Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     869
NP_004561                                                              19     869
NP_001275703                                                           19     869
XP_005253450                                                           19     869
XP_006719151                                                           19     869
NP_775945                                                              17    3301
XP_006715526                                                           17    3301
XP_005266998                                                           17    3301
NP_000042                                                              16    5631
NP_115495                                                              16    5631
XP_006718908                                                           16    5631
XP_005271621                                                           16    5631
XP_006718907                                                           16    5631
XP_006718906                                                           16    5631
XP_005271619                                                           16    5631
XP_005271618                                                           16    5631
NP_001127854                                                           16    7355
NP_055684                                                              16    7355
NP_001364                                                              16    7355
NP_001164209                                                           16    7355
XP_006711798                                                           16    7355
NP_056047                                                              16    7355
NP_003733                                                              15    9605
NP_001265121                                                           15    9605
NP_938149                                                              15    9605
NP_001265122                                                           15    9605
NP_001265123                                                           15    9605
NP_938148                                                              15    9605
NP_000353                                                              15    9605
NP_620686                                                              15    9605
NP_002363                                                              15    9605
NP_653200                                                              15    9605
NP_001128181                                                           15    9605
NP_055520                                                              15    9605
NP_001036199                                                           15    9605
NP_110445                                                              15    9605
NP_003463                                                              15    9605
NP_001104595                                                           15    9605
NP_036533                                                              15    9605
NP_116098                                                              15    9605
XP_005276778                                                           15    9605
XP_005276777                                                           15    9605
XP_005274830                                                           15    9605
XP_005262408                                                           15    9605
XP_006724647                                                           15    9605
XP_006724646                                                           15    9605
XP_006724645                                                           15    9605
XP_006724644                                                           15    9605
XP_006724643                                                           15    9605
XP_006724642                                                           15    9605
XP_005261968                                                           15    9605
XP_005261966                                                           15    9605
XP_005261967                                                           15    9605
XP_006724476                                                           15    9605
XP_005261965                                                           15    9605
XP_006722977                                                           15    9605
XP_005260143                                                           15    9605
XP_005260145                                                           15    9605
XP_005260142                                                           15    9605
XP_005260144                                                           15    9605
XP_005254968                                                           15    9605
XP_005254967                                                           15    9605
XP_006720570                                                           15    9605
XP_006718108                                                           15    9605
XP_006716252                                                           15    9605
XP_006716251                                                           15    9605
XP_005249448                                                           15    9605
XP_005262748                                                           15    9605
XP_006712881                                                           15    9605
XP_006712880                                                           15    9605
XP_005276172                                                           15    9605
NP_055890                                                              15    9605
NP_006113                                                              15    9605
>NP_001275701
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           LILQRKG N
Sbjct: 458 LILQRKGEN 466
>NP_004561
          Length = 1445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           LILQRKG N
Sbjct: 458 LILQRKGEN 466
>NP_001275703
          Length = 1264

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           LILQRKG N
Sbjct: 236 LILQRKGEN 244
>XP_005253450
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           LILQRKG N
Sbjct: 458 LILQRKGEN 466
>XP_006719151
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           LILQRKG N
Sbjct: 458 LILQRKGEN 466
>NP_775945
          Length = 539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 219 VLQRKGIS 226
>XP_006715526
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 266 VLQRKGIS 273
>XP_005266998
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 266 VLQRKGIS 273
>NP_000042
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>NP_115495
