Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689772                                                              19     869
NP_542158                                                              18    1482
NP_001258297                                                           18    1482
NP_000953                                                              18    1482
NP_001258094                                                           18    1482
NP_001258296                                                           18    1482
NP_001258093                                                           18    1482
NP_001258095                                                           18    1482
XP_006717255                                                           18    1482
XP_005252162                                                           18    1482
NP_054831                                                              18    1935
NP_056137                                                              18    1935
NP_001269832                                                           18    1935
NP_001269831                                                           18    1935
XP_005251106                                                           18    1935
XP_006716688                                                           18    1935
XP_006716687                                                           18    1935
NP_005535                                                              17    4312
XP_006712575                                                           17    4312
XP_005246591                                                           17    4312
NP_001275722                                                           16    5631
XP_006720433                                                           16    5631
NP_997204                                                              16    5631
NP_000780                                                              16    7355
NP_076435                                                              16    7355
NP_001245200                                                           15    9605
NP_000240                                                              15    9605
NP_001161089                                                           15    9605
NP_938205                                                              15    9605
NP_001171988                                                           15    9605
NP_078893                                                              15    9605
NP_001127860                                                           15    9605
NP_001127859                                                           15    9605
NP_060576                                                              15    9605
NP_001127861                                                           15    9605
NP_859064                                                              15    9605
NP_803430                                                              15    9605
NP_803429                                                              15    9605
NP_803252                                                              15    9605
NP_783863                                                              15    9605
NP_944489                                                              15    9605
NP_037413                                                              15    9605
XP_005260739                                                           15    9605
XP_005269276                                                           15    9605
XP_006719749                                                           15    9605
XP_005269275                                                           15    9605
XP_006717349                                                           15    9605
XP_005252266                                                           15    9605
XP_005252265                                                           15    9605
XP_005252264                                                           15    9605
XP_006717348                                                           15    9605
XP_006717347                                                           15    9605
XP_006717346                                                           15    9605
XP_005249851                                                           15    9605
XP_005249852                                                           15    9605
XP_005249853                                                           15    9605
XP_006715813                                                           15    9605
XP_005249850                                                           15    9605
XP_005265218                                                           15    9605
XP_005264228                                                           15    9605
XP_005264226                                                           15    9605
XP_006712018                                                           15    9605
XP_005264225                                                           15    9605
XP_005264224                                                           15    9605
XP_005264223                                                           15    9605
NP_001035194                                                           15    9605
>NP_689772
          Length = 245

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LICLTTKT 8
           L+CLTT+T
Sbjct: 162 LVCLTTRT 169
>NP_542158
          Length = 562

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 529 LVCLNTKT 536
>NP_001258297
          Length = 537

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 504 LVCLNTKT 511
>NP_000953
          Length = 599

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 566 LVCLNTKT 573
>NP_001258094
          Length = 490

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 457 LVCLNTKT 464
>NP_001258296
          Length = 453

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 420 LVCLNTKT 427
>NP_001258093
          Length = 551

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 518 LVCLNTKT 525
>NP_001258095
          Length = 453

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 420 LVCLNTKT 427
>XP_006717255
          Length = 537

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 504 LVCLNTKT 511
>XP_005252162
          Length = 574

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+CL TKT
Sbjct: 541 LVCLNTKT 548
>NP_054831
          Length = 1294

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 912 CLTTKTS 918
>NP_056137
          Length = 627

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LICLTTKT 8
           L+C++TKT
Sbjct: 450 LVCISTKT 457
>NP_001269832
          Length = 1287

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 905 CLTTKTS 911
>NP_001269831
          Length = 1285

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 903 CLTTKTS 909
>XP_005251106
          Length = 1281

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 899 CLTTKTS 905
>XP_006716688
          Length = 1294

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 912 CLTTKTS 918
>XP_006716687
          Length = 1294

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   CLTTKTA 9
           CLTTKT+
Sbjct: 912 CLTTKTS 918
>NP_005535
          Length = 1242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ICLTTKT 8
           +CLT+KT
Sbjct: 185 LCLTSKT 191
>XP_006712575
          Length = 1242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ICLTTKT 8
           +CLT+KT
Sbjct: 185 LCLTSKT 191
>XP_005246591
          Length = 1242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ICLTTKT 8
           +CLT+KT
Sbjct: 185 LCLTSKT 191
>NP_001275722
          Length = 116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          L+CL T+T
Sbjct: 8  LLCLDTRT 15
>XP_006720433
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ICLTTKT 8
           +C++TKT
Sbjct: 377 VCISTKT 383
>NP_997204
          Length = 480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LICLTTKT 8
           L+C T+KT
Sbjct: 375 LLCATSKT 382
>NP_000780
          Length = 1306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ICLTTKTA 9
           +CL  KTA
Sbjct: 156 VCLPNKTA 163
>NP_076435
          Length = 131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  CLTTKTA 9
          C+TT+T+
Sbjct: 46 CMTTRTS 52
>NP_001245200
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           + +TTKTA
Sbjct: 113 VTITTKTA 120
>NP_000240
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           + +TTKTA
Sbjct: 113 VTITTKTA 120
>NP_001161089
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ICLTTKTA 9
          + +TTKTA
Sbjct: 15 VTITTKTA 22
>NP_938205
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           +C+ T+TA
Sbjct: 495 VCIETETA 502
>NP_001171988
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>NP_078893
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>NP_001127860
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>NP_001127859
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>NP_060576
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>NP_001127861
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>NP_859064
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>NP_803430
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  CLTTKT 8
          C+TT+T
Sbjct: 46 CMTTRT 51
>NP_803429
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  CLTTKT 8
          C+TT+T
Sbjct: 46 CMTTRT 51
>NP_803252
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  CLTTKT 8
          C+TT+T
Sbjct: 46 CMTTRT 51
>NP_783863
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LICLTTKTA 9
           LIC   KTA
Sbjct: 621 LICSKNKTA 629
>NP_944489
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LICLTTKTA 9
           LIC   KTA
Sbjct: 570 LICSKNKTA 578
>NP_037413
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           +C+ T+TA
Sbjct: 495 VCIETETA 502
>XP_005260739
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           +C+ T+TA
Sbjct: 495 VCIETETA 502
>XP_005269276
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LICLTTKTA 9
           LIC   KTA
Sbjct: 518 LICSKNKTA 526
>XP_006719749
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LICLTTKTA 9
           LIC   KTA
Sbjct: 570 LICSKNKTA 578
>XP_005269275
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LICLTTKTA 9
           LIC   KTA
Sbjct: 621 LICSKNKTA 629
>XP_006717349
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_005252266
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_005252265
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_005252264
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_006717348
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_006717347
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_006717346
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CLTTK 7
           CLTTK
Sbjct: 417 CLTTK 421
>XP_005249851
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>XP_005249852
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>XP_005249853
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>XP_006715813
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>XP_005249850
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LICLTTKT 8
          LIC+ +KT
Sbjct: 20 LICVCSKT 27
>XP_005265218
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ICLTTKTA 9
           + +TTKTA
Sbjct: 113 VTITTKTA 120
>XP_005264228
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  ICLTTK 7
          ICL+TK
Sbjct: 63 ICLSTK 68
>XP_005264226
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>XP_006712018
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>XP_005264225
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>XP_005264224
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>XP_005264223
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ICLTTK 7
           ICL+TK
Sbjct: 122 ICLSTK 127
>NP_001035194
          Length = 4493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    ICLTTKT 8
            +C+TT+T
Sbjct: 4368 LCVTTET 4374
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.131    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 549,613
Number of extensions: 574
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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