Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           17    2528
NP_001185763                                                           17    2528
NP_055459                                                              17    2528
XP_006726410                                                           17    2528
XP_006711719                                                           17    2528
XP_006711718                                                           17    2528
XP_006711717                                                           17    2528
XP_006711716                                                           17    2528
XP_006711715                                                           17    2528
XP_006711714                                                           17    2528
XP_006711713                                                           17    2528
XP_006711712                                                           17    2528
XP_006711711                                                           17    2528
XP_006711710                                                           17    2528
XP_006711709                                                           17    2528
XP_005277503                                                           17    2528
XP_005273038                                                           17    2528
XP_006711708                                                           17    2528
XP_005277500                                                           17    2528
XP_006711707                                                           17    2528
XP_005277499                                                           17    2528
XP_006711706                                                           17    2528
XP_006711705                                                           17    2528
XP_006711164                                                           17    2528
XP_006710143                                                           17    2528
XP_006710142                                                           17    2528
XP_006710141                                                           17    2528
NP_060427                                                              16    5631
XP_005260069                                                           16    5631
XP_005260067                                                           16    5631
XP_005260066                                                           16    5631
XP_006722891                                                           16    5631
XP_005260065                                                           16    5631
XP_005260063                                                           16    5631
XP_005260061                                                           16    5631
NP_001171588                                                           16    7355
NP_004888                                                              16    7355
NP_114408                                                              16    7355
NP_001152758                                                           16    7355
NP_945314                                                              16    7355
XP_006718141                                                           16    7355
NP_056069                                                              15    9605
NP_001121186                                                           15    9605
NP_078779                                                              15    9605
NP_006725                                                              15    9605
XP_005269610                                                           15    9605
XP_006716380                                                           15    9605
XP_006716379                                                           15    9605
XP_005273516                                                           15    9605
XP_005273515                                                           15    9605
XP_005267014                                                           15    9605
XP_006710872                                                           15    9605
XP_006710871                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1518 LEPLALRLS 1526
>NP_001185763
          Length = 2362

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1562 LEPLALRLS 1570
>NP_055459
          Length = 2346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1562 LEPLALRLS 1570
>XP_006726410
          Length = 2087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1365 LEPLALRLS 1373
>XP_006711719
          Length = 2302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1518 LEPLALRLS 1526
>XP_006711718
          Length = 1436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LE LALRLS
Sbjct: 569 LEPLALRLS 577
>XP_006711717
          Length = 2385

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1518 LEPLALRLS 1526
>XP_006711716
          Length = 2411

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1627 LEPLALRLS 1635
>XP_006711715
          Length = 2428

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1561 LEPLALRLS 1569
>XP_006711714
          Length = 2429

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1562 LEPLALRLS 1570
>XP_006711713
          Length = 2432

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1565 LEPLALRLS 1573
>XP_006711712
          Length = 2473

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_006711711
          Length = 2482

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1615 LEPLALRLS 1623
>XP_006711710
          Length = 2494

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1627 LEPLALRLS 1635
>XP_006711709
          Length = 2495

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1628 LEPLALRLS 1636
>XP_005277503
          Length = 2498

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_005273038
          Length = 2509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_006711708
          Length = 2512

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_005277500
          Length = 2525

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_006711707
          Length = 2553

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_005277499
          Length = 2561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_006711706
          Length = 2591

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1724 LEPLALRLS 1732
>XP_006711705
          Length = 2592

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1725 LEPLALRLS 1733
>XP_006711164
          Length = 2087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LEQLALRLS 9
            LE LALRLS
Sbjct: 1365 LEPLALRLS 1373
>XP_006710143
          Length = 562

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LE LALRLS
Sbjct: 404 LEPLALRLS 412
>XP_006710142
          Length = 671

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LE LALRLS
Sbjct: 513 LEPLALRLS 521
>XP_006710141
          Length = 672

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LE LALRLS
Sbjct: 514 LEPLALRLS 522
>NP_060427
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   QLALRLS 9
           QLALRLS
Sbjct: 242 QLALRLS 248
>XP_005260069
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LEQLALRLS 9
          LEQ+A RLS
Sbjct: 22 LEQVASRLS 30
>XP_005260067
          Length = 968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LEQLALRLS 9
          LEQ+A RLS
Sbjct: 22 LEQVASRLS 30
>XP_005260066
          Length = 968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LEQLALRLS 9
          LEQ+A RLS
Sbjct: 22 LEQVASRLS 30
>XP_006722891
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LEQ+A RLS
Sbjct: 169 LEQVASRLS 177
>XP_005260065
          Length = 1152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LEQ+A RLS
Sbjct: 206 LEQVASRLS 214
>XP_005260063
          Length = 1756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LEQ+A RLS
Sbjct: 943 LEQVASRLS 951
>XP_005260061
          Length = 1889

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           LEQ+A RLS
Sbjct: 943 LEQVASRLS 951
>NP_001171588
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           + QLALRL+
Sbjct: 154 MRQLALRLA 162
>NP_004888
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           + QLALRL+
Sbjct: 154 MRQLALRLA 162
>NP_114408
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LEQLALRLS 9
          LEQ  LRLS
Sbjct: 43 LEQRCLRLS 51
>NP_001152758
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LEQLALRLS 9
          LEQ  LRLS
Sbjct: 43 LEQRCLRLS 51
>NP_945314
          Length = 1386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LEQLALRL 8
            LEQL LR+
Sbjct: 999  LEQLCLRI 1006
>XP_006718141
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LEQLALRLS 9
           + QLALRL+
Sbjct: 154 MRQLALRLA 162
>NP_056069
          Length = 1826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LEQLALRLS 9
           LEQL  RLS
Sbjct: 637 LEQLRRRLS 645
>NP_001121186
          Length = 2405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>NP_078779
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>NP_006725
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 367 QKLALRLS 374
>XP_005269610
          Length = 143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LEQLALRL 8
          L+QLAL+L
Sbjct: 49 LQQLALQL 56
>XP_006716380
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LEQLALRLS 9
           LEQL  RLS
Sbjct: 573 LEQLRRRLS 581
>XP_006716379
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LEQLALRLS 9
           LEQL  RLS
Sbjct: 573 LEQLRRRLS 581
>XP_005273516
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LEQLALRLS 9
           LEQL  RLS
Sbjct: 573 LEQLRRRLS 581
>XP_005273515
          Length = 1805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LEQLALRLS 9
           LEQL  RLS
Sbjct: 637 LEQLRRRLS 645
>XP_005267014
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 367 QKLALRLS 374
>XP_006710872
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>XP_006710871
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQLALRLS 9
           ++LALRLS
Sbjct: 362 QKLALRLS 369
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.137    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 382,263
Number of extensions: 509
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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