Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              19     869
XP_006713721                                                           19     869
NP_001180246                                                           17    4312
NP_001180244                                                           17    4312
NP_001180245                                                           17    4312
NP_071350                                                              17    4312
NP_001180243                                                           17    4312
NP_001136018                                                           17    4312
NP_361013                                                              17    4312
NP_003298                                                              16    5631
NP_055771                                                              16    5631
NP_009224                                                              16    5631
NP_001258862                                                           16    5631
NP_001239133                                                           16    5631
NP_001002029                                                           16    5631
NP_001229752                                                           16    5631
XP_006724113                                                           16    5631
XP_006724112                                                           16    5631
XP_005261228                                                           16    5631
XP_005271517                                                           16    5631
XP_006718857                                                           16    5631
XP_005271516                                                           16    5631
XP_005271515                                                           16    5631
XP_005271514                                                           16    5631
XP_005271513                                                           16    5631
XP_005271512                                                           16    5631
XP_005271511                                                           16    5631
XP_006718856                                                           16    5631
XP_006718855                                                           16    5631
XP_006718854                                                           16    5631
XP_006718853                                                           16    5631
XP_005271510                                                           16    5631
XP_005271509                                                           16    5631
XP_006718852                                                           16    5631
XP_006718851                                                           16    5631
NP_009045                                                              16    7355
NP_001070737                                                           16    7355
NP_003378                                                              16    7355
NP_002806                                                              16    7355
NP_001257411                                                           16    7355
XP_006712790                                                           16    7355
NP_056323                                                              15    9605
NP_001171646                                                           15    9605
NP_056276                                                              15    9605
NP_001171647                                                           15    9605
NP_061758                                                              15    9605
XP_006726196                                                           15    9605
XP_005275679                                                           15    9605
XP_005275678                                                           15    9605
XP_005275677                                                           15    9605
XP_006726007                                                           15    9605
XP_005275375                                                           15    9605
XP_005275374                                                           15    9605
XP_005275373                                                           15    9605
XP_006725811                                                           15    9605
XP_005275118                                                           15    9605
XP_005275117                                                           15    9605
XP_005275116                                                           15    9605
XP_006725592                                                           15    9605
XP_005272963                                                           15    9605
XP_005272962                                                           15    9605
XP_005272961                                                           15    9605
XP_006725113                                                           15    9605
XP_005274953                                                           15    9605
XP_005274952                                                           15    9605
XP_005274951                                                           15    9605
XP_005258298                                                           15    9605
XP_006722500                                                           15    9605
XP_006722499                                                           15    9605
XP_006715283                                                           15    9605
XP_005249486                                                           15    9605
XP_005249485                                                           15    9605
XP_005249484                                                           15    9605
NP_079534                                                              15    9605
>NP_006209
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            LDKTEQ AL
Sbjct: 1028 LDKTEQEAL 1036
>XP_006713721
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            LDKTEQ AL
Sbjct: 1028 LDKTEQEAL 1036
>NP_001180246
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           LD+TE+ AL
Sbjct: 247 LDRTEELAL 255
>NP_001180244
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           LD+TE+ AL
Sbjct: 247 LDRTEELAL 255
>NP_001180245
          Length = 444

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           LD+TE+ AL
Sbjct: 198 LDRTEELAL 206
>NP_071350
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           LD+TE+ AL
Sbjct: 247 LDRTEELAL 255
>NP_001180243
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           LD+TE+ AL
Sbjct: 247 LDRTEELAL 255
>NP_001136018
          Length = 1076

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LDKTEQA 7
           LDKTEQ+
Sbjct: 172 LDKTEQS 178
>NP_361013
          Length = 1076

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LDKTEQA 7
           LDKTEQ+
Sbjct: 172 LDKTEQS 178
>NP_003298
          Length = 1503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            L+K E+AAL
Sbjct: 1113 LEKNEEAAL 1121
>NP_055771
          Length = 1460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 733 EKSEQAAL 740
>NP_009224
          Length = 1744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LDKTEQ 6
            LDKTEQ
Sbjct: 1028 LDKTEQ 1033
>NP_001258862
          Length = 1455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 736 EKSEQAAL 743
>NP_001239133
          Length = 1698

