Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_919047                                                              18    1482
XP_005250598                                                           18    1482
NP_000687                                                              17    3301
NP_060105                                                              17    3301
XP_005274094                                                           17    3301
XP_006718644                                                           17    3301
XP_005274093                                                           17    3301
XP_005274092                                                           17    3301
NP_005874                                                              16    5631
XP_006722673                                                           16    5631
XP_006722672                                                           16    5631
XP_006722671                                                           16    5631
XP_006722670                                                           16    5631
XP_005259532                                                           16    5631
NP_054733                                                              16    7355
NP_443099                                                              16    7355
NP_004000                                                              16    7355
NP_004001                                                              16    7355
NP_003997                                                              16    7355
NP_000100                                                              16    7355
NP_001034456                                                           16    7355
NP_001034455                                                           16    7355
NP_001687                                                              16    7355
NP_542384                                                              16    7355
XP_006724538                                                           16    7355
XP_006724537                                                           16    7355
XP_006724536                                                           16    7355
XP_006724535                                                           16    7355
XP_006724534                                                           16    7355
XP_006724533                                                           16    7355
XP_006724532                                                           16    7355
XP_006724531                                                           16    7355
XP_006720008                                                           16    7355
XP_006720007                                                           16    7355
XP_006720006                                                           16    7355
XP_005248564                                                           16    7355
XP_005264691                                                           16    7355
XP_005264690                                                           16    7355
NP_005900                                                              16    7355
NP_055281                                                              15    9605
NP_006720                                                              15    9605
NP_009293                                                              15    9605
NP_037498                                                              15    9605
NP_009120                                                              15    9605
NP_002239                                                              15    9605
NP_001244088                                                           15    9605
NP_008949                                                              15    9605
NP_005683                                                              15    9605
XP_006724172                                                           15    9605
XP_006724171                                                           15    9605
XP_006724170                                                           15    9605
XP_005259964                                                           15    9605
XP_005259963                                                           15    9605
XP_005259962                                                           15    9605
XP_006717007                                                           15    9605
XP_006717005                                                           15    9605
XP_006717004                                                           15    9605
XP_006717003                                                           15    9605
XP_005251736                                                           15    9605
XP_006715887                                                           15    9605
XP_005249988                                                           15    9605
XP_005270810                                                           15    9605
NP_056089                                                              15    9605
NP_689449                                                              15    9605
>NP_919047
          Length = 520

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           LESR DVDL
Sbjct: 465 LESRPDVDL 473
>XP_005250598
          Length = 457

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           LESR DVDL
Sbjct: 402 LESRPDVDL 410
>NP_000687
          Length = 518

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ESRLDVDL 9
           E+RLD+D+
Sbjct: 129 EARLDIDI 136
>NP_060105
          Length = 885

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LESRLDVD 8
           LESR++VD
Sbjct: 809 LESRMEVD 816
>XP_005274094
          Length = 713

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LESRLDVD 8
           LESR++VD
Sbjct: 637 LESRMEVD 644
>XP_006718644
          Length = 862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LESRLDVD 8
           LESR++VD
Sbjct: 786 LESRMEVD 793
>XP_005274093
          Length = 862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LESRLDVD 8
           LESR++VD
Sbjct: 786 LESRMEVD 793
>XP_005274092
          Length = 885

