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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1135
XP_005271621                                                           18    1135
XP_006718907                                                           18    1135
XP_006718906                                                           18    1135
XP_005271619                                                           18    1135
XP_005271618                                                           18    1135
NP_671723                                                              16    5631
NP_001268660                                                           16    5631
XP_006719751                                                           16    5631
XP_006719750                                                           16    5631
XP_005269277                                                           16    5631
NP_066997                                                              15    9605
NP_004658                                                              15    9605
NP_067002                                                              15    9605
NP_872630                                                              15    9605
NP_003334                                                              15    9605
NP_001189418                                                           15    9605
NP_714916                                                              15    9605
NP_055640                                                              15    9605
NP_076994                                                              15    9605
NP_061927                                                              15    9605
XP_006720790                                                           15    9605
XP_005268334                                                           15    9605
XP_005268333                                                           15    9605
XP_006720789                                                           15    9605
XP_005254132                                                           15    9605
XP_006717969                                                           15    9605
XP_005269977                                                           15    9605
XP_006717968                                                           15    9605
XP_006717967                                                           15    9605
XP_006717966                                                           15    9605
XP_006717965                                                           15    9605
XP_005245441                                                           15    9605
XP_005245439                                                           15    9605
XP_005245440                                                           15    9605
XP_005245438                                                           15    9605

>NP_000042
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 608 LEKILVSLT 616



>XP_005271621
          Length = 2708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 260 LEKILVSLT 268



>XP_006718907
          Length = 3050

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 608 LEKILVSLT 616



>XP_006718906
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 608 LEKILVSLT 616



>XP_005271619
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 608 LEKILVSLT 616



>XP_005271618
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           LEKIL+SLT
Sbjct: 608 LEKILVSLT 616



>NP_671723
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LEKILLSLT 9
           LEK+ +S+T
Sbjct: 92  LEKVFISIT 100



>NP_001268660
          Length = 334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LEKILLSLT 9
          LEK+ +S+T
Sbjct: 34 LEKVFISIT 42



>XP_006719751
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LEKILLSLT 9
          LEK+ +S+T
Sbjct: 34 LEKVFISIT 42



>XP_006719750
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LEKILLSLT 9
           LEK+ +S+T
Sbjct: 92  LEKVFISIT 100



>XP_005269277
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LEKILLSLT 9
           LEK+ +S+T
Sbjct: 92  LEKVFISIT 100



>NP_066997
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEKILLSL 8
           LE+ILL+L
Sbjct: 725 LERILLTL 732



>NP_004658
          Length = 4834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LEKILLSL 8
            L KILLSL
Sbjct: 3380 LAKILLSL 3387



>NP_067002
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKILLSLT 9
           E +LLSLT
Sbjct: 198 EDVLLSLT 205



>NP_872630
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LEKILLSL 8
          +EKILLS+
Sbjct: 88 VEKILLSV 95



>NP_003334
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEKILLSL 8
           +EKILLS+
Sbjct: 116 VEKILLSV 123



>NP_001189418
          Length = 95

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LEKILLSL 8
          +EKILLS+
Sbjct: 46 VEKILLSV 53



>NP_714916
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKILLSLT 9
           ++ILLSLT
Sbjct: 219 DEILLSLT 226



>NP_055640
          Length = 2271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEKILLSL 8
           LE+ILL+L
Sbjct: 700 LERILLTL 707



>NP_076994
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LEKILLSLT 9
           ++ ILLSLT
Sbjct: 214 MDAILLSLT 222



>NP_061927
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 753 IEKILLNIS 761



>XP_006720790
          Length = 4748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LEKILLSL 8
            L KILLSL
Sbjct: 3294 LAKILLSL 3301



>XP_005268334
          Length = 4796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LEKILLSL 8
            L KILLSL
Sbjct: 3342 LAKILLSL 3349



>XP_005268333
          Length = 4796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LEKILLSL 8
            L KILLSL
Sbjct: 3342 LAKILLSL 3349



>XP_006720789
          Length = 4829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LEKILLSL 8
            L KILLSL
Sbjct: 3375 LAKILLSL 3382



>XP_005254132
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LEKILLSLT 9
           ++ ILLSLT
Sbjct: 214 MDAILLSLT 222



>XP_006717969
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 357 IEKILLNIS 365



>XP_005269977
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 473 IEKILLNIS 481



>XP_006717968
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 870 IEKILLNIS 878



>XP_006717967
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 870 IEKILLNIS 878



>XP_006717966
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 870 IEKILLNIS 878



>XP_006717965
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEKILLSLT 9
           +EKILL+++
Sbjct: 876 IEKILLNIS 884



>XP_005245441
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKILLSLT 9
           E +LLSLT
Sbjct: 198 EDVLLSLT 205



>XP_005245439
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKILLSLT 9
           E +LLSLT
Sbjct: 198 EDVLLSLT 205



>XP_005245440
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKILLSLT 9
           E +LLSLT
Sbjct: 198 EDVLLSLT 205



>XP_005245438
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKILLSLT 9
           E +LLSLT
Sbjct: 198 EDVLLSLT 205



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.142    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 419,126
Number of extensions: 702
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)