Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              17    3301
NP_671714                                                              17    3301
NP_056013                                                              17    3301
NP_001274365                                                           17    3301
XP_006715890                                                           17    3301
XP_005250160                                                           17    3301
XP_005250159                                                           17    3301
XP_005271814                                                           17    3301
XP_005271813                                                           17    3301
XP_006715738                                                           17    3301
XP_005271812                                                           17    3301
XP_005271810                                                           17    3301
XP_005271809                                                           17    3301
XP_005271808                                                           17    3301
XP_005271807                                                           17    3301
NP_689991                                                              16    5631
NP_004590                                                              16    5631
NP_803136                                                              16    5631
NP_065880                                                              16    5631
NP_001129392                                                           16    5631
NP_001193486                                                           16    5631
XP_006724373                                                           16    5631
XP_005258593                                                           16    5631
XP_005251580                                                           16    5631
XP_005262954                                                           16    5631
XP_005262953                                                           16    5631
XP_005262950                                                           16    5631
NP_003299                                                              15    9605
NP_001073932                                                           15    9605
NP_001368                                                              15    9605
NP_001184171                                                           15    9605
NP_001161846                                                           15    9605
NP_001161849                                                           15    9605
NP_001161848                                                           15    9605
NP_057360                                                              15    9605
NP_001127812                                                           15    9605
NP_055829                                                              15    9605
NP_055624                                                              15    9605
NP_001230650                                                           15    9605
NP_001075949                                                           15    9605
NP_115678                                                              15    9605
NP_072095                                                              15    9605
NP_071423                                                              15    9605
NP_001248772                                                           15    9605
NP_001161847                                                           15    9605
NP_733794                                                              15    9605
NP_001186193                                                           15    9605
NP_001269398                                                           15    9605
XP_006725158                                                           15    9605
XP_002344239                                                           15    9605
XP_005272801                                                           15    9605
XP_005272800                                                           15    9605
XP_005272799                                                           15    9605
XP_005262626                                                           15    9605
XP_006718966                                                           15    9605
XP_006718329                                                           15    9605
XP_006718328                                                           15    9605
XP_006716771                                                           15    9605
XP_006715855                                                           15    9605
XP_006715351                                                           15    9605
XP_006715350                                                           15    9605
XP_006715349                                                           15    9605
XP_005249561                                                           15    9605
XP_006714730                                                           15    9605
XP_005272100                                                           15    9605
XP_005248564                                                           15    9605
NP_001157943                                                           15    9605
NP_005900                                                              15    9605
NP_055604                                                              15    9605
NP_001071165                                                           15    9605
>NP_005742
          Length = 3907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGERSVLLA 9
            L ERSVLLA
Sbjct: 3035 LEERSVLLA 3043
>NP_671714
          Length = 3899

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGERSVLLA 9
            L ERSVLLA
Sbjct: 3027 LEERSVLLA 3035
>NP_056013
          Length = 1261

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1148 GERSALLA 1155
>NP_001274365
          Length = 1271

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1205 GERSALLA 1212
>XP_006715890
          Length = 3860

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGERSVLLA 9
            L ERSVLLA
Sbjct: 2988 LEERSVLLA 2996
>XP_005250160
          Length = 3939

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGERSVLLA 9
            L ERSVLLA
Sbjct: 3067 LEERSVLLA 3075
>XP_005250159
          Length = 3952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGERSVLLA 9
            L ERSVLLA
Sbjct: 3080 LEERSVLLA 3088
>XP_005271814
          Length = 1047

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GERSVLLA 9
           GERS LLA
Sbjct: 934 GERSALLA 941
>XP_005271813
          Length = 1214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1148 GERSALLA 1155
>XP_006715738
          Length = 1229

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1163 GERSALLA 1170
>XP_005271812
          Length = 1245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1220 GERSALLA 1227
>XP_005271810
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1163 GERSALLA 1170
>XP_005271809
          Length = 1286

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1220 GERSALLA 1227
>XP_005271808
          Length = 1318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1205 GERSALLA 1212
>XP_005271807
          Length = 1333

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GERSVLLA 9
            GERS LLA
Sbjct: 1220 GERSALLA 1227
>NP_689991
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGERSVLL 8
           +GER++LL
Sbjct: 334 IGERAILL 341
>NP_004590
          Length = 1141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GERSVLLA 9
            G+R+VLLA
Sbjct: 1100 GQRAVLLA 1107
>NP_803136
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LGERSVLLA 9
          LGE  VLLA
Sbjct: 82 LGEAQVLLA 90
>NP_065880
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LGERSVLLA 9
           LGE+++LLA
Sbjct: 840 LGEQALLLA 848
>NP_001129392
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LGERSVLLA 9
           LGE+++LLA
Sbjct: 840 LGEQALLLA 848
>NP_001193486
          Length = 1386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LGERSVLLA 9
           LGE+++LLA
Sbjct: 803 LGEQALLLA 811
>XP_006724373
          Length = 1111