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LESRLDVD 8
           LESR++VD
Sbjct: 809 LESRMEVD 816
>NP_005874
          Length = 2303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 965 SRLDLDL 971
>XP_006722673
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 964 SRLDLDL 970
>XP_006722672
          Length = 2303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 965 SRLDLDL 971
>XP_006722671
          Length = 2303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 965 SRLDLDL 971
>XP_006722670
          Length = 2326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 988 SRLDLDL 994
>XP_005259532
          Length = 2327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SRLDVDL 9
           SRLD+DL
Sbjct: 989 SRLDLDL 995
>NP_054733
          Length = 2136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ESRLDVDL 9
           +SR+D DL
Sbjct: 384 QSRMDTDL 391
>NP_443099
          Length = 1738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LESRLDVDL 9
            L  RL+VDL
Sbjct: 1497 LRGRLEVDL 1505
>NP_004000
          Length = 3681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 716 IRKRLDVDI 724
>NP_004001
          Length = 3562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 597 IRKRLDVDI 605
>NP_003997
          Length = 3685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>NP_000100
          Length = 3677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 712 IRKRLDVDI 720
>NP_001034456
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 166 LESRLDL 172
>NP_001034455
          Length = 204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 174 LESRLDL 180
>NP_001687
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 196 LESRLDL 202
>NP_542384
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 196 LESRLDL 202
>XP_006724538
          Length = 3575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006724537
          Length = 3593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006724536
          Length = 3657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006724535
          Length = 3660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 677 IRKRLDVDI 685
>XP_006724534
          Length = 3668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006724533
          Length = 3690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006724532
          Length = 3695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 712 IRKRLDVDI 720
>XP_006724531
          Length = 3703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           +  RLDVD+
Sbjct: 720 IRKRLDVDI 728
>XP_006720008
          Length = 1645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LESRLDVDL 9
            L  RL+VDL
Sbjct: 1404 LRGRLEVDL 1412
>XP_006720007
          Length = 1709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LESRLDVDL 9
            L  RL+VDL
Sbjct: 1468 LRGRLEVDL 1476
>XP_006720006
          Length = 1713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LESRLDVDL 9
            L  RL+VDL
Sbjct: 1472 LRGRLEVDL 1480
>XP_005248564
          Length = 2342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ESRLDVDL 9
            E+R DVDL
Sbjct: 1949 EARQDVDL 1956
>XP_005264691
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 196 LESRLDL 202
>XP_005264690
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LESRLDV 7
           LESRLD+
Sbjct: 196 LESRLDL 202
>NP_005900
          Length = 2468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ESRLDVDL 9
            E+R DVDL
Sbjct: 2075 EARQDVDL 2082
>NP_055281
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ESRLDVDL 9
           ESR D+D+
Sbjct: 121 ESRRDIDV 128
>NP_006720
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RLDVDL 9
           RLD+DL
Sbjct: 472 RLDIDL 477
>NP_009293
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RLDVDL 9
           RLD+DL
Sbjct: 472 RLDIDL 477
>NP_037498
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 118 LESRLD 123
>NP_009120
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           L+ +LD+DL
Sbjct: 469 LQEQLDLDL 477
>NP_002239
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 485 LESRLD 490
>NP_001244088
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LESRLDVD 8
          ++SRLD D
Sbjct: 26 IKSRLDTD 33
>NP_008949
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 574 LESRLD 579
>NP_005683
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           L+ +LD+DL
Sbjct: 469 LQEQLDLDL 477
>XP_006724172
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           L  RLD+DL
Sbjct: 194 LSFRLDLDL 202
>XP_006724171
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           L  RLD+DL
Sbjct: 194 LSFRLDLDL 202
>XP_006724170
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           L  RLD+DL
Sbjct: 194 LSFRLDLDL 202
>XP_005259964
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 565 LESRLD 570
>XP_005259963
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 568 LESRLD 573
>XP_005259962
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 571 LESRLD 576
>XP_006717007
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 574 LESRLD 579
>XP_006717005
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LESRLD 6
          LESRLD
Sbjct: 22 LESRLD 27
>XP_006717004
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 574 LESRLD 579
>XP_006717003
          Length = 2278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 574 LESRLD 579
>XP_005251736
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LESRLD 6
           LESRLD
Sbjct: 574 LESRLD 579
>XP_006715887
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           L+ +LD+DL
Sbjct: 469 LQEQLDLDL 477
>XP_005249988
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LESRLDVDL 9
           L+ +LD+DL
Sbjct: 469 LQEQLDLDL 477
>XP_005270810
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ESRLDVDL 9
           ESR D+D+
Sbjct: 121 ESRRDIDV 128
>NP_056089
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           L SR+D DL
Sbjct: 172 LGSRIDYDL 180
>NP_689449
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LESRLDVDL 9
           L  RLD+DL
Sbjct: 194 LSFRLDLDL 202
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.144    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,829
Number of extensions: 492
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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