Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              21     229
NP_671714                                                              21     229
XP_006715890                                                           21     229
XP_005250160                                                           21     229
XP_005250159                                                           21     229
NP_073739                                                              18    1935
XP_005272109                                                           18    1935
NP_954712                                                              17    2528
XP_006721827                                                           17    2528
XP_006721826                                                           17    2528
XP_006721825                                                           17    2528
NP_079321                                                              17    3301
XP_005261808                                                           17    3301
NP_004578                                                              17    4312
NP_001036041                                                           17    4312
XP_005253668                                                           16    5631
XP_005253667                                                           16    5631
XP_005253666                                                           16    5631
NP_076417                                                              16    5631
NP_002007                                                              16    7355
NP_001273206                                                           16    7355
NP_001273207                                                           16    7355
NP_001273208                                                           16    7355
NP_006313                                                              16    7355
NP_001027545                                                           16    7355
NP_060417                                                              16    7355
XP_005259285                                                           16    7355
XP_006723432                                                           16    7355
XP_006723431                                                           16    7355
XP_005259284                                                           16    7355
XP_006723430                                                           16    7355
XP_005259283                                                           16    7355
XP_005259282                                                           16    7355
XP_005259281                                                           16    7355
XP_005268350                                                           16    7355
NP_060292                                                              16    7355
NP_001027544                                                           16    7355
NP_057460                                                              15    9605
NP_001244928                                                           15    9605
NP_055990                                                              15    9605
NP_001129666                                                           15    9605
NP_001129665                                                           15    9605
NP_055616                                                              15    9605
NP_073752                                                              15    9605
XP_005259280                                                           15    9605
XP_005259279                                                           15    9605
XP_006721607                                                           15    9605
XP_005256736                                                           15    9605
XP_006720709                                                           15    9605
XP_005254660                                                           15    9605
XP_005265050                                                           15    9605
XP_005265049                                                           15    9605
XP_006713135                                                           15    9605
XP_006711879                                                           15    9605
XP_005273329                                                           15    9605
XP_005245194                                                           15    9605
NP_001131141                                                           15    9605
NP_055744                                                              15    9605
NP_037494                                                              15    9605
>NP_005742
          Length = 3907

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LHAQMQSSD 9
            LHAQ+QSSD
Sbjct: 3322 LHAQLQSSD 3330
>NP_671714
          Length = 3899

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LHAQMQSSD 9
            LHAQ+QSSD
Sbjct: 3314 LHAQLQSSD 3322
>XP_006715890
          Length = 3860

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LHAQMQSSD 9
            LHAQ+QSSD
Sbjct: 3275 LHAQLQSSD 3283
>XP_005250160
          Length = 3939

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LHAQMQSSD 9
            LHAQ+QSSD
Sbjct: 3354 LHAQLQSSD 3362
>XP_005250159
          Length = 3952

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LHAQMQSSD 9
            LHAQ+QSSD
Sbjct: 3367 LHAQLQSSD 3375
>NP_073739
          Length = 1430

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LHAQMQSSD 9
           LH+ MQ+SD
Sbjct: 661 LHSNMQTSD 669
>XP_005272109
          Length = 1123

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LHAQMQSSD 9
           LH+ MQ+SD
Sbjct: 661 LHSNMQTSD 669
>NP_954712
          Length = 1090

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LHAQMQSS 8
           LHAQ+QS+
Sbjct: 741 LHAQLQSA 748
>XP_006721827
          Length = 887

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LHAQMQSS 8
           LHAQ+QS+
Sbjct: 538 LHAQLQSA 545
>XP_006721826
          Length = 887

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LHAQMQSS 8
           LHAQ+QS+
Sbjct: 538 LHAQLQSA 545
>XP_006721825
          Length = 1071

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LHAQMQSS 8
           LHAQ+QS+
Sbjct: 722 LHAQLQSA 729
>NP_079321
          Length = 529

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LHAQMQS 7
           LHAQMQ+
Sbjct: 161 LHAQMQA 167
>XP_005261808
          Length = 529