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LDKTEQ 6
            LDKTEQ
Sbjct: 1028 LDKTEQ 1033
>NP_001002029
          Length = 1744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LDKTEQ 6
            LDKTEQ
Sbjct: 1028 LDKTEQ 1033
>NP_001229752
          Length = 1744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LDKTEQ 6
            LDKTEQ
Sbjct: 1028 LDKTEQ 1033
>XP_006724113
          Length = 1206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            L+K E+AAL
Sbjct: 1113 LEKNEEAAL 1121
>XP_006724112
          Length = 1469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            L+K E+AAL
Sbjct: 1113 LEKNEEAAL 1121
>XP_005261228
          Length = 1503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDKTEQAAL 9
            L+K E+AAL
Sbjct: 1113 LEKNEEAAL 1121
>XP_005271517
          Length = 1350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 623 EKSEQAAL 630
>XP_006718857
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 707 EKSEQAAL 714
>XP_005271516
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 710 EKSEQAAL 717
>XP_005271515
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 710 EKSEQAAL 717
>XP_005271514
          Length = 1455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 736 EKSEQAAL 743
>XP_005271513
          Length = 1460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 733 EKSEQAAL 740
>XP_005271512
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 736 EKSEQAAL 743
>XP_005271511
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           +K+EQAAL
Sbjct: 736 EKSEQAAL 743
>XP_006718856
          Length = 1976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1249 EKSEQAAL 1256
>XP_006718855
          Length = 1979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1252 EKSEQAAL 1259
>XP_006718854
          Length = 1999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1272 EKSEQAAL 1279
>XP_006718853
          Length = 2017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1298 EKSEQAAL 1305
>XP_005271510
          Length = 2022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1295 EKSEQAAL 1302
>XP_005271509
          Length = 2024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1298 EKSEQAAL 1305
>XP_006718852
          Length = 2025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1298 EKSEQAAL 1305
>XP_006718851
          Length = 2025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    DKTEQAAL 9
            +K+EQAAL
Sbjct: 1298 EKSEQAAL 1305
>NP_009045
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDKTEQAA 8
           L +TEQAA
Sbjct: 725 LQRTEQAA 732
>NP_001070737
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LDKTEQA 7
          L+KTEQA
Sbjct: 25 LNKTEQA 31
>NP_003378
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LDKTEQA 7
          L+KTEQA
Sbjct: 25 LNKTEQA 31
>NP_002806
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           +DKT +AAL
Sbjct: 393 VDKTYEAAL 401
>NP_001257411
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDKTEQAAL 9
           +DKT +AAL
Sbjct: 393 VDKTYEAAL 401
>XP_006712790
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LDKTEQA 7
          L+KTEQA
Sbjct: 25 LNKTEQA 31
>NP_056323
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           DK+E+A+L
Sbjct: 213 DKSEEASL 220
>NP_001171646
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           DK+E+A+L
Sbjct: 213 DKSEEASL 220
>NP_056276
          Length = 1311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDKTEQA 7
           LDK EQA
Sbjct: 430 LDKPEQA 436
>NP_001171647
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DKTEQAAL 9
           DK+E+A+L
Sbjct: 213 DKSEEASL 220
>NP_061758
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDKTEQAAL 9
           LD+ EQA L
Sbjct: 200 LDREEQAEL 208
>XP_006726196
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275679
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275678
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275677
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_006726007
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275375
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275374
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275373
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_006725811
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275118
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275117
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005275116
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_006725592
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005272963
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005272962
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005272961
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_006725113
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005274953
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005274952
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005274951
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005258298
          Length = 1091

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDKTEQA 7
           LDK EQA
Sbjct: 210 LDKPEQA 216
>XP_006722500
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDKTEQA 7
           LDK EQA
Sbjct: 430 LDKPEQA 436
>XP_006722499
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDKTEQA 7
           LDK EQA
Sbjct: 430 LDKPEQA 436
>XP_006715283
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005249486
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005249485
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>XP_005249484
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
>NP_079534
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKTEQAAL 9
          D TE+AAL
Sbjct: 47 DLTEEAAL 54
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.117    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 431,965
Number of extensions: 692
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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