Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
XP_006719294                                                           18    1935
NP_001138947                                                           18    1935
NP_852003                                                              17    3301
NP_938010                                                              17    3301
NP_938009                                                              17    3301
NP_689909                                                              17    3301
XP_005270670                                                           17    3301
XP_005270669                                                           17    3301
XP_006710506                                                           17    3301
XP_005270668                                                           17    3301
XP_005270667                                                           17    3301
XP_005270666                                                           17    3301
NP_659411                                                              17    3301
NP_079390                                                              17    4312
NP_597719                                                              17    4312
NP_001275511                                                           17    4312
XP_006719673                                                           17    4312
XP_005269218                                                           17    4312
XP_006719672                                                           17    4312
XP_005269215                                                           17    4312
XP_006713569                                                           17    4312
NP_001814                                                              16    5631
NP_006384                                                              16    5631
XP_005252401                                                           16    5631
XP_005252400                                                           16    5631
XP_005252399                                                           16    5631
NP_919268                                                              16    5631
NP_055227                                                              16    7355
NP_001005207                                                           16    7355
NP_001273674                                                           16    7355
NP_056109                                                              16    7355
NP_057107                                                              16    7355
XP_005257447                                                           16    7355
XP_005257446                                                           16    7355
XP_005257445                                                           16    7355
XP_005257444                                                           16    7355
XP_005257443                                                           16    7355
XP_005257442                                                           16    7355
NP_852091                                                              15    9605
NP_005025                                                              15    9605
NP_006297                                                              15    9605
NP_115791                                                              15    9605
NP_002044                                                              15    9605
NP_002069                                                              15    9605
NP_060754                                                              15    9605
NP_940931                                                              15    9605
NP_060217                                                              15    9605
NP_001138525                                                           15    9605
NP_065741                                                              15    9605
NP_001166184                                                           15    9605
XP_006721944                                                           15    9605
XP_006721943                                                           15    9605
XP_006721942                                                           15    9605
XP_006715859                                                           15    9605
XP_006715858                                                           15    9605
XP_006715857                                                           15    9605
XP_005265132                                                           15    9605
XP_005265131                                                           15    9605
XP_006713173                                                           15    9605
XP_005265130                                                           15    9605
XP_005265129                                                           15    9605
XP_005265128                                                           15    9605
XP_005265127                                                           15    9605
XP_005265126                                                           15    9605
XP_005270801                                                           15    9605
XP_005270800                                                           15    9605
XP_005270799                                                           15    9605
XP_005270798                                                           15    9605
XP_006710637                                                           15    9605
XP_006710636                                                           15    9605
NP_001268392                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LETQIKSKD 9
            LETQIKS+D
Sbjct: 2289 LETQIKSRD 2297
>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LETQIKSKD 9
            LETQIKS+D
Sbjct: 2084 LETQIKSRD 2092
>XP_006719294
          Length = 2348

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LE QIK+KD
Sbjct: 978 LERQIKTKD 986
>NP_001138947
          Length = 2351

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LE QIK+KD
Sbjct: 978 LERQIKTKD 986
>NP_852003
          Length = 816

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LETQIKSKD 9
          LET IKSK+
Sbjct: 53 LETGIKSKE 61
>NP_938010
          Length = 836

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LETQIKSKD 9
          LET IKSK+
Sbjct: 73 LETGIKSKE 81
>NP_938009
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 447 LETGIKSKE 455
>NP_689909
          Length = 1075

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 447 LETGIKSKE 455
>XP_005270670
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 447 LETGIKSKE 455
>XP_005270669
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 447 LETGIKSKE 455
>XP_006710506
          Length = 1247

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 518 LETGIKSKE 526
>XP_005270668
          Length = 1256

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 518 LETGIKSKE 526
>XP_005270667
          Length = 1280

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 518 LETGIKSKE 526
>XP_005270666
          Length = 1281

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           LET IKSK+
Sbjct: 518 LETGIKSKE 526
>NP_659411
          Length = 273

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  LETQIKS 7
          LETQIKS
Sbjct: 93 LETQIKS 99
>NP_079390
          Length = 2479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LETQIKSKD 9
            LETQ+K  D
Sbjct: 2388 LETQLKMSD 2396
>NP_597719
          Length = 770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETQIKSKD 9
           +TQIK KD
Sbjct: 568 KTQIKEKD 575
>NP_001275511
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETQIKSKD 9
           +TQIK KD
Sbjct: 568 KTQIKEKD 575
>XP_006719673
          Length = 1997