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LHAQMQS 7
           LHAQMQ+
Sbjct: 161 LHAQMQA 167
>NP_004578
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LHAQMQSSD 9
           LH+++QSS+
Sbjct: 485 LHSKLQSSE 493
>NP_001036041
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LHAQMQSSD 9
           LH+++QSS+
Sbjct: 485 LHSKLQSSE 493
>XP_005253668
          Length = 420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LHAQMQSSD 9
           LH  M SSD
Sbjct: 317 LHGNMTSSD 325
>XP_005253667
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LHAQMQSSD 9
           LH  M SSD
Sbjct: 317 LHGNMTSSD 325
>XP_005253666
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LHAQMQSSD 9
           LH  M SSD
Sbjct: 317 LHGNMTSSD 325
>NP_076417
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LHAQMQSSD 9
           LH  M SSD
Sbjct: 317 LHGNMTSSD 325
>NP_002007
          Length = 4061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HAQMQSSD 9
            H Q+QS+D
Sbjct: 2008 HHQLQSAD 2015
>NP_001273206
          Length = 897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH+Q+Q  D
Sbjct: 332 LHSQLQLED 340
>NP_001273207
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH+Q+Q  D
Sbjct: 342 LHSQLQLED 350
>NP_001273208
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH+Q+Q  D
Sbjct: 342 LHSQLQLED 350
>NP_006313
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH+Q+Q  D
Sbjct: 342 LHSQLQLED 350
>NP_001027545
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>NP_060417
          Length = 888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+ +SD
Sbjct: 750 LHRQLNTSD 758
>XP_005259285
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_006723432
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_006723431
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_005259284
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_006723430
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_005259283
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_005259282
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_005259281
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>XP_005268350
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH+Q+Q  D
Sbjct: 342 LHSQLQLED 350
>NP_060292
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHAQMQSSD 9
           LHAQM+ ++
Sbjct: 99  LHAQMKKTN 107
>NP_001027544
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 269 LHQQLQSGE 277
>NP_057460
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH  +Q+SD
Sbjct: 876 LHVAVQNSD 884
>NP_001244928
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH  +Q+SD
Sbjct: 917 LHVAVQNSD 925
>NP_055990
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LHAQMQS 7
            LH Q+QS
Sbjct: 2179 LHVQLQS 2185
>NP_001129666
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HAQMQSSD 9
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
>NP_001129665
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HAQMQSSD 9
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
>NP_055616
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH ++ SSD
Sbjct: 343 LHQEVDSSD 351
>NP_073752
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHAQMQSS 8
           LH+Q+Q S
Sbjct: 835 LHSQIQES 842
>XP_005259280
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LHAQMQSSD 9
          LH Q+QS +
Sbjct: 82 LHQQLQSRE 90
>XP_005259279
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 165 LHQQLQSRE 173
>XP_006721607
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH  +Q+SD
Sbjct: 876 LHVAVQNSD 884
>XP_005256736
          Length = 1169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH  +Q+SD
Sbjct: 875 LHVAVQNSD 883
>XP_006720709
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHAQMQSS 8
           LH+Q+Q S
Sbjct: 564 LHSQIQES 571
>XP_005254660
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHAQMQSS 8
           LH+Q+Q S
Sbjct: 835 LHSQIQES 842
>XP_005265050
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LHAQMQS 7
            LH Q+QS
Sbjct: 1003 LHVQLQS 1009
>XP_005265049
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LHAQMQS 7
            LH Q+QS
Sbjct: 2145 LHVQLQS 2151
>XP_006713135
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LHAQMQS 7
            LH Q+QS
Sbjct: 2152 LHVQLQS 2158
>XP_006711879
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH ++ SSD
Sbjct: 343 LHQEVDSSD 351
>XP_005273329
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH ++ SSD
Sbjct: 140 LHQEVDSSD 148
>XP_005245194
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHAQMQSS 8
           LH +MQ+S
Sbjct: 857 LHQEMQNS 864
>NP_001131141
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHAQMQSS 8
           LH +MQ+S
Sbjct: 822 LHQEMQNS 829
>NP_055744
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HAQMQSSD 9
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
>NP_037494
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LHAQMQSSD 9
           LH Q+QS +
Sbjct: 165 LHQQLQSRE 173
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.109    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,050
Number of extensions: 784
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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