Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     390
NP_001185797                                                           17    4312
NP_005177                                                              17    4312
NP_001185798                                                           17    4312
NP_003296                                                              17    4312
NP_001124170                                                           17    4312
XP_006718761                                                           17    4312
XP_006714359                                                           17    4312
XP_006714358                                                           17    4312
NP_006421                                                              16    5631
NP_001243650                                                           16    5631
NP_859049                                                              16    5631
NP_001269781                                                           16    5631
NP_659449                                                              16    5631
NP_597702                                                              16    5631
NP_001269782                                                           16    5631
NP_001269783                                                           16    5631
NP_001135772                                                           16    5631
NP_001170936                                                           16    5631
XP_005252445                                                           16    5631
XP_006717455                                                           16    5631
XP_005246400                                                           16    5631
NP_689736                                                              16    5631
NP_115514                                                              16    5631
NP_690867                                                              16    5631
NP_000688                                                              16    7355
NP_001909                                                              16    7355
NP_004659                                                              16    7355
NP_001075019                                                           16    7355
NP_005558                                                              16    7355
NP_940931                                                              16    7355
XP_006724836                                                           16    7355
XP_005262507                                                           16    7355
XP_006724835                                                           16    7355
XP_006724834                                                           16    7355
XP_006724833                                                           16    7355
XP_006724832                                                           16    7355
XP_006724831                                                           16    7355
XP_006724830                                                           16    7355
XP_005262504                                                           16    7355
XP_006721943                                                           16    7355
XP_006721942                                                           16    7355
XP_006716232                                                           16    7355
XP_006716231                                                           16    7355
XP_005270603                                                           16    7355
XP_005270602                                                           16    7355
NP_001265318                                                           15    9605
NP_004685                                                              15    9605
NP_001167637                                                           15    9605
NP_001265317                                                           15    9605
NP_001265316                                                           15    9605
NP_444504                                                              15    9605
NP_001070952                                                           15    9605
NP_109599                                                              15    9605
NP_001136336                                                           15    9605
NP_001265319                                                           15    9605
XP_006722232                                                           15    9605
XP_005257846                                                           15    9605
XP_006721417                                                           15    9605
XP_006721416                                                           15    9605
XP_006715050                                                           15    9605
XP_006715049                                                           15    9605
XP_006715048                                                           15    9605
XP_006715047                                                           15    9605
XP_006710372                                                           15    9605
XP_005270458                                                           15    9605
XP_005270457                                                           15    9605
NP_008989                                                              15    9605
>NP_004295
          Length = 1620

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LGLLQFNLS 9
           +GLLQFNLS
Sbjct: 163 VGLLQFNLS 171
>NP_001185797
          Length = 714

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGLLQFNL 8
           LGL++FN+
Sbjct: 605 LGLVEFNI 612
>NP_005177
          Length = 714

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGLLQFNL 8
           LGL++FN+
Sbjct: 605 LGLVEFNI 612
>NP_001185798
          Length = 714

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGLLQFNL 8
           LGL++FN+
Sbjct: 605 LGLVEFNI 612
>NP_003296
          Length = 848

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LGLLQFNLS 9
           LGLL FN S
Sbjct: 397 LGLLVFNAS 405
>NP_001124170
          Length = 921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LGLLQFNLS 9
           LGLL FN S
Sbjct: 470 LGLLVFNAS 478
>XP_006718761
          Length = 714

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGLLQFNL 8
           LGL++FN+
Sbjct: 605 LGLVEFNI 612
>XP_006714359
          Length = 544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LGLLQFNLS 9
           LGLL FN S
Sbjct: 397 LGLLVFNAS 405
>XP_006714358
          Length = 820

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LGLLQFNLS 9
           LGLL FN S
Sbjct: 397 LGLLVFNAS 405
>NP_006421
          Length = 539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           +GL+QF LS
Sbjct: 246 IGLIQFCLS 254
>NP_001243650
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           +GL+QF LS
Sbjct: 216 IGLIQFCLS 224
>NP_859049
          Length = 287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 203 LELLQFNIN 211
>NP_001269781
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 232 LELLQFNIN 240
>NP_659449
          Length = 341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 257 LELLQFNIN 265
>NP_597702
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLLQFNLS 9
           GLL +NLS
Sbjct: 140 GLLPYNLS 147
>NP_001269782
          Length = 287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 203 LELLQFNIN 211
>NP_001269783
          Length = 208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 124 LELLQFNIN 132
>NP_001135772
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 226 LELLQFNIN 234
>NP_001170936
          Length = 998

