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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001171559                                                           17    4312
NP_982271                                                              17    4312
NP_001153774                                                           17    4312
NP_003886                                                              17    4312
NP_003889                                                              17    4312
NP_001153778                                                           17    4312
XP_005261137                                                           17    4312
XP_006724126                                                           17    4312
XP_006724125                                                           17    4312
XP_006724124                                                           17    4312
XP_005261133                                                           17    4312
XP_006724123                                                           17    4312
XP_006724122                                                           17    4312
XP_006724121                                                           17    4312
XP_005267256                                                           17    4312
XP_005267255                                                           17    4312
XP_006715655                                                           17    4312
XP_005267254                                                           17    4312
XP_006715654                                                           17    4312
NP_001271230                                                           16    5631
NP_001271231                                                           16    5631
NP_061155                                                              16    5631
XP_006715810                                                           16    5631
XP_006715809                                                           16    5631
NP_001001670                                                           16    7355
NP_997299                                                              16    7355
NP_001138669                                                           16    7355
XP_005276416                                                           16    7355
NP_060209                                                              15    9605
NP_001277059                                                           15    9605
NP_001277058                                                           15    9605
NP_001230695                                                           15    9605
XP_005258481                                                           15    9605
XP_006710819                                                           15    9605
XP_006710818                                                           15    9605
XP_005271067                                                           15    9605

>NP_001171559
          Length = 1259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 220 LKDGARSMS 228



>NP_982271
          Length = 1350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 491 LKDGARSVT 499



>NP_001153774
          Length = 1295

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 452 LKDGARSVT 460



>NP_003886
          Length = 1612

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 491 LKDGARSVT 499



>NP_003889
          Length = 1496

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 457 LKDGARSMS 465



>NP_001153778
          Length = 1526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_005261137
          Length = 1264

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_006724126
          Length = 1313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_006724125
          Length = 1313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_006724124
          Length = 1534

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_005261133
          Length = 1557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 452 LKDGARSVT 460



>XP_006724123
          Length = 1560

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_006724122
          Length = 1568

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_006724121
          Length = 1576

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARSV+
Sbjct: 455 LKDGARSVT 463



>XP_005267256
          Length = 1113

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDTARSVS 9
          LKD ARS+S
Sbjct: 74 LKDGARSMS 82



>XP_005267255
          Length = 1165

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 126 LKDGARSMS 134



>XP_006715655
          Length = 1288

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 457 LKDGARSMS 465



>XP_005267254
          Length = 1443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 404 LKDGARSMS 412



>XP_006715654
          Length = 1495

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKDTARSVS 9
           LKD ARS+S
Sbjct: 456 LKDGARSMS 464



>NP_001271230
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKDTARS 7
           LKDT+RS
Sbjct: 596 LKDTSRS 602



>NP_001271231
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKDTARS 7
           LKDT+RS
Sbjct: 595 LKDTSRS 601



>NP_061155
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKDTARS 7
           LKDT+RS
Sbjct: 633 LKDTSRS 639



>XP_006715810
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKDTARS 7
           LKDT+RS
Sbjct: 596 LKDTSRS 602



>XP_006715809
          Length = 1142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKDTARS 7
           LKDT+RS
Sbjct: 633 LKDTSRS 639



>NP_001001670
          Length = 1576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKDTARSVS 9
           LKD A SVS
Sbjct: 149 LKDAAPSVS 157



>NP_997299
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKDTARSVS 9
           LKD A SVS
Sbjct: 146 LKDAAPSVS 154



>NP_001138669
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKDTARSVS 9
           LKD A SVS
Sbjct: 146 LKDAAPSVS 154



>XP_005276416
          Length = 1583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LKDTARSVS 9
           LKD A SVS
Sbjct: 122 LKDAAPSVS 130



>NP_060209
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 185 LKDTAKAL 192



>NP_001277059
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LKDTARSV 8
          LKDTA+++
Sbjct: 42 LKDTAKAL 49



>NP_001277058
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 163 LKDTAKAL 170



>NP_001230695
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 185 LKDTAKAL 192



>XP_005258481
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LKDTARSV 8
          LK+T RS+
Sbjct: 48 LKETGRSI 55



>XP_006710819
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 185 LKDTAKAL 192



>XP_006710818
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 185 LKDTAKAL 192



>XP_005271067
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKDTARSV 8
           LKDTA+++
Sbjct: 185 LKDTAKAL 192



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.113    0.262 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,843
Number of extensions: 359
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)