Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_001104582                                                           17    3301
NP_001104583                                                           17    3301
NP_005330                                                              17    3301
NP_003827                                                              17    4312
NP_060130                                                              17    4312
XP_005260019                                                           17    4312
XP_005260018                                                           17    4312
XP_005260017                                                           17    4312
XP_005260016                                                           17    4312
XP_005260015                                                           17    4312
XP_006722844                                                           17    4312
XP_005260014                                                           17    4312
XP_006722843                                                           17    4312
XP_005260013                                                           17    4312
XP_005260011                                                           17    4312
NP_060469                                                              16    5631
NP_001035351                                                           16    7355
NP_001035350                                                           16    7355
XP_005259216                                                           16    7355
XP_005262843                                                           16    7355
XP_005262842                                                           16    7355
NP_073589                                                              16    7355
NP_899236                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_001073883                                                           15    9605
NP_055517                                                              15    9605
NP_001036167                                                           15    9605
NP_065914                                                              15    9605
NP_001167628                                                           15    9605
NP_001276323                                                           15    9605
NP_001025110                                                           15    9605
NP_001161055                                                           15    9605
XP_005267748                                                           15    9605
XP_006715232                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
XP_005246686                                                           15    9605
XP_006712617                                                           15    9605
XP_005246684                                                           15    9605
XP_005246683                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2181 LETVTEALL 2189
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2202 LETVTEALL 2210
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2212 LETVTEALL 2220
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2212 LETVTEALL 2220
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2181 LETVTEALL 2189
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2191 LETVTEALL 2199
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2212 LETVTEALL 2220
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2199 LETVTEALL 2207
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2202 LETVTEALL 2210
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LETATEALL 9
            LET TEALL
Sbjct: 2212 LETVTEALL 2220
>NP_001104582
          Length = 157

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETATEALL 9
           +ETATE LL
Sbjct: 147 VETATELLL 155
>NP_001104583
          Length = 149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETATEALL 9
           +ETATE LL
Sbjct: 139 VETATELLL 147
>NP_005330
          Length = 200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LETATEALL 9
           +ETATE LL
Sbjct: 190 VETATELLL 198
>NP_003827
          Length = 383

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3 TATEALL 9
         TATEALL
Sbjct: 2 TATEALL 8
>NP_060130
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 127 ETSTEALM 134
>XP_005260019
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ETATEALL 9
          ET+TEAL+
Sbjct: 36 ETSTEALM 43
>XP_005260018
          Length = 634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 127 ETSTEALM 134
>XP_005260017
          Length = 634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 127 ETSTEALM 134
>XP_005260016
          Length = 634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 127 ETSTEALM 134
>XP_005260015
          Length = 634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 127 ETSTEALM 134
>XP_006722844
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 158 ETSTEALM 165
>XP_005260014
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 146 ETSTEALM 153
>XP_006722843
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 146 ETSTEALM 153
>XP_005260013
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 146 ETSTEALM 153
>XP_005260011
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ETATEALL 9
           ET+TEAL+
Sbjct: 158 ETSTEALM 165
>NP_060469
          Length = 1072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LETATEALL 9
            LETATE  L
Sbjct: 1026 LETATERYL 1034
>NP_001035351
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETATEALL 9
           +ETATE  L
Sbjct: 476 METATELFL 484
>NP_001035350
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETATEALL 9
           +ETATE  L
Sbjct: 459 METATELFL 467
>XP_005259216
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETATEAL 8
           +ETA EAL
Sbjct: 868 METAVEAL 875
>XP_005262843
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETATEALL 9
           +ETATE  L
Sbjct: 458 METATELFL 466
>XP_005262842
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LETATEALL 9
           +ETATE  L
Sbjct: 475 METATELFL 483
>NP_073589
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LETATEAL 8
           +ETA EAL
Sbjct: 868 METAVEAL 875
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 2196 LETKTQAL 2203
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 1870 LETKTQAL 1877
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 2374 LETKTQAL 2381
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 2236 LETKTQAL 2243
>NP_001073883
          Length = 2028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LETATE 6
           LETATE
Sbjct: 654 LETATE 659
>NP_055517
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETATE+ L
Sbjct: 571 ETATESAL 578
>NP_001036167
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETAT ALL
Sbjct: 238 ETATFALL 245
>NP_065914
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ETATEA 7
            ETATEA
Sbjct: 1078 ETATEA 1083
>NP_001167628
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ETATEA 7
            ETATEA
Sbjct: 1016 ETATEA 1021
>NP_001276323
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ETATEA 7
            ETATEA
Sbjct: 1066 ETATEA 1071
>NP_001025110
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ETATEA 7
            ETATEA
Sbjct: 1066 ETATEA 1071
>NP_001161055
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ETATEA 7
            ETATEA
Sbjct: 1066 ETATEA 1071
>XP_005267748
          Length = 1535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LETATE 6
           LETATE
Sbjct: 654 LETATE 659
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4282 LETKTQAL 4289
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 2407 LETKTQAL 2414
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 3956 LETKTQAL 3963
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4282 LETKTQAL 4289
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4308 LETKTQAL 4315
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4315 LETKTQAL 4322
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4322 LETKTQAL 4329
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4355 LETKTQAL 4362
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4493 LETKTQAL 4500
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4398 LETKTQAL 4405
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4460 LETKTQAL 4467
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4493 LETKTQAL 4500
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4493 LETKTQAL 4500
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4472 LETKTQAL 4479
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4493 LETKTQAL 4500
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LETATEAL 8
            LET T+AL
Sbjct: 4493 LETKTQAL 4500
>XP_005246686
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETAT ALL
Sbjct: 235 ETATFALL 242
>XP_006712617
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETAT ALL
Sbjct: 238 ETATFALL 245
>XP_005246684
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETAT ALL
Sbjct: 241 ETATFALL 248
>XP_005246683
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ETATEALL 9
           ETAT ALL
Sbjct: 273 ETATFALL 280
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.119    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,790
Number of extensions: 479
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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