                                           17    3301
NP_001035816                                                           17    3301
NP_001035823                                                           17    3301
NP_001035818                                                           17    3301
NP_056420                                                              17    3301
NP_001035817                                                           17    3301
NP_001258579                                                           17    3301
NP_071906                                                              17    3301
NP_001127905                                                           17    3301
NP_001127904                                                           17    3301
XP_006726580                                                           17    3301
XP_006726579                                                           17    3301
XP_005270372                                                           17    3301
XP_006717817                                                           17    3301
XP_005277709                                                           17    3301
XP_005265449                                                           17    3301
NP_001036064                                                           16    5631
NP_005226                                                              16    5631
NP_075601                                                              16    5631
XP_006725234                                                           16    5631
XP_005268112                                                           16    5631
XP_005246434                                                           16    5631
XP_005246433                                                           16    5631
XP_005246432                                                           16    5631
XP_006712427                                                           16    5631
NP_987102                                                              16    7355
NP_002077                                                              16    7355
NP_001008723                                                           16    7355
NP_001128128                                                           16    7355
NP_997287                                                              16    7355
NP_001128668                                                           15    9605
NP_001017975                                                           15    9605
NP_001278017                                                           15    9605
NP_114157                                                              15    9605
NP_055592                                                              15    9605
XP_006723602                                                           15    9605
XP_005260717                                                           15    9605
XP_006723474                                                           15    9605
XP_005259362                                                           15    9605
XP_006717666                                                           15    9605
XP_005269535                                                           15    9605
XP_006717665                                                           15    9605
XP_005269533                                                           15    9605
XP_005269534                                                           15    9605
XP_005273417                                                           15    9605
NP_542789                                                              15    9605
>NP_002430
          Length = 1137

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKILNEQ A
Sbjct: 686 LKILNEQAA 694
>NP_001035820
          Length = 217

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 138 LKILEEKTA 146
>NP_001035822
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>NP_001035816
          Length = 420

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 147 LKILEEKTA 155
>NP_001035823
          Length = 145

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>NP_001035818
          Length = 269

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 138 LKILEEKTA 146
>NP_056420
          Length = 226

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 147 LKILEEKTA 155
>NP_001035817
          Length = 411

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 138 LKILEEKTA 146
>NP_001258579
          Length = 280

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LKILNEQ 7
          LK+LNEQ
Sbjct: 9  LKVLNEQ 15
>NP_071906
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKILNEQ 7
           LK+LNEQ
Sbjct: 121 LKVLNEQ 127
>NP_001127905
          Length = 232

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKILNEQ 7
           LK+LNEQ
Sbjct: 121 LKVLNEQ 127
>NP_001127904
          Length = 243

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKILNEQ 7
           LK+LNEQ
Sbjct: 121 LKVLNEQ 127
>XP_006726580
          Length = 116

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>XP_006726579
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>XP_005270372
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>XP_006717817
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LKIL E+TA
Sbjct: 147 LKILEEKTA 155
>XP_005277709
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKILNEQTA 9
          LKIL E+TA
Sbjct: 66 LKILEEKTA 74
>XP_005265449
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKILNEQ 7
           LK+LNEQ
Sbjct: 121 LKVLNEQ 127
>NP_001036064
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 750 IKILNETT 757
>NP_005226
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 750 IKILNETT 757
>NP_075601
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LK+ N+Q+A
Sbjct: 119 LKVFNDQSA 127
>XP_006725234
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LK+ N+Q+A
Sbjct: 120 LKVFNDQSA 128
>XP_005268112
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           LK+ N+Q+A
Sbjct: 120 LKVFNDQSA 128
>XP_005246434
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 740 IKILNETT 747
>XP_005246433
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 740 IKILNETT 747
>XP_005246432
          Length = 1307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 765 IKILNETT 772
>XP_006712427
          Length = 1323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           +KILNE T
Sbjct: 765 IKILNETT 772
>NP_987102
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKILNEQ 7
          LK+LNE+
Sbjct: 25 LKVLNEE 31
>NP_002077
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LKILNEQ 7
          LK+LNE+
Sbjct: 25 LKVLNEE 31
>NP_001008723
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KILNEQTA 9
           KILNE+ A
Sbjct: 264 KILNERAA 271
>NP_001128128
          Length = 452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KILNEQ 7
           KILNEQ
Sbjct: 210 KILNEQ 215
>NP_997287
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KILNEQ 7
           KILNEQ
Sbjct: 184 KILNEQ 189
>NP_001128668
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 520 LKVLDEKT 527
>NP_001017975
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LKILNEQT 8
          LKI NE T
Sbjct: 74 LKITNEDT 81
>NP_001278017
          Length = 2912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KILNEQT 8
            K++NE+T
Sbjct: 1239 KVINEET 1245
>NP_114157
          Length = 2873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KILNEQT 8
            K++NE+T
Sbjct: 1200 KVINEET 1206
>NP_055592
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           +KI+NE+ A
Sbjct: 100 VKIINERVA 108
>XP_006723602
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           LK+ NE+T
Sbjct: 556 LKLANEET 563
>XP_005260717
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           LK+ NE+T
Sbjct: 555 LKLANEET 562
>XP_006723474
          Length = 2737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KILNEQT 8
            K++NE+T
Sbjct: 1064 KVINEET 1070
>XP_005259362
          Length = 2855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KILNEQT 8
            K++NE+T
Sbjct: 1182 KVINEET 1188
>XP_006717666
          Length = 1289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 374 LKVLDEKT 381
>XP_005269535
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 520 LKVLDEKT 527
>XP_006717665
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 520 LKVLDEKT 527
>XP_005269533
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 520 LKVLDEKT 527
>XP_005269534
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKILNEQT 8
           LK+L+E+T
Sbjct: 520 LKVLDEKT 527
>XP_005273417
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LKILNEQTA 9
           +KI+NE+ A
Sbjct: 100 VKIINERVA 108
>NP_542789
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKILNEQT 8
           LK+ NE+T
Sbjct: 530 LKLANEET 537
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.125    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,399
Number of extensions: 911
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package