Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
XP_006724407                                                           17    2528
XP_005261847                                                           17    2528
NP_001092764                                                           17    2528
NP_116202                                                              17    3301
NP_001073137                                                           17    3301
XP_005254137                                                           17    3301
XP_006720017                                                           17    3301
NP_056081                                                              17    4312
NP_001247420                                                           17    4312
XP_006723821                                                           17    4312
XP_006723820                                                           17    4312
XP_006723819                                                           17    4312
NP_006580                                                              16    5631
NP_001007528                                                           16    5631
XP_006726273                                                           16    5631
XP_006726272                                                           16    5631
XP_005276795                                                           16    5631
XP_006711190                                                           16    5631
XP_006711189                                                           16    5631
XP_005244902                                                           16    5631
NP_001229679                                                           16    5631
NP_009147                                                              16    7355
NP_852608                                                              16    7355
NP_852609                                                              16    7355
NP_004722                                                              16    7355
NP_001257552                                                           16    7355
NP_001257551                                                           16    7355
NP_000848                                                              16    7355
NP_115823                                                              16    7355
XP_005254318                                                           16    7355
XP_006722988                                                           16    7355
XP_006719756                                                           16    7355
XP_005269288                                                           16    7355
XP_005252821                                                           16    7355
XP_005252820                                                           16    7355
XP_005252819                                                           16    7355
XP_005252818                                                           16    7355
XP_005263016                                                           16    7355
NP_056122                                                              16    7355
NP_996816                                                              15    9605
NP_000121                                                              15    9605
NP_004870                                                              15    9605
NP_001277064                                                           15    9605
NP_001245250                                                           15    9605
NP_997724                                                              15    9605
NP_001123492                                                           15    9605
NP_001123493                                                           15    9605
NP_065835                                                              15    9605
NP_001245249                                                           15    9605
NP_001245251                                                           15    9605
NP_001245252                                                           15    9605
NP_006025                                                              15    9605
NP_115598                                                              15    9605
NP_071737                                                              15    9605
NP_001361                                                              15    9605
NP_060482                                                              15    9605
NP_878905                                                              15    9605
NP_005168                                                              15    9605
NP_001245253                                                           15    9605
XP_005257520                                                           15    9605
XP_005257518                                                           15    9605
XP_005257516                                                           15    9605
XP_005253286                                                           15    9605
XP_006718450                                                           15    9605
XP_005253284                                                           15    9605
XP_005265446                                                           15    9605
XP_005265445                                                           15    9605
XP_006712019                                                           15    9605
NP_005469                                                              15    9605
NP_001128350                                                           15    9605
>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFSILFSGI 9
            LFS LFSGI
Sbjct: 2808 LFSSLFSGI 2816
>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFSILFSGI 9
            LFS LFSGI
Sbjct: 2808 LFSSLFSGI 2816
>XP_006724407
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFSILFSGI 9
          LFS+LFS +
Sbjct: 15 LFSLLFSAV 23
>XP_005261847
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFSILFSGI 9
          LFS+LFS +
Sbjct: 15 LFSLLFSAV 23
>NP_001092764
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFSILFSGI 9
          LFS+LFS +
Sbjct: 15 LFSLLFSAV 23
>NP_116202
          Length = 760

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           +FS+LF G+
Sbjct: 144 VFSVLFGGL 152
>NP_001073137
          Length = 741

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           +FS+LF G+
Sbjct: 125 VFSVLFGGL 133
>XP_005254137
          Length = 632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           +FS+LF G+
Sbjct: 144 VFSVLFGGL 152
>XP_006720017
          Length = 741

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           +FS+LF G+
Sbjct: 125 VFSVLFGGL 133
>NP_056081
          Length = 581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           + +ILFSGI
Sbjct: 321 IMAILFSGI 329
>NP_001247420
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           + +ILFSGI
Sbjct: 337 IMAILFSGI 345
>XP_006723821
          Length = 334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFSILFSGI 9
          + +ILFSGI
Sbjct: 74 IMAILFSGI 82
>XP_006723820
          Length = 334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFSILFSGI 9
          + +ILFSGI
Sbjct: 74 IMAILFSGI 82
>XP_006723819
          Length = 614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           + +ILFSGI
Sbjct: 354 IMAILFSGI 362
>NP_006580
          Length = 668

