Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1135
NP_000242                                                              18    1135
XP_005264389                                                           18    1135
NP_598328                                                              17    3301
NP_003169                                                              17    3301
NP_001129246                                                           17    3301
NP_443148                                                              17    3301
XP_006721725                                                           17    3301
XP_005257064                                                           17    3301
XP_006721724                                                           17    3301
XP_006721723                                                           17    3301
XP_006713376                                                           17    3301
XP_006713375                                                           17    3301
XP_006713374                                                           17    3301
NP_003481                                                              17    3301
NP_598344                                                              17    3301
NP_055847                                                              17    4312
XP_005266355                                                           17    4312
XP_005266354                                                           17    4312
XP_005266353                                                           17    4312
XP_005266352                                                           17    4312
NP_631938                                                              16    5631
NP_006687                                                              16    5631
NP_001157798                                                           16    5631
XP_005271922                                                           16    5631
XP_005271921                                                           16    5631
XP_005271918                                                           16    5631
XP_006714588                                                           16    5631
XP_005271917                                                           16    5631
XP_005271912                                                           16    5631
XP_005271916                                                           16    5631
XP_005271914                                                           16    5631
XP_006714587                                                           16    5631
XP_005271913                                                           16    5631
NP_071445                                                              16    7355
NP_001129061                                                           16    7355
NP_060156                                                              16    7355
XP_006721306                                                           16    7355
XP_006721305                                                           16    7355
XP_005256141                                                           16    7355
XP_005271016                                                           16    7355
NP_006217                                                              15    9605
NP_001164509                                                           15    9605
NP_001275918                                                           15    9605
NP_001159451                                                           15    9605
NP_004034                                                              15    9605
NP_057425                                                              15    9605
XP_006717953                                                           15    9605
XP_006717952                                                           15    9605
XP_006717951                                                           15    9605
XP_006717950                                                           15    9605
XP_006717949                                                           15    9605
XP_006717948                                                           15    9605
XP_005246701                                                           15    9605
XP_005246700                                                           15    9605
NP_001164510                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIAAVKAL 9
           LDIAAV+AL
Sbjct: 236 LDIAAVRAL 244
>NP_000242
          Length = 934

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIAAVKAL 9
           LDIAAV+AL
Sbjct: 302 LDIAAVRAL 310
>XP_005264389
          Length = 921

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LDIAAVKAL 9
           LDIAAV+AL
Sbjct: 302 LDIAAVRAL 310
>NP_598328
          Length = 582

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 367 LDICAVKAV 375
>NP_003169
          Length = 478

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 367 LDICAVKAV 375
>NP_001129246
          Length = 579

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 345 LDICAVKAV 353
>NP_443148
          Length = 679

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA+VKAL
Sbjct: 622 DIASVKAL 629
>XP_006721725
          Length = 613

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA+VKAL
Sbjct: 556 DIASVKAL 563
>XP_005257064
          Length = 653

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA+VKAL
Sbjct: 622 DIASVKAL 629
>XP_006721724
          Length = 654

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA+VKAL
Sbjct: 623 DIASVKAL 630
>XP_006721723
          Length = 680

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA+VKAL
Sbjct: 623 DIASVKAL 630
>XP_006713376
          Length = 325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 110 LDICAVKAV 118
>XP_006713375
          Length = 421

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 206 LDICAVKAV 214
>XP_006713374
          Length = 511

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 367 LDICAVKAV 375
>NP_003481
          Length = 580

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 346 LDICAVKAV 354
>NP_598344
          Length = 444

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI AVKA+
Sbjct: 346 LDICAVKAV 354
>NP_055847
          Length = 1447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKAL
Sbjct: 484 LDLNAVKAL 492
>XP_005266355
          Length = 1448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKAL
Sbjct: 484 LDLNAVKAL 492
>XP_005266354
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKAL
Sbjct: 484 LDLNAVKAL 492
>XP_005266353
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKAL
Sbjct: 484 LDLNAVKAL 492
>XP_005266352
          Length = 1446

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKAL
Sbjct: 484 LDLNAVKAL 492
>NP_631938
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 434 LDVAAVEA 441
>NP_006687
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>NP_001157798
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 437 LDVAAVEA 444
>XP_005271922
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271921
          Length = 713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271918
          Length = 878

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 434 LDVAAVEA 441
>XP_006714588
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 468 LDVAAVEA 475
>XP_005271917
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271912
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>XP_005271916
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 364 LDVAAVEA 371
>XP_005271914
          Length = 1238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 437 LDVAAVEA 444
>XP_006714587
          Length = 1269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 468 LDVAAVEA 475
>XP_005271913
          Length = 1293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDIAAVKA 8
           LD+AAV+A
Sbjct: 507 LDVAAVEA 514
>NP_071445
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDIAAVKA 8
           LD+A VKA
Sbjct: 185 LDLATVKA 192
>NP_001129061
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA++KAL
Sbjct: 333 DIASLKAL 340
>NP_060156
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA++KAL
Sbjct: 333 DIASLKAL 340
>XP_006721306
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDIAAVKA 8
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>XP_006721305
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDIAAVKA 8
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>XP_005256141
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDIAAVKA 8
           LD+A VKA
Sbjct: 158 LDLATVKA 165
>XP_005271016
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DIAAVKAL 9
           DIA++KAL
Sbjct: 333 DIASLKAL 340
>NP_006217
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LDI+A+K +
Sbjct: 158 LDISAIKEI 166
>NP_001164509
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDIAAVKA 8
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
>NP_001275918
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>NP_001159451
          Length = 1994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 628 LDLFAVKAV 636
>NP_004034
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDIAAVKA 8
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
>NP_057425
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_006717953
          Length = 2008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 628 LDLFAVKAV 636
>XP_006717952
          Length = 2300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_006717951
          Length = 2315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_006717950
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_006717949
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_006717948
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDIAAVKAL 9
           LD+ AVKA+
Sbjct: 936 LDLFAVKAV 944
>XP_005246701
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LDIAAVKAL 9
          LDI+A+K +
Sbjct: 79 LDISAIKEI 87
>XP_005246700
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LDIAAVKAL 9
          LDI+A+K +
Sbjct: 84 LDISAIKEI 92
>NP_001164510
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDIAAVKA 8
          LD+AAV A
Sbjct: 44 LDVAAVAA 51
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.137    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 244,709
Number of extensions: 326
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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