Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              20     390
NP_005087                                                              17    2528
NP_001164634                                                           17    2528
NP_001164633                                                           17    2528
NP_963893                                                              17    2528
NP_060105                                                              17    2528
XP_005262367                                                           17    2528
XP_006724778                                                           17    2528
XP_005262366                                                           17    2528
XP_005274094                                                           17    2528
XP_006718644                                                           17    2528
XP_005274093                                                           17    2528
XP_005274092                                                           17    2528
NP_001123230                                                           17    4312
NP_001074293                                                           17    4312
NP_001263982                                                           17    4312
XP_005264188                                                           17    4312
XP_005264187                                                           17    4312
XP_005264186                                                           17    4312
NP_071752                                                              17    4312
NP_004841                                                              16    5631
NP_001185863                                                           16    5631
NP_258261                                                              16    5631
XP_006715303                                                           16    5631
XP_005246247                                                           16    5631
NP_005643                                                              16    7355
NP_001010938                                                           16    7355
NP_005772                                                              16    7355
NP_060379                                                              16    7355
XP_005256181                                                           16    7355
XP_005256180                                                           16    7355
XP_005256179                                                           16    7355
XP_005256178                                                           16    7355
XP_006713531                                                           16    7355
XP_005269332                                                           16    7355
XP_005269331                                                           16    7355
XP_005269330                                                           16    7355
XP_005269329                                                           16    7355
XP_005269328                                                           16    7355
XP_005269327                                                           16    7355
XP_006713530                                                           16    7355
XP_006713529                                                           16    7355
XP_005269326                                                           16    7355
XP_006713528                                                           16    7355
XP_006713527                                                           16    7355
XP_005269325                                                           16    7355
XP_006713526                                                           16    7355
XP_006713525                                                           16    7355
XP_006713524                                                           16    7355
XP_006713523                                                           16    7355
NP_001171989                                                           15    9605
NP_001171991                                                           15    9605
NP_001171990                                                           15    9605
NP_932766                                                              15    9605
NP_004280                                                              15    9605
NP_001159506                                                           15    9605
NP_940940                                                              15    9605
NP_001159507                                                           15    9605
NP_003449                                                              15    9605
NP_004696                                                              15    9605
XP_006713443                                                           15    9605
NP_940877                                                              15    9605
>NP_003290
          Length = 803

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LDGLNSSQI 9
          LDGLN+SQI
Sbjct: 58 LDGLNASQI 66
>NP_005087
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_001164634
          Length = 495

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_001164633
          Length = 1358

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_963893
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_060105
          Length = 885

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DGLNSSQI 9
           DG+NSS+I
Sbjct: 736 DGMNSSKI 743
>XP_005262367
          Length = 1358

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_006724778
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_005262366
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_005274094
          Length = 713

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DGLNSSQI 9
           DG+NSS+I
Sbjct: 564 DGMNSSKI 571
>XP_006718644
          Length = 862

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DGLNSSQI 9
           DG+NSS+I
Sbjct: 713 DGMNSSKI 720
>XP_005274093
          Length = 862

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DGLNSSQI 9
           DG+NSS+I
Sbjct: 713 DGMNSSKI 720
>XP_005274092
          Length = 885

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DGLNSSQI 9
           DG+NSS+I
Sbjct: 736 DGMNSSKI 743
>NP_001123230
          Length = 512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           +GLNSSQ
Sbjct: 206 EGLNSSQ 212
>NP_001074293
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           L+GLN SQ+
Sbjct: 216 LNGLNFSQV 224
>NP_001263982
          Length = 505

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           L+GLN SQ+
Sbjct: 216 LNGLNFSQV 224
>XP_005264188
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           L+GLN SQ+
Sbjct: 216 LNGLNFSQV 224
>XP_005264187
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           L+GLN SQ+
Sbjct: 113 LNGLNFSQV 121
>XP_005264186
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           L+GLN SQ+
Sbjct: 216 LNGLNFSQV 224
>NP_071752
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           +GLNSSQ
Sbjct: 206 EGLNSSQ 212
>NP_004841
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LDGLNS 6
          LDGLNS
Sbjct: 47 LDGLNS 52
>NP_001185863
          Length = 1492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LDGLNSSQI 9
            LDG+++SQ+
Sbjct: 1306 LDGVDTSQL 1314
>NP_258261
          Length = 1464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LDGLNSSQI 9
            LDG+++SQ+
Sbjct: 1278 LDGVDTSQL 1286
>XP_006715303
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LDGLNSSQI 9
            LDG+++SQ+
Sbjct: 1334 LDGVDTSQL 1342
>XP_005246247
          Length = 1417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LDGLNS 6
          LDGLNS
Sbjct: 47 LDGLNS 52
>NP_005643
          Length = 542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GLNSSQ 8
           GLNSSQ
Sbjct: 418 GLNSSQ 423
>NP_001010938
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 396 GLNGSQI 402
>NP_005772
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 333 GLNGSQI 339
>NP_060379
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  GLNSSQI 9
          GLN SQI
Sbjct: 61 GLNKSQI 67
>XP_005256181
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GLNSSQ 8
           GLNSSQ
Sbjct: 340 GLNSSQ 345
>XP_005256180
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GLNSSQ 8
           GLNSSQ
Sbjct: 418 GLNSSQ 423
>XP_005256179
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GLNSSQ 8
           GLNSSQ
Sbjct: 421 GLNSSQ 426
>XP_005256178
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GLNSSQ 8
           GLNSSQ
Sbjct: 421 GLNSSQ 426
>XP_006713531
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_005269332
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  GLNSSQI 9
          GLN SQI
Sbjct: 19 GLNGSQI 25
>XP_005269331
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 94  GLNGSQI 100
>XP_005269330
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 257 GLNGSQI 263
>XP_005269329
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 365 GLNGSQI 371
>XP_005269328
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 333 GLNGSQI 339
>XP_005269327
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 333 GLNGSQI 339
>XP_006713530
          Length = 1063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 341 GLNGSQI 347
>XP_006713529
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_005269326
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 365 GLNGSQI 371
>XP_006713528
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_006713527
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_005269325
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 396 GLNGSQI 402
>XP_006713526
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_006713525
          Length = 1119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 397 GLNGSQI 403
>XP_006713524
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>XP_006713523
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GLNSSQI 9
           GLN SQI
Sbjct: 411 GLNGSQI 417
>NP_001171989
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  DGLNSSQ 8
          DG+NS Q
Sbjct: 48 DGVNSGQ 54
>NP_001171991
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  DGLNSSQ 8
          DG+NS Q
Sbjct: 16 DGVNSGQ 22
>NP_001171990
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  DGLNSSQ 8
          DG+NS Q
Sbjct: 80 DGVNSGQ 86
>NP_932766
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DGLNSSQ 8
           DG+NS Q
Sbjct: 131 DGVNSGQ 137
>NP_004280
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   DGLNSS 7
           DG+NSS
Sbjct: 293 DGMNSS 298
>NP_001159506
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDGLNS 6
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_940940
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDGLNS 6
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_001159507
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDGLNS 6
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG++SSQ
Sbjct: 688 DGISSSQ 694
>NP_004696
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDGLNS 6
           LDG+NS
Sbjct: 448 LDGINS 453
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DGLNSSQ 8
           DG++SSQ
Sbjct: 732 DGISSSQ 738
>NP_940877
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LDGLNSSQI 9
           LDG ++SQ+
Sbjct: 658 LDGRSNSQV 666
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.130    0.329 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,960
Number of extensions: 647
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package