          Length = 6306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LILQRKGVN 9
            ++LQ+ GVN
Sbjct: 5417 VVLQKDGVN 5425
>XP_006718908
          Length = 1708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 1293 QRKGIN 1298
>XP_005271621
          Length = 2708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2293 QRKGIN 2298
>XP_006718907
          Length = 3050

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2635 QRKGIN 2640
>XP_006718906
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>XP_005271619
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>XP_005271618
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRKGVN 9
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>NP_001127854
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 549 LLQRKGLS 556
>NP_055684
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 563 LLQRKGLS 570
>NP_001364
          Length = 4515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LQRKGVN 9
            LQR GVN
Sbjct: 3806 LQRTGVN 3812
>NP_001164209
          Length = 1182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 690 LLQRKGLS 697
>XP_006711798
          Length = 4586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LQRKGVN 9
            LQR GVN
Sbjct: 3868 LQRTGVN 3874
>NP_056047
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQRKG++
Sbjct: 387 LLQRKGLS 394
>NP_003733
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILQRKGV 8
           +L+RKGV
Sbjct: 643 LLERKGV 649
>NP_001265121
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           L+L++ G+N
Sbjct: 834 LVLRKPGIN 842
>NP_938149
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           L+L++ G+N
Sbjct: 948 LVLRKPGIN 956
>NP_001265122
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           L+L++ G+N
Sbjct: 812 LVLRKPGIN 820
>NP_001265123
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           L+L++ G+N
Sbjct: 829 LVLRKPGIN 837
>NP_938148
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LILQRKGVN 9
           L+L++ G+N
Sbjct: 926 LVLRKPGIN 934
>NP_000353
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRKGVN 9
           QRKG+N
Sbjct: 131 QRKGLN 136
>NP_620686
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILQRKGV 8
           +LQR+GV
Sbjct: 156 LLQRRGV 162
>NP_002363
          Length = 1144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    LILQRKG 7
            LIL RKG
Sbjct: 1068 LILHRKG 1074
>NP_653200
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  ILQRKGV 8
          +LQ+KG+
Sbjct: 47 VLQKKGI 53
>NP_001128181
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LILQRKGVN 9
           L L+R GVN
Sbjct: 130 LDLERSGVN 138
>NP_055520
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILQRKGV 8
            +LQR+GV
Sbjct: 1394 VLQREGV 1400
>NP_001036199
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQ+KGV+
Sbjct: 349 LLQQKGVD 356
>NP_110445
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>NP_003463
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LILQRKGVN 9
           L L+R GVN
Sbjct: 164 LDLERSGVN 172
>NP_001104595
          Length = 1488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 792 ILERKGLS 799
>NP_036533
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>NP_116098
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LQRKGVN 9
          LQR GVN
Sbjct: 53 LQRLGVN 59
>XP_005276778
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILQRKG 7
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005276777
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILQRKG 7
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005274830
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILQRKG 7
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005262408
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILQRKG 7
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_006724647
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724646
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724645
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724644
          Length = 1244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724643
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 587 ILERKGLS 594
>XP_006724642
          Length = 1520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_005261968
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261966
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261967
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_006724476
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261965
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILQRKGVN 9
           +LQR G+N
Sbjct: 466 VLQRGGLN 473
>XP_006722977
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260143
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260145
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260142
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260144
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 QRKGVN 9
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005254968
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    LILQRKG 7
            LIL RKG
Sbjct: 1080 LILHRKG 1086
>XP_005254967
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    LILQRKG 7
            LIL RKG
Sbjct: 1099 LILHRKG 1105
>XP_006720570
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    LILQRKG 7
            LIL RKG
Sbjct: 1105 LILHRKG 1111
>XP_006718108
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LQRKGVN 9
          LQR GVN
Sbjct: 53 LQRLGVN 59
>XP_006716252
          Length = 1937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILQRKGV 8
            +LQR+GV
Sbjct: 1403 VLQREGV 1409
>XP_006716251
          Length = 1975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILQRKGV 8
            +LQR+GV
Sbjct: 1403 VLQREGV 1409
>XP_005249448
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LILQRKGVN 9
           L L+R GVN
Sbjct: 164 LDLERSGVN 172
>XP_005262748
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           +LQ+KGV+
Sbjct: 380 LLQQKGVD 387
>XP_006712881
          Length = 1335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILQRKGV 8
           +L+RKGV
Sbjct: 657 LLERKGV 663
>XP_006712880
          Length = 1335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILQRKGV 8
           +L+RKGV
Sbjct: 657 LLERKGV 663
>XP_005276172
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILQRKG 7
           +LQRKG
Sbjct: 119 VLQRKG 124
>NP_055890
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILQRKGVN 9
           IL+RKG++
Sbjct: 587 ILERKGLS 594
>NP_006113
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    LILQRKG 7
            LIL RKG
Sbjct: 1074 LILHRKG 1080
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.149    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,374
Number of extensions: 811
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package