Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1482
NP_001138386                                                           18    1482
NP_000132                                                              18    1482
NP_075259                                                              18    1482
NP_001138385                                                           18    1482
XP_006717776                                                           18    1482
XP_006717773                                                           18    1482
XP_006717772                                                           18    1482
XP_006717771                                                           18    1482
NP_001191243                                                           17    4312
NP_000940                                                              17    4312
NP_001191245                                                           17    4312
NP_001191244                                                           17    4312
XP_006714547                                                           17    4312
NP_001070                                                              16    5631
NP_055426                                                              16    5631
XP_005248757                                                           16    5631
XP_006715468                                                           16    5631
XP_005248756                                                           16    5631
XP_006715467                                                           16    5631
XP_006712791                                                           16    5631
XP_005264072                                                           16    5631
NP_062618                                                              16    5631
NP_001273596                                                           16    7355
NP_001273595                                                           16    7355
NP_001273594                                                           16    7355
NP_001129406                                                           16    7355
NP_001129407                                                           16    7355
NP_006466                                                              16    7355
NP_001129408                                                           16    7355
NP_001273004                                                           16    7355
NP_004311                                                              16    7355
NP_775293                                                              16    7355
NP_001139746                                                           16    7355
NP_001185460                                                           16    7355
NP_076996                                                              16    7355
NP_444504                                                              16    7355
XP_005266289                                                           16    7355
XP_005266288                                                           16    7355
XP_005270159                                                           16    7355
XP_005270157                                                           16    7355
XP_005270153                                                           16    7355
XP_005270152                                                           16    7355
XP_005270151                                                           16    7355
XP_005270150                                                           16    7355
XP_005270149                                                           16    7355
XP_005270148                                                           16    7355
XP_005270142                                                           16    7355
XP_005270141                                                           16    7355
XP_005270140                                                           16    7355
XP_005270139                                                           16    7355
XP_005270136                                                           16    7355
XP_005270135                                                           16    7355
XP_005270134                                                           16    7355
XP_005270133                                                           16    7355
XP_005270132                                                           16    7355
XP_005270131                                                           16    7355
XP_005270130                                                           16    7355
XP_005270128                                                           16    7355
XP_006714561                                                           16    7355
XP_006710372                                                           16    7355
XP_005270458                                                           16    7355
XP_005270457                                                           16    7355
NP_612417                                                              16    7355
NP_116242                                                              15    9605
>NP_001138389
          Length = 705

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LIVEYLQIK 9
          LI EYLQIK
Sbjct: 87 LIGEYLQIK 95
>NP_001138386
          Length = 709

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LIVEYLQIK 9
          LI EYLQIK
Sbjct: 87 LIGEYLQIK 95
>NP_000132
          Length = 821

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LIVEYLQIK 9
          LI EYLQIK
Sbjct: 87 LIGEYLQIK 95
>NP_075259
          Length = 822

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LIVEYLQIK 9
          LI EYLQIK
Sbjct: 87 LIGEYLQIK 95
>NP_001138385
          Length = 769

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LIVEYLQIK 9
          LI EYLQIK
Sbjct: 87 LIGEYLQIK 95
>XP_006717776
          Length = 806

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           LI EYLQIK
Sbjct: 106 LIGEYLQIK 114
>XP_006717773
          Length = 807

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           LI EYLQIK
Sbjct: 106 LIGEYLQIK 114
>XP_006717772
          Length = 838

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           LI EYLQIK
Sbjct: 106 LIGEYLQIK 114
>XP_006717771
          Length = 839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           LI EYLQIK
Sbjct: 106 LIGEYLQIK 114
>NP_001191243
          Length = 521

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LIVEYLQI 8
           L+VEYL++
Sbjct: 209 LLVEYLEV 216
>NP_000940
          Length = 622

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LIVEYLQI 8
           L+VEYL++
Sbjct: 310 LLVEYLEV 317
>NP_001191245
          Length = 376

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LIVEYLQI 8
           L+VEYL++
Sbjct: 310 LLVEYLEV 317
>NP_001191244
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LIVEYLQI 8
           L+VEYL++
Sbjct: 310 LLVEYLEV 317
>XP_006714547
          Length = 622

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LIVEYLQI 8
           L+VEYL++
Sbjct: 310 LLVEYLEV 317
>NP_001070
          Length = 619

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +VEYL++K
Sbjct: 235 LVEYLKLK 242
>NP_055426
          Length = 5596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LIVEYLQ 7
            LIV+YLQ
Sbjct: 2372 LIVQYLQ 2378
>XP_005248757
          Length = 3591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIVEYLQ 7
           LIV+YLQ
Sbjct: 367 LIVQYLQ 373
>XP_006715468
          Length = 3744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIVEYLQ 7
           LIV+YLQ
Sbjct: 520 LIVQYLQ 526
>XP_005248756
          Length = 3905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIVEYLQ 7
           LIV+YLQ
Sbjct: 681 LIVQYLQ 687
>XP_006715467
          Length = 5550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LIVEYLQ 7
            LIV+YLQ
Sbjct: 2372 LIVQYLQ 2378
>XP_006712791
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +VEYL++K
Sbjct: 235 LVEYLKLK 242
>XP_005264072
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +VEYL++K
Sbjct: 235 LVEYLKLK 242
>NP_062618
          Length = 254

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  EYLQIK 9
          EYLQIK
Sbjct: 43 EYLQIK 48
>NP_001273596
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001273595
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001273594
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001129406
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001129407
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_006466
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001129408
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>NP_001273004
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   IVEYLQ 7
           IVEYLQ
Sbjct: 562 IVEYLQ 567
>NP_004311
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   IVEYLQ 7
           IVEYLQ
Sbjct: 687 IVEYLQ 692
>NP_775293
          Length = 1001

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   IVEYLQ 7
           IVEYLQ
Sbjct: 687 IVEYLQ 692
>NP_001139746
          Length = 602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>NP_001185460
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>NP_076996
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVEYLQIK 9
           +VEYLQ K
Sbjct: 643 LVEYLQRK 650
>NP_444504
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           L+ +YL+IK
Sbjct: 351 LLYQYLEIK 359
>XP_005266289
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>XP_005266288
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IVEYLQIK 9
           +++Y+QIK
Sbjct: 647 LIKYIQIK 654
>XP_005270159
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270157
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270153
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270152
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270151
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270150
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270149
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270148
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270142
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270141
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270140
          Length = 620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270139
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270136
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270135
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270134
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270133
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270132
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270131
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270130
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_005270128
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           + V+YLQ+K
Sbjct: 147 IAVQYLQMK 155
>XP_006714561
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVEYLQIK 9
           +VEYLQ K
Sbjct: 643 LVEYLQRK 650
>XP_006710372
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           L+ +YL+IK
Sbjct: 184 LLYQYLEIK 192
>XP_005270458
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           L+ +YL+IK
Sbjct: 309 LLYQYLEIK 317
>XP_005270457
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIVEYLQIK 9
           L+ +YL+IK
Sbjct: 351 LLYQYLEIK 359
>NP_612417
          Length = 213

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VEYLQIK 9
           VE+LQIK
Sbjct: 123 VEWLQIK 129
>NP_116242
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LIVEYLQ 7
           L+V+YLQ
Sbjct: 628 LVVKYLQ 634
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.154    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,305
Number of extensions: 724
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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