Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185763                                                           21     229
NP_055459                                                              21     229
XP_006711718                                                           21     229
XP_006711716                                                           21     229
XP_006711715                                                           21     229
XP_006711714                                                           21     229
XP_006711713                                                           21     229
XP_006711712                                                           21     229
XP_006711710                                                           21     229
XP_006711709                                                           21     229
XP_005277503                                                           21     229
XP_005273038                                                           21     229
XP_006711708                                                           21     229
XP_005277500                                                           21     229
XP_006711707                                                           21     229
XP_005277499                                                           21     229
XP_006711706                                                           21     229
XP_006711705                                                           21     229
XP_006710142                                                           21     229
XP_006710141                                                           21     229
NP_003493                                                              18    1935
NP_851393                                                              18    1935
XP_005255667                                                           18    1935
XP_005255666                                                           18    1935
XP_005255665                                                           18    1935
XP_005255664                                                           18    1935
NP_001128625                                                           17    3301
XP_005273523                                                           17    3301
XP_006716387                                                           17    3301
XP_005273522                                                           17    3301
XP_005273521                                                           17    3301
XP_005273520                                                           17    3301
XP_006716386                                                           17    3301
NP_001121903                                                           17    3301
NP_001128626                                                           17    3301
NP_056174                                                              17    3301
NP_001185471                                                           16    5631
NP_001185472                                                           16    5631
NP_060028                                                              16    5631
NP_000558                                                              16    5631
NP_001257903                                                           16    5631
NP_060710                                                              16    5631
NP_001188336                                                           16    5631
NP_872337                                                              16    5631
NP_001273278                                                           16    5631
NP_001026881                                                           16    5631
NP_001122089                                                           16    5631
NP_114128                                                              16    5631
NP_001273540                                                           16    5631
NP_036307                                                              16    5631
NP_208385                                                              16    5631
XP_006721269                                                           16    5631
XP_006721228                                                           16    5631
XP_005256347                                                           16    5631
XP_005256346                                                           16    5631
XP_005256345                                                           16    5631
XP_005252908                                                           16    5631
XP_005267236                                                           16    5631
XP_005267235                                                           16    5631
XP_006715650                                                           16    5631
XP_005267234                                                           16    5631
XP_006714955                                                           16    5631
XP_006711493                                                           16    5631
XP_005245363                                                           16    5631
XP_005245362                                                           16    5631
NP_114432                                                              16    7355
NP_149419                                                              16    7355
NP_057533                                                              15    9605
XP_006726899                                                           15    9605
XP_006724472                                                           15    9605
XP_005261681                                                           15    9605
XP_006724322                                                           15    9605
XP_006710183                                                           15    9605
>NP_001185763
          Length = 2362

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1179 LDLGATFTV 1187
>NP_055459
          Length = 2346

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1179 LDLGATFTV 1187
>XP_006711718
          Length = 1436

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIGATFTV 9
           LD+GATFTV
Sbjct: 186 LDLGATFTV 194
>XP_006711716
          Length = 2411

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1245 LDLGATFTV 1253
>XP_006711715
          Length = 2428

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1179 LDLGATFTV 1187
>XP_006711714
          Length = 2429

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1179 LDLGATFTV 1187
>XP_006711713
          Length = 2432

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1182 LDLGATFTV 1190
>XP_006711712
          Length = 2473

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006711710
          Length = 2494

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1245 LDLGATFTV 1253
>XP_006711709
          Length = 2495

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1245 LDLGATFTV 1253
>XP_005277503
          Length = 2498

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_005273038
          Length = 2509

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006711708
          Length = 2512

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_005277500
          Length = 2525

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006711707
          Length = 2553

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_005277499
          Length = 2561

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006711706
          Length = 2591

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006711705
          Length = 2592

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LDIGATFTV 9
            LD+GATFTV
Sbjct: 1342 LDLGATFTV 1350
>XP_006710142
          Length = 671

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIGATFTV 9
           LD+GATFTV
Sbjct: 131 LDLGATFTV 139
>XP_006710141
          Length = 672

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIGATFTV 9
           LD+GATFTV
Sbjct: 131 LDLGATFTV 139
>NP_003493
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 10 LDLGASFT 17
>NP_851393
          Length = 826

