Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           17    3301
NP_000242                                                              17    3301
NP_003356                                                              17    3301
XP_005264389                                                           17    3301
NP_000285                                                              17    4312
NP_001165903                                                           17    4312
XP_005255422                                                           17    4312
XP_006721117                                                           17    4312
XP_005255421                                                           17    4312
XP_005255420                                                           17    4312
NP_001005289                                                           17    4312
NP_001127951                                                           16    5631
NP_439896                                                              16    5631
NP_060573                                                              16    5631
XP_006726572                                                           16    5631
XP_006726571                                                           16    5631
XP_006726570                                                           16    5631
XP_003960511                                                           16    5631
XP_006717414                                                           16    5631
XP_006715391                                                           16    5631
XP_005271048                                                           16    5631
XP_006710283                                                           16    5631
XP_006710282                                                           16    5631
NP_001095896                                                           15    9605
NP_001188309                                                           15    9605
NP_001020949                                                           15    9605
NP_057524                                                              15    9605
NP_006545                                                              15    9605
NP_002486                                                              15    9605
NP_689982                                                              15    9605
NP_079334                                                              15    9605
NP_001243529                                                           15    9605
NP_660150                                                              15    9605
NP_001269307                                                           15    9605
NP_036505                                                              15    9605
NP_001243528                                                           15    9605
NP_001243530                                                           15    9605
XP_006726548                                                           15    9605
XP_006726547                                                           15    9605
XP_006726546                                                           15    9605
XP_006726545                                                           15    9605
XP_006726544                                                           15    9605
XP_006726543                                                           15    9605
XP_006726542                                                           15    9605
XP_006726541                                                           15    9605
XP_006726540                                                           15    9605
XP_006726539                                                           15    9605
XP_006726538                                                           15    9605
XP_006726537                                                           15    9605
XP_005259031                                                           15    9605
XP_006723301                                                           15    9605
XP_005259029                                                           15    9605
XP_006723300                                                           15    9605
XP_005259028                                                           15    9605
XP_006722778                                                           15    9605
XP_005259585                                                           15    9605
XP_006722777                                                           15    9605
XP_006716926                                                           15    9605
XP_006716925                                                           15    9605
XP_006716924                                                           15    9605
XP_006716923                                                           15    9605
XP_006716922                                                           15    9605
XP_006716921                                                           15    9605
XP_006716920                                                           15    9605
XP_006716919                                                           15    9605
XP_006716918                                                           15    9605
XP_006716917                                                           15    9605
XP_006716916                                                           15    9605
XP_005263921                                                           15    9605
XP_005263920                                                           15    9605
XP_005263919                                                           15    9605
XP_006712262                                                           15    9605
NP_005990                                                              15    9605
NP_001177945                                                           15    9605
>NP_001245210
          Length = 868

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1   LDAV-SFAHV 9
           LDAV SFAHV
Sbjct: 536 LDAVVSFAHV 545
>NP_000242
          Length = 934

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1   LDAV-SFAHV 9
           LDAV SFAHV
Sbjct: 602 LDAVVSFAHV 611
>NP_003356
          Length = 480

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DAVSFAHV 9
           DA+ FAHV
Sbjct: 280 DALPFAHV 287
>XP_005264389
          Length = 921

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1   LDAV-SFAHV 9
           LDAV SFAHV
Sbjct: 602 LDAVVSFAHV 611
>NP_000285
          Length = 406

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L+AVSF H
Sbjct: 138 LEAVSFLH 145
>NP_001165903
          Length = 374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L+AVSF H
Sbjct: 138 LEAVSFLH 145
>XP_005255422
          Length = 301

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDAVSFAH 8
          L+AVSF H
Sbjct: 29 LEAVSFLH 36
>XP_006721117
          Length = 301

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDAVSFAH 8
          L+AVSF H
Sbjct: 29 LEAVSFLH 36
>XP_005255421
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LDAVSFAH 8
          L+AVSF H
Sbjct: 36 LEAVSFLH 43
>XP_005255420
          Length = 410

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L+AVSF H
Sbjct: 138 LEAVSFLH 145
>NP_001005289
          Length = 320

