Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           18    1135
NP_001277143                                                           18    1135
NP_001077383                                                           18    1135
NP_001320                                                              18    1135
NP_073713                                                              18    1135
XP_005269629                                                           18    1135
XP_005269628                                                           18    1135
XP_005269627                                                           18    1135
XP_005269626                                                           18    1135
XP_006717706                                                           18    1135
XP_005269625                                                           18    1135
XP_005269624                                                           18    1135
XP_006717705                                                           18    1135
XP_005269622                                                           18    1135
XP_005269621                                                           18    1135
XP_006717704                                                           18    1135
XP_005269619                                                           18    1135
XP_005269618                                                           18    1135
NP_001319                                                              17    2528
NP_001012632                                                           17    2528
XP_005272320                                                           17    2528
XP_005272319                                                           17    2528
XP_005272318                                                           17    2528
>NP_001277144
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>NP_001277143
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>NP_001077383
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>NP_001320
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>NP_073713
          Length = 985

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKDLAIVAF 9
           LKDLA VAF
Sbjct: 591 LKDLATVAF 599
>XP_005269629
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269628
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269627
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269626
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_006717706
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269625
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269624
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_006717705
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269622
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269621
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_006717704
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269619
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>XP_005269618
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKDLA VAF
Sbjct: 51 LKDLATVAF 59
>NP_001319
          Length = 440

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKD+A VAF
Sbjct: 45 LKDVATVAF 53
>NP_001012632
          Length = 429

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKD+A VAF
Sbjct: 34 LKDVATVAF 42
>XP_005272320
          Length = 430

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKD+A VAF
Sbjct: 34 LKDVATVAF 42
>XP_005272319
          Length = 430

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKD+A VAF
Sbjct: 34 LKDVATVAF 42
>XP_005272318
          Length = 441

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LKDLAIVAF 9
          LKD+A VAF
Sbjct: 45 LKDVATVAF 53
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.153    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 416,540
Number of extensions: 587
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package