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GERSVLLA 9
            G+R+VLLA
Sbjct: 1070 GQRAVLLA 1077
>XP_005258593
          Length = 652

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LGERSVLLA 9
          LGE  VLLA
Sbjct: 82 LGEAQVLLA 90
>XP_005251580
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LGERSVLLA 9
           LGE+++LLA
Sbjct: 839 LGEQALLLA 847
>XP_005262954
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGERSVLL 8
           +GER++LL
Sbjct: 267 IGERAILL 274
>XP_005262953
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGERSVLL 8
           +GER++LL
Sbjct: 285 IGERAILL 292
>XP_005262950
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGERSVLL 8
           +GER++LL
Sbjct: 334 IGERAILL 341
>NP_003299
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>NP_001073932
          Length = 4314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GERSVLL 8
            GE+SVLL
Sbjct: 2919 GEQSVLL 2925
>NP_001368
          Length = 4307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GERSVLL 8
            GE+SVLL
Sbjct: 2919 GEQSVLL 2925
>NP_001184171
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>NP_001161846
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 220 LPERSVLL 227
>NP_001161849
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 229 LPERSVLL 236
>NP_001161848
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 184 LPERSVLL 191
>NP_057360
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           + ERSVLL
Sbjct: 141 MAERSVLL 148
>NP_001127812
          Length = 122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GERSVLLA 9
          G R+VLLA
Sbjct: 91 GNRAVLLA 98
>NP_055829
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGERSVLL 8
           +GE++VLL
Sbjct: 403 IGEKAVLL 410
>NP_055624
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 229 LPERSVLL 236
>NP_001230650
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>NP_001075949
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGERSV 6
           LGERSV
Sbjct: 482 LGERSV 487
>NP_115678
          Length = 122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GERSVLLA 9
          G R+VLLA
Sbjct: 91 GNRAVLLA 98
>NP_072095
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>NP_071423
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GERSVL 7
           GERSVL
Sbjct: 608 GERSVL 613
>NP_001248772
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGERSV 6
           LGERSV
Sbjct: 482 LGERSV 487
>NP_001161847
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 229 LPERSVLL 236
>NP_733794
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          + ERSVLL
Sbjct: 81 MAERSVLL 88
>NP_001186193
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          + ERSVLL
Sbjct: 81 MAERSVLL 88
>NP_001269398
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_006725158
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGERSV 6
           LGERSV
Sbjct: 482 LGERSV 487
>XP_002344239
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_005272801
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_005272800
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_005272799
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_005262626
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>XP_006718966
          Length = 4300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GERSVLL 8
            GE+SVLL
Sbjct: 2912 GEQSVLL 2918
>XP_006718329
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GERSVL 7
           GERSVL
Sbjct: 390 GERSVL 395
>XP_006718328
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GERSVL 7
           GERSVL
Sbjct: 390 GERSVL 395
>XP_006716771
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGERSV 6
           LGERSV
Sbjct: 482 LGERSV 487
>XP_006715855
          Length = 122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GERSVLLA 9
          G R+VLLA
Sbjct: 91 GNRAVLLA 98
>XP_006715351
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          L ERSVLL
Sbjct: 77 LPERSVLL 84
>XP_006715350
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 291 LPERSVLL 298
>XP_006715349
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 291 LPERSVLL 298
>XP_005249561
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LGERSVLL 8
           L ERSVLL
Sbjct: 291 LPERSVLL 298
>XP_006714730
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GERSVL 7
           GERSVL
Sbjct: 235 GERSVL 240
>XP_005272100
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GERSVL 7
           GERSVL
Sbjct: 580 GERSVL 585
>XP_005248564
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LGERSV 6
            LGERSV
Sbjct: 1146 LGERSV 1151
>NP_001157943
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
>NP_005900
          Length = 2468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LGERSV 6
            LGERSV
Sbjct: 1272 LGERSV 1277
>NP_055604
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LGERSV 6
           LGERSV
Sbjct: 522 LGERSV 527
>NP_001071165
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGERSVLL 8
          LGE +VLL
Sbjct: 59 LGEEAVLL 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.141    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 431,904
Number of extensions: 710
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package