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LDAVSFAHV 9
           L AVS+AH+
Sbjct: 221 LIAVSYAHI 229
>NP_001127951
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LDAVSFAHV 9
           ++A+SF HV
Sbjct: 330 VNAISFEHV 338
>NP_439896
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LDAVSFA 7
           +DAVSFA
Sbjct: 139 MDAVSFA 145
>NP_060573
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LDAVSFAHV 9
           ++A+SF HV
Sbjct: 330 VNAISFEHV 338
>XP_006726572
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 1209 AVSFVHV 1215
>XP_006726571
          Length = 3681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 2865 AVSFVHV 2871
>XP_006726570
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 2865 AVSFVHV 2871
>XP_003960511
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 2865 AVSFVHV 2871
>XP_006717414
          Length = 5100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 4243 AVSFVHV 4249
>XP_006715391
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LDAVSFA 7
           +DAVSFA
Sbjct: 139 MDAVSFA 145
>XP_005271048
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LDAVSFAHV 9
           ++A+SF HV
Sbjct: 330 VNAISFEHV 338
>XP_006710283
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 1209 AVSFVHV 1215
>XP_006710282
          Length = 2621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    AVSFAHV 9
            AVSF HV
Sbjct: 1764 AVSFVHV 1770
>NP_001095896
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           +DA  FAH+
Sbjct: 856 IDARQFAHL 864
>NP_001188309
          Length = 1288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>NP_001020949
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 241 LDALEFLH 248
>NP_057524
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 291 LDALEFLH 298
>NP_006545
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           LDA+ F H+
Sbjct: 211 LDALVFGHL 219
>NP_002486
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DAVSFA 7
           DAVSFA
Sbjct: 133 DAVSFA 138
>NP_689982
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAVSFAH 8
           DAV+F H
Sbjct: 365 DAVAFPH 371
>NP_079334
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDAVSF 6
           LDAVSF
Sbjct: 705 LDAVSF 710
>NP_001243529
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDAVSF 6
           LDAVSF
Sbjct: 663 LDAVSF 668
>NP_660150
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 302 LSAVSFAY 309
>NP_001269307
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDAVSF 6
           LDAVSF
Sbjct: 579 LDAVSF 584
>NP_036505
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AVSFAHV 9
           +VS+AHV
Sbjct: 224 SVSYAHV 230
>NP_001243528
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDAVSF 6
           LDAVSF
Sbjct: 682 LDAVSF 687
>NP_001243530
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDAVSF 6
           LDAVSF
Sbjct: 692 LDAVSF 697
>XP_006726548
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006726547
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 558 LSAVSFAY 565
>XP_006726546
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006726545
          Length = 1157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006726544
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 519 LSAVSFAY 526
>XP_006726543
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 559 LSAVSFAY 566
>XP_006726542
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006726541
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 618 LSAVSFAY 625
>XP_006726540
          Length = 1287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 651 LSAVSFAY 658
>XP_006726539
          Length = 1288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006726538
          Length = 1297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 651 LSAVSFAY 658
>XP_006726537
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_005259031
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 291 LDALEFLH 298
>XP_006723301
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 241 LDALEFLH 248
>XP_005259029
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 241 LDALEFLH 248
>XP_006723300
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 291 LDALEFLH 298
>XP_005259028
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LDAVSFAH 8
           LDA+ F H
Sbjct: 291 LDALEFLH 298
>XP_006722778
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAVSFAH 8
           DAV+F H
Sbjct: 411 DAVAFPH 417
>XP_005259585
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAVSFAH 8
           DAV+F H
Sbjct: 365 DAVAFPH 371
>XP_006722777
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAVSFAH 8
           DAV+F H
Sbjct: 411 DAVAFPH 417
>XP_006716926
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006716925
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006716924
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006716923
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006716922
          Length = 1157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_006716921
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 518 LSAVSFAY 525
>XP_006716920
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 558 LSAVSFAY 565
>XP_006716919
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 618 LSAVSFAY 625
>XP_006716918
          Length = 1287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 651 LSAVSFAY 658
>XP_006716917
          Length = 1297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 651 LSAVSFAY 658
>XP_006716916
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           L AVSFA+
Sbjct: 652 LSAVSFAY 659
>XP_005263921
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           +DA  FAH+
Sbjct: 863 IDARQFAHL 871
>XP_005263920
          Length = 1155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           +DA  FAH+
Sbjct: 871 IDARQFAHL 879
>XP_005263919
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           +DA  FAH+
Sbjct: 878 IDARQFAHL 886
>XP_006712262
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LDAVSFAHV 9
           LDA+ F H+
Sbjct: 101 LDALVFGHL 109
>NP_005990
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDAVSFAH 8
           ++AVSF H
Sbjct: 128 VEAVSFQH 135
>NP_001177945
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DAVSFAHV 9
           DAV+ AHV
Sbjct: 253 DAVTKAHV 260
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,218
Number of extensions: 760
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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