Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           21     229
NP_004561                                                              21     229
XP_005253450                                                           21     229
XP_006719151                                                           21     229
NP_149109                                                              17    4312
NP_055543                                                              17    4312
NP_001271188                                                           17    4312
XP_006724587                                                           17    4312
XP_005274689                                                           17    4312
XP_006716465                                                           17    4312
NP_444256                                                              16    5631
NP_444254                                                              16    5631
NP_444253                                                              16    5631
NP_001017420                                                           16    5631
NP_444255                                                              16    5631
NP_689914                                                              16    5631
XP_006716360                                                           16    5631
XP_005247551                                                           16    5631
XP_005247550                                                           16    5631
XP_006713712                                                           16    5631
XP_005247549                                                           16    5631
NP_848648                                                              16    7355
NP_612815                                                              16    7355
NP_055259                                                              16    7355
NP_001273343                                                           16    7355
XP_006723908                                                           16    7355
XP_005260544                                                           16    7355
XP_005260543                                                           16    7355
XP_005260542                                                           16    7355
XP_005260540                                                           16    7355
XP_005260541                                                           16    7355
XP_006723907                                                           16    7355
XP_006723906                                                           16    7355
XP_005260538                                                           16    7355
XP_005260539                                                           16    7355
NP_000526                                                              15    9605
NP_036595                                                              15    9605
NP_570855                                                              15    9605
NP_570856                                                              15    9605
NP_065683                                                              15    9605
NP_002243                                                              15    9605
NP_001269357                                                           15    9605
NP_001123492                                                           15    9605
NP_001123493                                                           15    9605
NP_065998                                                              15    9605
NP_005168                                                              15    9605
XP_005257520                                                           15    9605
XP_005257518                                                           15    9605
XP_005257516                                                           15    9605
XP_005256134                                                           15    9605
XP_005256132                                                           15    9605
XP_006721303                                                           15    9605
XP_005256131                                                           15    9605
XP_006719381                                                           15    9605
XP_006719380                                                           15    9605
XP_005253620                                                           15    9605
XP_005250451                                                           15    9605
XP_005250450                                                           15    9605
XP_006715807                                                           15    9605
XP_006715806                                                           15    9605
XP_006715805                                                           15    9605
NP_003046                                                              15    9605
>NP_001275701
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LGFEQIVDE 9
          LGF+QIVDE
Sbjct: 38 LGFDQIVDE 46
>NP_004561
          Length = 1445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LGFEQIVDE 9
          LGF+QIVDE
Sbjct: 38 LGFDQIVDE 46
>XP_005253450
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LGFEQIVDE 9
          LGF+QIVDE
Sbjct: 38 LGFDQIVDE 46
>XP_006719151
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LGFEQIVDE 9
          LGF+QIVDE
Sbjct: 38 LGFDQIVDE 46
>NP_149109
          Length = 596

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FE+IVDE
Sbjct: 368 FERIVDE 374
>NP_055543
          Length = 1322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGFEQIVDE 9
           LG+E ++DE
Sbjct: 669 LGYETLLDE 677
>NP_001271188
          Length = 1820

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LGFEQIVD 8
           +GFE I+D
Sbjct: 673 VGFEDIID 680
>XP_006724587
          Length = 1732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGFEQIVDE 9
           LG+E ++DE
Sbjct: 639 LGYETLLDE 647
>XP_005274689
          Length = 1762

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGFEQIVDE 9
           LG+E ++DE
Sbjct: 669 LGYETLLDE 677
>XP_006716465
          Length = 1826

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GFEQIVDE 9
            GF Q+VD+
Sbjct: 1807 GFHQLVDQ 1814
>NP_444256
          Length = 1794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1478 FERIIDE 1484
>NP_444254
          Length = 1845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1478 FERIIDE 1484
>NP_444253
          Length = 1914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1547 FERIIDE 1553
>NP_001017420
          Length = 601

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGFEQIV 7
           LGF+Q+V
Sbjct: 463 LGFQQVV 469
>NP_444255
          Length = 1863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1547 FERIIDE 1553
>NP_689914
          Length = 5058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GFEQIVDE 9
            GF Q++DE
Sbjct: 1178 GFTQLLDE 1185
>XP_006716360
          Length = 601

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGFEQIV 7
           LGF+Q+V
Sbjct: 463 LGFQQVV 469
>XP_005247551
          Length = 1855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1488 FERIIDE 1494
>XP_005247550
          Length = 1856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1489 FERIIDE 1495
>XP_006713712
          Length = 1923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1557 FERIIDE 1563
>XP_005247549
          Length = 1924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FEQIVDE 9
            FE+I+DE
Sbjct: 1557 FERIIDE 1563
>NP_848648
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  GFEQIVD 8
          GF Q+VD
Sbjct: 23 GFSQLVD 29
>NP_612815
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>NP_055259
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FEQIVD 8
           FEQ+VD
Sbjct: 325 FEQVVD 330
>NP_001273343
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FEQIVD 8
           FEQ+VD
Sbjct: 325 FEQVVD 330
>XP_006723908
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260544
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260543
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260542
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260540
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260541
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_006723907
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_006723906
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260538
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>XP_005260539
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FEQIVDE 9
           FEQ+V+E
Sbjct: 123 FEQVVNE 129
>NP_000526
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GFEQIVDE 9
           GF+ ++DE
Sbjct: 750 GFDFVIDE 757
>NP_036595
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 378 GFQNIVD 384
>NP_570855
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 375 GFQNIVD 381
>NP_570856
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 375 GFQNIVD 381
>NP_065683
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 375 GFQNIVD 381
>NP_002243
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GFEQIVDE 9
          GF+Q VD+
Sbjct: 23 GFKQSVDQ 30
>NP_001269357
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GFEQIVDE 9
          GF+Q VD+
Sbjct: 23 GFKQSVDQ 30
>NP_001123492
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 380 GFQNIVD 386
>NP_001123493
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 373 GFQNIVD 379
>NP_065998
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GFE I+D
Sbjct: 241 GFESILD 247
>NP_005168
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 373 GFQNIVD 379
>XP_005257520
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 380 GFQNIVD 386
>XP_005257518
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 380 GFQNIVD 386
>XP_005257516
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 380 GFQNIVD 386
>XP_005256134
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GFE I+D
Sbjct: 279 GFESILD 285
>XP_005256132
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GFE I+D
Sbjct: 241 GFESILD 247
>XP_006721303
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GFE I+D
Sbjct: 241 GFESILD 247
>XP_005256131
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GFE I+D
Sbjct: 279 GFESILD 285
>XP_006719381
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 104 GFQNIVD 110
>XP_006719380
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 207 GFQNIVD 213
>XP_005253620
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 378 GFQNIVD 384
>XP_005250451
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 375 GFQNIVD 381
>XP_005250450
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GFEQIVD 8
           GF+ IVD
Sbjct: 375 GFQNIVD 381
>XP_006715807
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GFEQIVDE 9
           GF+ ++DE
Sbjct: 439 GFDFVIDE 446
>XP_006715806
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GFEQIVDE 9
           GF+ ++DE
Sbjct: 698 GFDFVIDE 705
>XP_006715805
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GFEQIVDE 9
           GF+ ++DE
Sbjct: 748 GFDFVIDE 755
>NP_003046
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LGFEQI 6
           LGFEQ+
Sbjct: 446 LGFEQL 451
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.150    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 523,715
Number of extensions: 1028
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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