Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726436                                                           18    1482
XP_006726410                                                           18    1482
XP_006711784                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_005276114                                                           18    1482
XP_006710122                                                           18    1482
NP_005362                                                              17    3301
XP_005268930                                                           17    3301
NP_001934                                                              17    4312
NP_079390                                                              16    5631
NP_001129243                                                           16    5631
NP_817123                                                              16    5631
NP_002942                                                              16    5631
XP_006723915                                                           16    5631
XP_006723914                                                           16    5631
XP_005260548                                                           16    5631
XP_006723913                                                           16    5631
XP_006723912                                                           16    5631
XP_006719673                                                           16    5631
XP_005269218                                                           16    5631
XP_005269217                                                           16    5631
XP_006719672                                                           16    5631
XP_005269215                                                           16    5631
NP_001127925                                                           16    5631
NP_060788                                                              16    7355
NP_055931                                                              16    7355
NP_001157683                                                           16    7355
NP_612208                                                              16    7355
NP_001257810                                                           16    7355
NP_001257809                                                           16    7355
NP_001157685                                                           16    7355
XP_005253473                                                           16    7355
XP_005253472                                                           16    7355
XP_005253471                                                           16    7355
XP_005253470                                                           16    7355
XP_006719168                                                           16    7355
XP_006719167                                                           16    7355
XP_006719166                                                           16    7355
XP_006714056                                                           16    7355
XP_005248108                                                           16    7355
XP_005248109                                                           16    7355
XP_006714055                                                           16    7355
NP_001248348                                                           15    9605
NP_004624                                                              15    9605
XP_006712799                                                           15    9605
XP_006712798                                                           15    9605
XP_006712797                                                           15    9605
XP_006712796                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2174 LELRTKVSK 2182
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2280 LELRTKVSK 2288
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2280 LELRTKVSK 2288
>XP_006726436
          Length = 178

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LELRIKVSK 9
          LELR KVSK
Sbjct: 58 LELRTKVSK 66
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2021 LELRTKVSK 2029
>XP_006711784
          Length = 178

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LELRIKVSK 9
          LELR KVSK
Sbjct: 58 LELRTKVSK 66
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2236 LELRTKVSK 2244
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 1287 LELRTKVSK 1295
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2236 LELRTKVSK 2244
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2345 LELRTKVSK 2353
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2279 LELRTKVSK 2287
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2280 LELRTKVSK 2288
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2283 LELRTKVSK 2291
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2324 LELRTKVSK 2332
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2333 LELRTKVSK 2341
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2345 LELRTKVSK 2353
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2346 LELRTKVSK 2354
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2443 LELRTKVSK 2451
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2443 LELRTKVSK 2451
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2363 LELRTKVSK 2371
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2443 LELRTKVSK 2451
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2404 LELRTKVSK 2412
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2443 LELRTKVSK 2451
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2442 LELRTKVSK 2450
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2443 LELRTKVSK 2451
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELRIKVSK 9
            LELR KVSK
Sbjct: 2021 LELRTKVSK 2029
>XP_005276114
          Length = 134

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LELRIKVSK 9
          LELR KVSK
Sbjct: 28 LELRTKVSK 36
>XP_006710122
          Length = 126

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LELRIKVSK 9
          LELR KVSK
Sbjct: 58 LELRTKVSK 66
>NP_005362
          Length = 276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           LE+R+KVS
Sbjct: 106 LEIRVKVS 113
>XP_005268930
          Length = 233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LELRIKVS 8
          LE+R+KVS
Sbjct: 63 LEIRVKVS 70
>NP_001934
          Length = 1118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LELRIKV 7
           LELRIKV
Sbjct: 143 LELRIKV 149
>NP_079390
          Length = 2479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LELRIKVSK 9
            +EL+++VSK
Sbjct: 1146 MELKVEVSK 1154
>NP_001129243
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 331 VELRVKIS 338
>NP_817123
          Length = 1040

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELRIKV 7
           LELR+KV
Sbjct: 141 LELRVKV 147
>NP_002942
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 363 VELRVKIS 370
>XP_006723915
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_006723914
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_005260548
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 363 VELRVKIS 370
>XP_006723913
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_006723912
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_006719673
          Length = 1997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           +EL+++VSK
Sbjct: 664 MELKVEVSK 672
>XP_005269218
          Length = 2009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           +EL+++VSK
Sbjct: 676 MELKVEVSK 684
>XP_005269217
          Length = 2353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LELRIKVSK 9
            +EL+++VSK
Sbjct: 1177 MELKVEVSK 1185
>XP_006719672
          Length = 2510

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LELRIKVSK 9
            +EL+++VSK
Sbjct: 1177 MELKVEVSK 1185
>XP_005269215
          Length = 2510

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LELRIKVSK 9
            +EL+++VSK
Sbjct: 1177 MELKVEVSK 1185
>NP_001127925
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELRIKV 7
           LELR+KV
Sbjct: 141 LELRVKV 147
>NP_060788
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 141 LEIKLKVSE 149
>NP_055931
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +E+R+KVS
Sbjct: 590 IEMRLKVS 597
>NP_001157683
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +E+R+KVS
Sbjct: 625 IEMRLKVS 632
>NP_612208
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 245 LELRVKTVK 253
>NP_001257810
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 175 LELRVKTVK 183
>NP_001257809
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 211 LELRVKTVK 219
>NP_001157685
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LELRIKVS 8
           +E+R+KVS
Sbjct: 590 IEMRLKVS 597
>XP_005253473
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 111 LEIKLKVSE 119
>XP_005253472
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 111 LEIKLKVSE 119
>XP_005253471
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 141 LEIKLKVSE 149
>XP_005253470
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 141 LEIKLKVSE 149
>XP_006719168
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 141 LEIKLKVSE 149
>XP_006719167
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 141 LEIKLKVSE 149
>XP_006719166
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LELRIKVSK 9
           LE+++KVS+
Sbjct: 149 LEIKLKVSE 157
>XP_006714056
          Length = 221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 175 LELRVKTVK 183
>XP_005248108
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 245 LELRVKTVK 253
>XP_005248109
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 245 LELRVKTVK 253
>XP_006714055
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           LELR+K  K
Sbjct: 245 LELRVKTVK 253
>NP_001248348
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           +ELRIK  K
Sbjct: 224 IELRIKKKK 232
>NP_004624
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           +ELRIK  K
Sbjct: 224 IELRIKKKK 232
>XP_006712799
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           +ELRIK  K
Sbjct: 249 IELRIKKKK 257
>XP_006712798
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           +ELRIK  K
Sbjct: 139 IELRIKKKK 147
>XP_006712797
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LELRIKVSK 9
           +ELRIK  K
Sbjct: 224 IELRIKKKK 232
>XP_006712796
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LELRIKVSK 9
           +ELRIK S+
Sbjct: 249 IELRIKRSR 257
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.139    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,386
Number of extensions: 416
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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