Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              17    2528
XP_005271621                                                           17    2528
XP_006718907                                                           17    2528
XP_006718906                                                           17    2528
XP_005271619                                                           17    2528
XP_005271618                                                           17    2528
NP_002462                                                              17    4312
NP_000248                                                              17    4312
XP_005267753                                                           17    4312
XP_006720215                                                           17    4312
XP_006720214                                                           17    4312
XP_005267751                                                           17    4312
NP_078963                                                              15    9605
NP_001186131                                                           15    9605
NP_001186130                                                           15    9605
NP_055973                                                              15    9605
NP_001243805                                                           15    9605
NP_694856                                                              15    9605
NP_001243806                                                           15    9605
XP_006716810                                                           15    9605
XP_005251476                                                           15    9605
XP_005251475                                                           15    9605
XP_005251473                                                           15    9605
XP_005251474                                                           15    9605
XP_005251472                                                           15    9605
XP_005251471                                                           15    9605
XP_005251470                                                           15    9605
XP_006716809                                                           15    9605
XP_006716808                                                           15    9605
XP_006716807                                                           15    9605
XP_006716806                                                           15    9605
XP_005251468                                                           15    9605
XP_005251467                                                           15    9605
XP_005247836                                                           15    9605
XP_006713811                                                           15    9605
XP_006713810                                                           15    9605
XP_005247834                                                           15    9605

>NP_000042
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 472 LESSQKSDL 480



>XP_005271621
          Length = 2708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 124 LESSQKSDL 132



>XP_006718907
          Length = 3050

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 472 LESSQKSDL 480



>XP_006718906
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 472 LESSQKSDL 480



>XP_005271619
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 472 LESSQKSDL 480



>XP_005271618
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESSQKSAL 9
           LESSQKS L
Sbjct: 472 LESSQKSDL 480



>NP_002462
          Length = 1939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1469 LESSQKEA 1476



>NP_000248
          Length = 1935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1467 LESSQKEA 1474



>XP_005267753
          Length = 1935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1467 LESSQKEA 1474



>XP_006720215
          Length = 1968

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1498 LESSQKEA 1505



>XP_006720214
          Length = 1978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1508 LESSQKEA 1515



>XP_005267751
          Length = 1979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LESSQKSA 8
            LESSQK A
Sbjct: 1509 LESSQKEA 1516



>NP_078963
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 513 LESNQKS 519



>NP_001186131
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 484 LESNQKS 490



>NP_001186130
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 513 LESNQKS 519



>NP_055973
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>NP_001243805
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>NP_694856
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>NP_001243806
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>XP_006716810
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251476
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251475
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251473
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251474
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251472
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251471
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSQKSAL 9
           SSQKSA+
Sbjct: 968 SSQKSAI 974



>XP_005251470
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1046 SSQKSAI 1052



>XP_006716809
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1108 SSQKSAI 1114



>XP_006716808
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1108 SSQKSAI 1114



>XP_006716807
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>XP_006716806
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>XP_005251468
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>XP_005251467
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSQKSAL 9
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132



>XP_005247836
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 301 LESNQKS 307



>XP_006713811
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 513 LESNQKS 519



>XP_006713810
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 512 LESNQKS 518



>XP_005247834
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESSQKS 7
           LES+QKS
Sbjct: 513 LESNQKS 519



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.283   0.0990    0.202 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 229,253
Number of extensions: 172
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)