Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              17    2528
XP_005262424                                                           17    2528
NP_542376                                                              17    4312
NP_004361                                                              17    4312
XP_006715397                                                           17    4312
NP_001121084                                                           16    5631
NP_000271                                                              16    5631
NP_001245394                                                           16    5631
NP_001165405                                                           16    5631
NP_001245393                                                           16    5631
NP_001165404                                                           16    5631
NP_071407                                                              16    5631
NP_001245391                                                           16    5631
NP_001245392                                                           16    5631
NP_001595                                                              16    5631
NP_817123                                                              16    5631
XP_005253015                                                           16    5631
XP_006718309                                                           16    5631
XP_006718308                                                           16    5631
XP_006718307                                                           16    5631
XP_005253014                                                           16    5631
XP_005253013                                                           16    5631
XP_005253012                                                           16    5631
XP_005253011                                                           16    5631
XP_006718005                                                           16    5631
XP_006718004                                                           16    5631
XP_006718003                                                           16    5631
XP_005275746                                                           16    5631
XP_003403671                                                           16    5631
XP_006710003                                                           16    5631
NP_001127925                                                           16    5631
NP_001136025                                                           16    7355
NP_001136024                                                           16    7355
NP_777576                                                              16    7355
NP_775925                                                              16    7355
NP_671766                                                              16    7355
NP_671756                                                              16    7355
NP_001265618                                                           16    7355
NP_003734                                                              16    7355
XP_005264801                                                           16    7355
XP_006713174                                                           16    7355
XP_005264800                                                           16    7355
XP_006712189                                                           16    7355
XP_005264685                                                           16    7355
XP_005264684                                                           16    7355
XP_005264683                                                           16    7355
XP_005264682                                                           16    7355
NP_000353                                                              15    9605
NP_001177793                                                           15    9605
NP_775922                                                              15    9605
NP_001269219                                                           15    9605
NP_068593                                                              15    9605
XP_006725678                                                           15    9605
XP_006725677                                                           15    9605
XP_006725676                                                           15    9605
XP_006725675                                                           15    9605
XP_006725674                                                           15    9605
XP_006725673                                                           15    9605
XP_006725672                                                           15    9605
XP_006725671                                                           15    9605
XP_005275699                                                           15    9605
XP_005275698                                                           15    9605
XP_006725325                                                           15    9605
XP_006725324                                                           15    9605
XP_006725323                                                           15    9605
XP_006725322                                                           15    9605
XP_006721813                                                           15    9605
XP_006721812                                                           15    9605
XP_005257185                                                           15    9605
XP_005257184                                                           15    9605
XP_006721811                                                           15    9605
XP_006721810                                                           15    9605
XP_006721809                                                           15    9605
XP_006721808                                                           15    9605
NP_954976                                                              15    9605
>NP_722576
          Length = 3080

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFSTSVYTV 9
            LFSTSV TV
Sbjct: 1128 LFSTSVDTV 1136
>XP_005262424
          Length = 2875

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           LFSTSV TV
Sbjct: 923 LFSTSVDTV 931
>NP_542376
          Length = 1899

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           LFS ++YTV
Sbjct: 460 LFSQTLYTV 468
>NP_004361
          Length = 3063

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LFSTSVYTV 9
            LFS ++YTV
Sbjct: 1624 LFSQTLYTV 1632
>XP_006715397
          Length = 2972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LFSTSVYTV 9
            LFS ++YTV
Sbjct: 1533 LFSQTLYTV 1541
>NP_001121084
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>NP_000271
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>NP_001245394
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>NP_001165405
          Length = 1079

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 274 FSTSVY 279
>NP_001245393
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>NP_001165404
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 274 FSTSVY 279
>NP_071407
          Length = 3354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2514 FSTSVY 2519
>NP_001245391
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 305 FSTSVY 310
>NP_001245392
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 305 FSTSVY 310
>NP_001595
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 305 FSTSVY 310
>NP_817123
          Length = 1040

