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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005179                                                              18    1135
NP_733762                                                              18    1135
XP_006713860                                                           18    1135
XP_006713859                                                           18    1135
XP_005247910                                                           18    1135
XP_005247909                                                           18    1135
NP_001275964                                                           17    3301
NP_001275963                                                           17    3301
NP_612352                                                              17    3301
NP_958930                                                              17    3301
NP_958929                                                              17    3301
NP_958931                                                              17    3301
NP_667338                                                              16    5631
NP_001159608                                                           16    5631
NP_003276                                                              16    5631
XP_006713923                                                           16    5631
XP_006713922                                                           16    5631
XP_006717881                                                           15    9605

>NP_005179
          Length = 906

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 215 ISSGLEAM 222



>NP_733762
          Length = 982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 207 ISSGLEAM 214



>XP_006713860
          Length = 914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 235 ISSGLEAM 242



>XP_006713859
          Length = 966

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 235 ISSGLEAM 242



>XP_005247910
          Length = 982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 207 ISSGLEAM 214



>XP_005247909
          Length = 1010

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ISSGLEAM 9
           ISSGLEAM
Sbjct: 235 ISSGLEAM 242



>NP_001275964
          Length = 542

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 28 LVSQGLEAL 36



>NP_001275963
          Length = 619

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 28 LVSQGLEAL 36



>NP_612352
          Length = 315

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 28 LVSQGLEAL 36



>NP_958930
          Length = 619

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 28 LVSQGLEAL 36



>NP_958929
          Length = 619

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 28 LVSQGLEAL 36



>NP_958931
          Length = 637

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LISSGLEAM 9
          L+S GLEA+
Sbjct: 46 LVSQGLEAL 54



>NP_667338
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LISSGLEAM 9
            LIS GLE M
Sbjct: 1203 LISRGLEKM 1211



>NP_001159608
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LISSGLEAM 9
            LIS GLE M
Sbjct: 1123 LISRGLEKM 1131



>NP_003276
          Length = 1358

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LISSGLEA 8
          L SSGLEA
Sbjct: 78 LCSSGLEA 85



>XP_006713923
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LISSGLEAM 9
            LIS GLE M
Sbjct: 1123 LISRGLEKM 1131



>XP_006713922
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LISSGLEAM 9
            LIS GLE M
Sbjct: 1203 LISRGLEKM 1211



>XP_006717881
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSGLEAM 9
           SSGLEA+
Sbjct: 129 SSGLEAV 135



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,289
Number of extensions: 566
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)