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>NP_001007528
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           +S+LFSG+
Sbjct: 472 YSLLFSGM 479
>XP_006726273
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>XP_006726272
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>XP_005276795
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>XP_006711190
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>XP_006711189
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>XP_005244902
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+ FSG+
Sbjct: 74 FSLAFSGV 81
>NP_001229679
          Length = 245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LFSILFS 7
          LFSI+FS
Sbjct: 47 LFSIIFS 53
>NP_009147
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 330 FSILDSGI 337
>NP_852608
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 444 FSILDSGI 451
>NP_852609
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 330 FSILDSGI 337
>NP_004722
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           F+I+F+G+
Sbjct: 319 FAIMFNGV 326
>NP_001257552
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           F+I+F+G+
Sbjct: 319 FAIMFNGV 326
>NP_001257551
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           F+I+F+G+
Sbjct: 319 FAIMFNGV 326
>NP_000848
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SILFSGI 9
           +ILFSGI
Sbjct: 421 TILFSGI 427
>NP_115823
          Length = 2809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 296 FSVLFGG 302
>XP_005254318
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+L SG+
Sbjct: 33 FSVLLSGL 40
>XP_006722988
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 305 FSVLFGG 311
>XP_006719756
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           F+I+F+G+
Sbjct: 319 FAIMFNGV 326
>XP_005269288
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSILFSGI 9
           F+I+F+G+
Sbjct: 319 FAIMFNGV 326
>XP_005252821
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 330 FSILDSGI 337
>XP_005252820
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 330 FSILDSGI 337
>XP_005252819
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 444 FSILDSGI 451
>XP_005252818
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FSILFSGI 9
           FSIL SGI
Sbjct: 444 FSILDSGI 451
>XP_005263016
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SILFSGI 9
           +ILFSGI
Sbjct: 396 TILFSGI 402
>NP_056122
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FSILFSGI 9
          FS+L SG+
Sbjct: 72 FSVLLSGL 79
>NP_996816
          Length = 5202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SILFSGI 9
            S+LF+GI
Sbjct: 2362 SVLFTGI 2368
>NP_000121
          Length = 2224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           LFSI F+G
Sbjct: 266 LFSIHFNG 273
>NP_004870
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LFSILF 6
           LFSILF
Sbjct: 265 LFSILF 270
>NP_001277064
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LFSILF 6
           LFSILF
Sbjct: 251 LFSILF 256
>NP_001245250
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>NP_997724
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FSILFS 7
          FSILFS
Sbjct: 35 FSILFS 40
>NP_001123492
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 446 MFSTVFSG 453
>NP_001123493
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 439 MFSTVFSG 446
>NP_065835
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFSILFSGI 9
           LF++LFS +
Sbjct: 130 LFALLFSEV 138
>NP_001245249
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>NP_001245251
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>NP_001245252
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>NP_006025
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>NP_115598
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSILFS 7
           FSILFS
Sbjct: 678 FSILFS 683
>NP_071737
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 192 FSLLFEG 198
>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SILFSGI 9
            S+LF+GI
Sbjct: 2091 SVLFTGI 2097
>NP_060482
          Length = 2108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LFSILFSGI 9
           LF+  FSGI
Sbjct: 415 LFATSFSGI 423
>NP_878905
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 192 FSLLFEG 198
>NP_005168
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 439 MFSTVFSG 446
>NP_001245253
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>XP_005257520
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 446 MFSTVFSG 453
>XP_005257518
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 446 MFSTVFSG 453
>XP_005257516
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LFSILFSG 8
           +FS +FSG
Sbjct: 446 MFSTVFSG 453
>XP_005253286
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>XP_006718450
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>XP_005253284
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SILFSGI 9
          ++LFSGI
Sbjct: 70 AVLFSGI 76
>XP_005265446
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 225 FSLLFEG 231
>XP_005265445
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 225 FSLLFEG 231
>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SILFSGI 9
            S+LF+GI
Sbjct: 2091 SVLFTGI 2097
>NP_005469
          Length = 135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LFSILFS 7
          LFS+LF+
Sbjct: 10 LFSVLFA 16
>NP_001128350
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSILFSG 8
           FS+LF G
Sbjct: 192 FSLLFEG 198
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.165    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 414,896
Number of extensions: 829
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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