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LFSTSVYT 8
           +FS SVYT
Sbjct: 156 VFSQSVYT 163
>XP_005253015
          Length = 286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 155 FSTSVY 160
>XP_006718309
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 224 FSTSVY 229
>XP_006718308
          Length = 369

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 238 FSTSVY 243
>XP_006718307
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 246 FSTSVY 251
>XP_005253014
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 305 FSTSVY 310
>XP_005253013
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>XP_005253012
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 291 FSTSVY 296
>XP_005253011
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSTSVY 7
           FSTSVY
Sbjct: 305 FSTSVY 310
>XP_006718005
          Length = 3397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2557 FSTSVY 2562
>XP_006718004
          Length = 3399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2559 FSTSVY 2564
>XP_006718003
          Length = 3419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2579 FSTSVY 2584
>XP_005275746
          Length = 3352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2512 FSTSVY 2517
>XP_003403671
          Length = 3354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2514 FSTSVY 2519
>XP_006710003
          Length = 3374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSTSVY 7
            FSTSVY
Sbjct: 2534 FSTSVY 2539
>NP_001127925
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LFSTSVYT 8
           +FS SVYT
Sbjct: 156 VFSQSVYT 163
>NP_001136025
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LFSTSVYTV 9
           LFST  YT+
Sbjct: 198 LFSTQGYTL 206
>NP_001136024
          Length = 1369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LFSTSVYTV 9
           LFST  YT+
Sbjct: 198 LFSTQGYTL 206
>NP_777576
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LFSTSVYTV 9
            LF+T++Y +
Sbjct: 1296 LFATTIYRI 1304
>NP_775925
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST VY V
Sbjct: 266 FSTDVYIV 273
>NP_671766
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>NP_671756
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>NP_001265618
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST VY V
Sbjct: 266 FSTDVYIV 273
>NP_003734
          Length = 1441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>XP_005264801
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST VY V
Sbjct: 266 FSTDVYIV 273
>XP_006713174
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST VY V
Sbjct: 266 FSTDVYIV 273
>XP_005264800
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST VY V
Sbjct: 266 FSTDVYIV 273
>XP_006712189
          Length = 1394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>XP_005264685
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>XP_005264684
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>XP_005264683
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>XP_005264682
          Length = 1441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSTSVYTV 9
           L +TSVY++
Sbjct: 151 LMNTSVYSI 159
>NP_000353
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  FSTSVYTV 9
          F T VYT+
Sbjct: 57 FGTLVYTI 64
>NP_001177793
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FSTSVYT 8
          FST+VY+
Sbjct: 22 FSTAVYS 28
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSTSVYT 8
           +FS+ VYT
Sbjct: 570 IFSSPVYT 577
>NP_001269219
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>NP_068593
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FSTSVYT 8
          FST+VY+
Sbjct: 22 FSTAVYS 28
>XP_006725678
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006725677
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006725676
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 330 FSTPEYTV 337
>XP_006725675
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 352 FSTPEYTV 359
>XP_006725674
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 495 FSTPEYTV 502
>XP_006725673
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 530 FSTPEYTV 537
>XP_006725672
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006725671
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_005275699
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 330 FSTPEYTV 337
>XP_005275698
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 352 FSTPEYTV 359
>XP_006725325
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 495 FSTPEYTV 502
>XP_006725324
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 530 FSTPEYTV 537
>XP_006725323
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006725322
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006721813
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006721812
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_005257185
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 330 FSTPEYTV 337
>XP_005257184
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 352 FSTPEYTV 359
>XP_006721811
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 495 FSTPEYTV 502
>XP_006721810
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 530 FSTPEYTV 537
>XP_006721809
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>XP_006721808
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 552 FSTPEYTV 559
>NP_954976
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FSTSVYTV 9
           FST  YTV
Sbjct: 211 FSTPEYTV 218
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.129    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,848
Number of extensions: 777
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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