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GLLQFNLS 9
           GLLQ NLS
Sbjct: 671 GLLQNNLS 678
>XP_005252445
          Length = 294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 210 LELLQFNIN 218
>XP_006717455
          Length = 317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 233 LELLQFNIN 241
>XP_005246400
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 277 LELLQFNIN 285
>NP_689736
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           L LLQFN++
Sbjct: 207 LELLQFNIN 215
>NP_115514
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LGLLQFN 7
           LGLLQF+
Sbjct: 602 LGLLQFD 608
>NP_690867
          Length = 674

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LGLLQFN 7
           LGLLQF+
Sbjct: 602 LGLLQFD 608
>NP_000688
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LGLLQF 6
          LGLLQF
Sbjct: 57 LGLLQF 62
>NP_001909
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGLLQF 6
           LGLLQF
Sbjct: 317 LGLLQF 322
>NP_004659
          Length = 1857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLLQFNL 8
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>NP_001075019
          Length = 1593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>NP_005558
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LQFNLS 9
           LQFNLS
Sbjct: 359 LQFNLS 364
>NP_940931
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGLLQFNL 8
            LG+L FN+
Sbjct: 1263 LGVLDFNI 1270
>XP_006724836
          Length = 1582

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_005262507
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724835
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724834
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724833
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724832
          Length = 1640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724831
          Length = 1640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724830
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_005262504
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLQFNL 8
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006721943
          Length = 1456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGLLQFNL 8
            LG+L FN+
Sbjct: 1263 LGVLDFNI 1270
>XP_006721942
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGLLQFNL 8
            LG+L FN+
Sbjct: 1263 LGVLDFNI 1270
>XP_006716232
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLLQFNL 8
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>XP_006716231
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLLQFNL 8
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>XP_005270603
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGLLQF 6
           LGLLQF
Sbjct: 136 LGLLQF 141
>XP_005270602
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGLLQF 6
           LGLLQF
Sbjct: 136 LGLLQF 141
>NP_001265318
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>NP_004685
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           +GLLQ N+
Sbjct: 186 VGLLQLNI 193
>NP_001167637
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           +GLLQ N+
Sbjct: 186 VGLLQLNI 193
>NP_001265317
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>NP_001265316
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>NP_444504
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           L LLQFN+
Sbjct: 310 LYLLQFNM 317
>NP_001070952
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>NP_109599
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>NP_001136336
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           LGL QF++S
Sbjct: 670 LGLEQFSVS 678
>NP_001265319
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LGLLQFNLS 9
          LG+  FNLS
Sbjct: 73 LGMSVFNLS 81
>XP_006722232
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           +GLLQ N+
Sbjct: 186 VGLLQLNI 193
>XP_005257846
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           +GLLQ N+
Sbjct: 186 VGLLQLNI 193
>XP_006721417
          Length = 2497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           LGL QF++S
Sbjct: 670 LGLEQFSVS 678
>XP_006721416
          Length = 2504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGLLQFNLS 9
           LGL QF++S
Sbjct: 653 LGLEQFSVS 661
>XP_006715050
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           LGLL+F +
Sbjct: 631 LGLLEFKI 638
>XP_006715049
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           LGLL+F +
Sbjct: 606 LGLLEFKI 613
>XP_006715048
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           LGLL+F +
Sbjct: 631 LGLLEFKI 638
>XP_006715047
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           LGLL+F +
Sbjct: 631 LGLLEFKI 638
>XP_006710372
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           L LLQFN+
Sbjct: 143 LYLLQFNM 150
>XP_005270458
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           L LLQFN+
Sbjct: 268 LYLLQFNM 275
>XP_005270457
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           L LLQFN+
Sbjct: 310 LYLLQFNM 317
>NP_008989
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGLLQFNL 8
           LGLL+F +
Sbjct: 630 LGLLEFKI 637
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.151    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 493,054
Number of extensions: 878
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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