Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
NP_001265667                                                           17    2528
NP_057677                                                              17    2528
XP_005249228                                                           17    2528
NP_056121                                                              17    4312
XP_006710574                                                           17    4312
XP_005270746                                                           17    4312
NP_002110                                                              16    5631
XP_006726149                                                           16    5631
XP_005275597                                                           16    5631
XP_006726059                                                           16    5631
XP_005275440                                                           16    5631
XP_006725969                                                           16    5631
XP_005275300                                                           16    5631
XP_006725878                                                           16    5631
XP_005275163                                                           16    5631
XP_006725760                                                           16    5631
XP_005275008                                                           16    5631
XP_006725546                                                           16    5631
XP_005272861                                                           16    5631
XP_006715139                                                           16    5631
XP_005249104                                                           16    5631
NP_001120650                                                           15    9605
NP_001275980                                                           15    9605
NP_115655                                                              15    9605
NP_001243657                                                           15    9605
NP_001243656                                                           15    9605
NP_001243655                                                           15    9605
NP_001243654                                                           15    9605
NP_060203                                                              15    9605
NP_005119                                                              15    9605
NP_067050                                                              15    9605
NP_001275981                                                           15    9605
NP_001254747                                                           15    9605
NP_689919                                                              15    9605
NP_006581                                                              15    9605
XP_005275165                                                           15    9605
XP_005275010                                                           15    9605
XP_005261542                                                           15    9605
XP_006724131                                                           15    9605
XP_006713955                                                           15    9605
XP_005272341                                                           15    9605
XP_005272340                                                           15    9605
XP_005247886                                                           15    9605
XP_006713849                                                           15    9605
XP_006711986                                                           15    9605
XP_006711985                                                           15    9605
XP_005276137                                                           15    9605
XP_003120317                                                           15    9605
NP_777592                                                              15    9605
>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF LVQRSN
Sbjct: 15 LFTLVQRSN 23
>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF LVQRSN
Sbjct: 15 LFTLVQRSN 23
>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF LVQRSN
Sbjct: 34 LFTLVQRSN 42
>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF LVQRSN
Sbjct: 34 LFTLVQRSN 42
>NP_001265667
          Length = 449

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF+L+QR N
Sbjct: 17 LFLLLQRKN 25
>NP_057677
          Length = 469

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF+L+QR N
Sbjct: 17 LFLLLQRKN 25
>XP_005249228
          Length = 420

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          LF+L+QR N
Sbjct: 17 LFLLLQRKN 25
>NP_056121
          Length = 2620

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LFILVQRS 8
           LF+L+Q+S
Sbjct: 512 LFVLIQKS 519
>XP_006710574
          Length = 2445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LFILVQRS 8
           LF+L+Q+S
Sbjct: 337 LFVLIQKS 344
>XP_005270746
          Length = 2443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LFILVQRS 8
           LF+L+Q+S
Sbjct: 337 LFVLIQKS 344
>NP_002110
          Length = 250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006726149
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005275597
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006726059
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005275440
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006725969
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005275300
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006725878
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005275163
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006725760
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005275008
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006725546
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005272861
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>XP_006715139
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LFILVQRSN 9
          L ILV+RSN
Sbjct: 66 LDILVERSN 74
>XP_005249104
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L ILV+RSN
Sbjct: 96  LDILVERSN 104
>NP_001120650
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 708 VFVLVQR 714
>NP_001275980
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 619 VFVLVQR 625
>NP_115655
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FILVQR 7
           FILVQR
Sbjct: 990 FILVQR 995
>NP_001243657
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 167 MFLLVQR 173
>NP_001243656
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 192 MFLLVQR 198
>NP_001243655
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 270 MFLLVQR 276
>NP_001243654
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 270 MFLLVQR 276
>NP_060203
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 700 VFVLVQR 706
>NP_005119
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILVQRSN 9
           +LVQR+N
Sbjct: 240 VLVQRNN 246
>NP_067050
          Length = 149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FILVQRSN 9
           FI++ RSN
Sbjct: 101 FIILDRSN 108
>NP_001275981
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 575 VFVLVQR 581
>NP_001254747
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FILVQRSN 9
           FI++ RSN
Sbjct: 101 FIILDRSN 108
>NP_689919
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LFILVQRSN 9
          LF+ V RSN
Sbjct: 21 LFLQVPRSN 29
>NP_006581
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 270 MFLLVQR 276
>XP_005275165
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L IL++RSN
Sbjct: 95  LNILIKRSN 103
>XP_005275010
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L IL++RSN
Sbjct: 95  LNILIKRSN 103
>XP_005261542
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FILVQRSN 9
          F+L +RSN
Sbjct: 82 FVLPERSN 89
>XP_006724131
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILVQRSN 9
           +LVQR+N
Sbjct: 240 VLVQRNN 246
>XP_006713955
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 586 VFVLVQR 592
>XP_005272341
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 619 VFVLVQR 625
>XP_005272340
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFILVQR 7
           +F+LVQR
Sbjct: 638 VFVLVQR 644
>XP_005247886
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FILVQR 7
           FILVQR
Sbjct: 990 FILVQR 995
>XP_006713849
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FILVQR 7
           FILVQR
Sbjct: 941 FILVQR 946
>XP_006711986
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 LFILVQR 7
         +F+LVQR
Sbjct: 1 MFLLVQR 7
>XP_006711985
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 LFILVQR 7
         +F+LVQR
Sbjct: 1 MFLLVQR 7
>XP_005276137
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L IL++RSN
Sbjct: 95  LNILIKRSN 103
>XP_003120317
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFILVQRSN 9
           L IL++RSN
Sbjct: 95  LNILIKRSN 103
>NP_777592
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FILVQRSN 9
           F+L +RSN
Sbjct: 268 FVLPERSN 275
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.150    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,310
Number of extensions: 366
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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