Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_115829                                                              17    2528
XP_005259388                                                           17    2528
XP_005259387                                                           17    2528
XP_005259386                                                           17    2528
XP_005259385                                                           17    2528
NP_114368                                                              16    5631
NP_002810                                                              16    5631
NP_114367                                                              16    5631
NP_001157262                                                           16    5631
NP_005147                                                              16    5631
NP_001231827                                                           16    5631
NP_001231825                                                           16    5631
NP_001103132                                                           16    5631
NP_065104                                                              16    5631
NP_001157260                                                           16    5631
NP_001231826                                                           16    5631
XP_005259655                                                           16    5631
XP_005259654                                                           16    5631
XP_005254620                                                           16    5631
XP_005252381                                                           16    5631
XP_006717409                                                           16    5631
XP_006717408                                                           16    5631
XP_006717407                                                           16    5631
XP_006717406                                                           16    5631
XP_006715707                                                           16    5631
XP_005249672                                                           16    5631
XP_006715706                                                           16    5631
XP_006715705                                                           16    5631
XP_005249670                                                           16    5631
NP_612454                                                              16    5631
NP_001230913                                                           16    7355
NP_068810                                                              16    7355
NP_001138610                                                           16    7355
NP_001230914                                                           16    7355
NP_919416                                                              16    7355
NP_003372                                                              16    7355
NP_055640                                                              16    7355
NP_067013                                                              16    7355
NP_066022                                                              16    7355
XP_006723369                                                           16    7355
XP_005267192                                                           16    7355
XP_006715625                                                           16    7355
XP_005271143                                                           16    7355
XP_005271142                                                           16    7355
XP_005271141                                                           16    7355
NP_001243398                                                           15    9605
NP_036462                                                              15    9605
NP_001243397                                                           15    9605
NP_619542                                                              15    9605
NP_001186084                                                           15    9605
NP_001186085                                                           15    9605
NP_001186087                                                           15    9605
NP_001186086                                                           15    9605
NP_008998                                                              15    9605
NP_001092882                                                           15    9605
NP_006757                                                              15    9605
NP_001092883                                                           15    9605
XP_005274600                                                           15    9605
XP_005269721                                                           15    9605
XP_005273706                                                           15    9605
>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    DFSKLLSS 9
            DFSKLLSS
Sbjct: 1113 DFSKLLSS 1120
>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    DFSKLLSS 9
            DFSKLLSS
Sbjct: 1132 DFSKLLSS 1139
>NP_115829
          Length = 609

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLLS
Sbjct: 250 DFSKLLS 256
>XP_005259388
          Length = 545

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLLS
Sbjct: 186 DFSKLLS 192
>XP_005259387
          Length = 548

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLLS
Sbjct: 189 DFSKLLS 195
>XP_005259386
          Length = 577

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLLS
Sbjct: 218 DFSKLLS 224
>XP_005259385
          Length = 577

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLLS
Sbjct: 218 DFSKLLS 224
>NP_114368
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 255 IDFSKLTS 262
>NP_002810
          Length = 557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 255 IDFSKLTS 262
>NP_114367
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 255 IDFSKLTS 262
>NP_001157262
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 256 IDFSKLTS 263
>NP_005147
          Length = 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 253 IDFSKLTS 260
>NP_001231827
          Length = 558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 259 IDFSKLTS 266
>NP_001231825
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 158 IDFSKLTS 165
>NP_001103132
          Length = 4284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DFSKLLSS 9
           DF KLLS+
Sbjct: 720 DFQKLLST 727
>NP_065104
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   DFSKLLSS 9
           DFS LLSS
Sbjct: 140 DFSVLLSS 147
>NP_001157260
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 225 IDFSKLTS 232
>NP_001231826
          Length = 547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 225 IDFSKLTS 232
>XP_005259655
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 257 IDFSKLTS 264
>XP_005259654
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 257 IDFSKLTS 264
>XP_005254620
          Length = 281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  DFSKLLSS 9
          DFS LLSS
Sbjct: 59 DFSVLLSS 66
>XP_005252381
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 153 IDFSKLTS 160
>XP_006717409
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 222 IDFSKLTS 229
>XP_006717408
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 225 IDFSKLTS 232
>XP_006717407
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 256 IDFSKLTS 263
>XP_006717406
          Length = 558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFSKL S
Sbjct: 259 IDFSKLTS 266
>XP_006715707
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 279 DFSKLLA 285
>XP_005249672
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 279 DFSKLLA 285
>XP_006715706
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 279 DFSKLLA 285
>XP_006715705
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 297 DFSKLLA 303
>XP_005249670
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 491 DFSKLLA 497
>NP_612454
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           DFSKLL+
Sbjct: 279 DFSKLLA 285
>NP_001230913
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 471 MDFSALLS 478
>NP_068810
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 540 MDFSALLS 547
>NP_001138610
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 537 MDFSALLS 544
>NP_001230914
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 437 MDFSALLS 444
>NP_919416
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  DFSKLL 7
          DFSKLL
Sbjct: 89 DFSKLL 94
>NP_003372
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  DFSKLL 7
          DFSKLL
Sbjct: 89 DFSKLL 94
>NP_055640
          Length = 2271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DFSKLL 7
           DFSKLL
Sbjct: 579 DFSKLL 584
>NP_067013
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LDFSKLLS 8
           +DFSKL++
Sbjct: 252 IDFSKLVN 259
>NP_066022
          Length = 2564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDFSKLLSS 9
           +DFSKL  S
Sbjct: 227 VDFSKLTKS 235
>XP_006723369
          Length = 2394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LDFSKLLSS 9
           +DFSKL  S
Sbjct: 227 VDFSKLTKS 235
>XP_005267192
          Length = 168

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  DFSKLL 7
          DFSKLL
Sbjct: 89 DFSKLL 94
>XP_006715625
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  DFSKLL 7
          DFSKLL
Sbjct: 89 DFSKLL 94
>XP_005271143
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LDFSKLLS 8
           +DFSKL++
Sbjct: 252 IDFSKLVN 259
>XP_005271142
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LDFSKLLS 8
           +DFSKL++
Sbjct: 252 IDFSKLVN 259
>XP_005271141
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LDFSKLLS 8
           +DFSKL++
Sbjct: 252 IDFSKLVN 259
>NP_001243398
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 582 IDFSYLLS 589
>NP_036462
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 874 IDFSYLLS 881
>NP_001243397
          Length = 1890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 691 IDFSYLLS 698
>NP_619542
          Length = 1041

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           +FSKLLS
Sbjct: 362 NFSKLLS 368
>NP_001186084
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 461 IDFSYLLS 468
>NP_001186085
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 352 IDFSYLLS 359
>NP_001186087
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 322 IDFSYLLS 329
>NP_001186086
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 381 IDFSYLLS 388
>NP_008998
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 491 IDFSYLLS 498
>NP_001092882
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 663 IDFSYLLS 670
>NP_006757
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 663 IDFSYLLS 670
>NP_001092883
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 663 IDFSYLLS 670
>XP_005274600
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DFSKLLS 8
           +FSKLLS
Sbjct: 380 NFSKLLS 386
>XP_005269721
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 874 IDFSYLLS 881
>XP_005273706
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDFSKLLS 8
           +DFS LLS
Sbjct: 656 IDFSYLLS 663
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.132    0.321 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,589
Number of extensions: 601
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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