Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_055160                                                              16    5631
NP_065986                                                              15    9605
NP_058626                                                              15    9605
XP_005248029                                                           15    9605
XP_005246781                                                           15    9605
XP_005246779                                                           15    9605
XP_005246778                                                           15    9605
XP_005246777                                                           15    9605
XP_005270863                                                           15    9605
XP_005270862                                                           15    9605
XP_006710667                                                           15    9605
XP_006710666                                                           15    9605
NP_001139108                                                           15    9605

>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           LILEISKL+
Sbjct: 695 LILEISKLK 703



>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           LILEISKL+
Sbjct: 695 LILEISKLK 703



>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           LILEISKL+
Sbjct: 695 LILEISKLK 703



>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           LILEISKL+
Sbjct: 695 LILEISKLK 703



>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           LILEISKL+
Sbjct: 695 LILEISKLK 703



>NP_055160
          Length = 2279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LILEISKLQ 9
           L++E+S+LQ
Sbjct: 941 LLVEVSRLQ 949



>NP_065986
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LEISKLQ 9
           LE+SK+Q
Sbjct: 925 LEVSKIQ 931



>NP_058626
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILEISKLQ 9
           ++EIS+LQ
Sbjct: 260 VVEISRLQ 267



>XP_005248029
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILEISKLQ 9
           ++EIS+LQ
Sbjct: 179 VVEISRLQ 186



>XP_005246781
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LEISKLQ 9
           LE+SK+Q
Sbjct: 903 LEVSKIQ 909



>XP_005246779
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LEISKLQ 9
           LE+SK+Q
Sbjct: 925 LEVSKIQ 931



>XP_005246778
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LEISKLQ 9
           LE+SK+Q
Sbjct: 925 LEVSKIQ 931



>XP_005246777
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LEISKLQ 9
           LE+SK+Q
Sbjct: 925 LEVSKIQ 931



>XP_005270863
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILEISKLQ 9
           + EISKLQ
Sbjct: 270 VKEISKLQ 277



>XP_005270862
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILEISKLQ 9
           + EISKLQ
Sbjct: 270 VKEISKLQ 277



>XP_006710667
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILEISKLQ 9
           + EISKLQ
Sbjct: 270 VKEISKLQ 277



>XP_006710666
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILEISKLQ 9
           + EISKLQ
Sbjct: 270 VKEISKLQ 277



>NP_001139108
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILEISKLQ 9
           + EISKLQ
Sbjct: 270 VKEISKLQ 277



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.146    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 376,036
Number of extensions: 628
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)