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 10 LDLGASFT 17
>XP_005255667
          Length = 473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 59 LDLGASFT 66
>XP_005255666
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 10 LDLGASFT 17
>XP_005255665
          Length = 875

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 59 LDLGASFT 66
>XP_005255664
          Length = 911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LDIGATFT 8
          LD+GA+FT
Sbjct: 59 LDLGASFT 66
>NP_001128625
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>XP_005273523
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>XP_006716387
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>XP_005273522
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>XP_005273521
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 363 LAIGASFTV 371
>XP_005273520
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 363 LAIGASFTV 371
>XP_006716386
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 363 LAIGASFTV 371
>NP_001121903
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>NP_001128626
          Length = 481

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>NP_056174
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIGATFTV 9
           L IGA+FTV
Sbjct: 353 LAIGASFTV 361
>NP_001185471
          Length = 950

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 495 LDIGKVFT 502
>NP_001185472
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 485 LDIGKVFT 492
>NP_060028
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 468 LDIGKVFT 475
>NP_000558
          Length = 224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DIGATFTV 9
          DIG +FTV
Sbjct: 88 DIGYSFTV 95
>NP_001257903
          Length = 5121

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 468 LDIGKVFT 475
>NP_060710
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 192 LDIGRVFT 199
>NP_001188336
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 593 DCGKTFTV 600
>NP_872337
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 565 DCGKTFTV 572
>NP_001273278
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LDIGATFT 8
          LDIG  FT
Sbjct: 92 LDIGRVFT 99
>NP_001026881
          Length = 290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IGATFTV 9
           IG TFTV
Sbjct: 260 IGGTFTV 266
>NP_001122089
          Length = 769

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 536 LDMNRTFTV 544
>NP_114128
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 562 LDMNRTFTV 570
>NP_001273540
          Length = 796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 563 LDMNRTFTV 571
>NP_036307
          Length = 471

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   IGATFT 8
           IGATFT
Sbjct: 241 IGATFT 246
>NP_208385
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   IGATFT 8
           IGATFT
Sbjct: 241 IGATFT 246
>XP_006721269
          Length = 5138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 485 LDIGKVFT 492
>XP_006721228
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 425 DCGKTFTV 432
>XP_005256347
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 537 DCGKTFTV 544
>XP_005256346
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 537 DCGKTFTV 544
>XP_005256345
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DIGATFTV 9
           D G TFTV
Sbjct: 593 DCGKTFTV 600
>XP_005252908
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   IGATFT 8
           IGATFT
Sbjct: 236 IGATFT 241
>XP_005267236
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 535 LDMNRTFTV 543
>XP_005267235
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 563 LDMNRTFTV 571
>XP_006715650
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 542 LDMNRTFTV 550
>XP_005267234
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDIGATFTV 9
           LD+  TFTV
Sbjct: 562 LDMNRTFTV 570
>XP_006714955
          Length = 198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IGATFTV 9
           IG TFTV
Sbjct: 168 IGGTFTV 174
>XP_006711493
          Length = 673

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LDIGATFT 8
          LDIG  FT
Sbjct: 92 LDIGRVFT 99
>XP_005245363
          Length = 723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 142 LDIGRVFT 149
>XP_005245362
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LDIGATFT 8
           LDIG  FT
Sbjct: 192 LDIGRVFT 199
>NP_114432
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   DIGATFTV 9
           ++G TFT+
Sbjct: 626 ELGVTFTI 633
>NP_149419
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  DIGATFT 8
          D+G TFT
Sbjct: 68 DLGMTFT 74
>NP_057533
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDIGAT 6
          LD+GAT
Sbjct: 49 LDVGAT 54
>XP_006726899
          Length = 197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDIGAT 6
           LD+GAT
Sbjct: 95  LDVGAT 100
>XP_006724472
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDIGAT 6
           LD+GAT
Sbjct: 98  LDVGAT 103
>XP_005261681
          Length = 145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDIGAT 6
          LD+GAT
Sbjct: 49 LDVGAT 54
>XP_006724322
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDIGAT 6
          LD+GAT
Sbjct: 49 LDVGAT 54
>XP_006710183
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDIGAT 6
           LD+GAT
Sbjct: 98  LDVGAT 103
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.146    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,711
Number of extensions: 994
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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