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LETQIKSKD 9
            LETQ+K  D
Sbjct: 1906 LETQLKMSD 1914
>XP_005269218
          Length = 2009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LETQIKSKD 9
            LETQ+K  D
Sbjct: 1918 LETQLKMSD 1926
>XP_006719672
          Length = 2510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LETQIKSKD 9
            LETQ+K  D
Sbjct: 2419 LETQLKMSD 2427
>XP_005269215
          Length = 2510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LETQIKSKD 9
            LETQ+K  D
Sbjct: 2419 LETQLKMSD 2427
>XP_006713569
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETQIKSKD 9
           +TQIK KD
Sbjct: 139 KTQIKEKD 146
>NP_001814
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETQIKSKD 9
           +ET  KSKD
Sbjct: 260 IETLFKSKD 268
>NP_006384
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETQIKSK 8
           LET+IK K
Sbjct: 490 LETEIKGK 497
>XP_005252401
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETQIKSK 8
           LET+IK K
Sbjct: 490 LETEIKGK 497
>XP_005252400
          Length = 933

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETQIKSK 8
           LET+IK K
Sbjct: 490 LETEIKGK 497
>XP_005252399
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETQIKSK 8
           LET+IK K
Sbjct: 456 LETEIKGK 463
>NP_919268
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETQIKSKD 9
           LE +IK KD
Sbjct: 327 LEQEIKDKD 335
>NP_055227
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LETQIKSK 8
          +ET+IK+K
Sbjct: 36 IETEIKNK 43
>NP_001005207
          Length = 964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>NP_001273674
          Length = 192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LETQIKSKD 9
          +E Q+K KD
Sbjct: 62 IEDQLKEKD 70
>NP_056109
          Length = 964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>NP_057107
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LETQIKSKD 9
           +E Q+K KD
Sbjct: 193 IEDQLKEKD 201
>XP_005257447
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>XP_005257446
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>XP_005257445
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>XP_005257444
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 159 LDTQLKNK 166
>XP_005257443
          Length = 939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 159 LDTQLKNK 166
>XP_005257442
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LETQIKSK 8
           L+TQ+K+K
Sbjct: 193 LDTQLKNK 200
>NP_852091
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LETQIK 6
           LETQIK
Sbjct: 501 LETQIK 506
>NP_005025
          Length = 58

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ETQIKSKD 9
          E +IKS+D
Sbjct: 25 ENEIKSRD 32
>NP_006297
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LETQIKSKD 9
           +E +IK KD
Sbjct: 280 IEKEIKEKD 288
>NP_115791
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+ Q+K+KD
Sbjct: 138 LQQQMKAKD 146
>NP_002044
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 461 LQTYLKSKE 469
>NP_002069
          Length = 2230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1516 LETELKSQ 1523
>NP_060754
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 459 LQTYLKSKE 467
>NP_940931
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETQIKSK 8
           ET++KSK
Sbjct: 103 ETELKSK 109
>NP_060217
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LETQIKSKD 9
            +ET +K+KD
Sbjct: 1410 VETIVKAKD 1418
>NP_001138525
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ETQIKSK 8
          ET++KSK
Sbjct: 47 ETELKSK 53
>NP_065741
          Length = 2617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LETQIKSKD 9
            +ET +K+KD
Sbjct: 1410 VETIVKAKD 1418
>NP_001166184
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1538 LETELKSQ 1545
>XP_006721944
          Length = 1232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETQIKSK 8
           ET++KSK
Sbjct: 103 ETELKSK 109
>XP_006721943
          Length = 1456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETQIKSK 8
           ET++KSK
Sbjct: 103 ETELKSK 109
>XP_006721942
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETQIKSK 8
           ET++KSK
Sbjct: 103 ETELKSK 109
>XP_006715859
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+ Q+K+KD
Sbjct: 138 LQQQMKAKD 146
>XP_006715858
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+ Q+K+KD
Sbjct: 138 LQQQMKAKD 146
>XP_006715857
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+ Q+K+KD
Sbjct: 138 LQQQMKAKD 146
>XP_005265132
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1500 LETELKSQ 1507
>XP_005265131
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1538 LETELKSQ 1545
>XP_006713173
          Length = 2250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1536 LETELKSQ 1543
>XP_005265130
          Length = 2252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1538 LETELKSQ 1545
>XP_005265129
          Length = 2269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1555 LETELKSQ 1562
>XP_005265128
          Length = 2278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1571 LETELKSQ 1578
>XP_005265127
          Length = 2283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1571 LETELKSQ 1578
>XP_005265126
          Length = 2285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LETQIKSK 8
            LET++KS+
Sbjct: 1571 LETELKSQ 1578
>XP_005270801
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 325 LQTYLKSKE 333
>XP_005270800
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 380 LQTYLKSKE 388
>XP_005270799
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 380 LQTYLKSKE 388
>XP_005270798
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 432 LQTYLKSKE 440
>XP_006710637
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 432 LQTYLKSKE 440
>XP_006710636
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LETQIKSKD 9
           L+T +KSK+
Sbjct: 327 LQTYLKSKE 335
>NP_001268392
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LETQIKSKD 9
           +E +IK KD
Sbjct: 258 IEKEIKEKD 266
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.118    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,998
Number of extensions: 924
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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