Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000273                                                              17    4312
NP_001171475                                                           17    4312
NP_001035829                                                           17    4312
NP_001166996                                                           17    4312
NP_004591                                                              17    4312
NP_001166995                                                           17    4312
NP_001244960                                                           17    4312
NP_001035828                                                           17    4312
XP_006721650                                                           17    4312
XP_005254116                                                           17    4312
XP_006711560                                                           17    4312
XP_006711559                                                           17    4312
XP_006711558                                                           17    4312
NP_003546                                                              17    4312
NP_848652                                                              16    5631
XP_006710219                                                           16    5631
NP_001004476                                                           16    5631
NP_065759                                                              16    7355
NP_001128243                                                           16    7355
NP_001243183                                                           16    7355
NP_001243181                                                           16    7355
NP_001965                                                              16    7355
NP_001243184                                                           16    7355
NP_444253                                                              15    9605
NP_067047                                                              15    9605
NP_444255                                                              15    9605
NP_005148                                                              15    9605
NP_055756                                                              15    9605
NP_009297                                                              15    9605
NP_065076                                                              15    9605
NP_002215                                                              15    9605
NP_060587                                                              15    9605
NP_997724                                                              15    9605
NP_006589                                                              15    9605
NP_001264214                                                           15    9605
NP_055445                                                              15    9605
XP_006725069                                                           15    9605
XP_005262187                                                           15    9605
XP_005261449                                                           15    9605
XP_005261448                                                           15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_005255053                                                           15    9605
XP_006718858                                                           15    9605
XP_005270021                                                           15    9605
XP_005270020                                                           15    9605
XP_005270019                                                           15    9605
XP_006717280                                                           15    9605
XP_006717279                                                           15    9605
XP_006717278                                                           15    9605
XP_006717277                                                           15    9605
XP_006717276                                                           15    9605
XP_006717275                                                           15    9605
XP_006717274                                                           15    9605
XP_006717273                                                           15    9605
XP_006717272                                                           15    9605
XP_006715155                                                           15    9605
XP_006715154                                                           15    9605
XP_005248288                                                           15    9605
XP_005247550                                                           15    9605
XP_006713712                                                           15    9605
XP_005247549                                                           15    9605
NP_001139669                                                           15    9605
NP_795370                                                              15    9605
NP_064629                                                              15    9605
>NP_000273
          Length = 728

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  CLIVSRTL 9
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>NP_001171475
          Length = 681

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  CLIVSRTL 9
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>NP_001035829
          Length = 534

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>NP_001166996
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>NP_004591
          Length = 538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>NP_001166995
          Length = 538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>NP_001244960
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  CLIVSRTL 9
          CL++SRT+
Sbjct: 76 CLLLSRTV 83
>NP_001035828
          Length = 525

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>XP_006721650
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCLI+S T
Sbjct: 212 LCLIISYT 219
>XP_005254116
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  CLIVSRTL 9
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>XP_006711560
          Length = 538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 399 MCMVVTRT 406
>XP_006711559
          Length = 560

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 421 MCMVVTRT 428
>XP_006711558
          Length = 560

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LCLIVSRT 8
           +C++V+RT
Sbjct: 421 MCMVVTRT 428
>NP_003546
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCLI+S T
Sbjct: 212 LCLIISYT 219
>NP_848652
          Length = 302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC  VSR+L
Sbjct: 127 LCFAVSRSL 135
>XP_006710219
          Length = 218

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LCLIVSRTL 9
          LC  VSR+L
Sbjct: 43 LCFAVSRSL 51
>NP_001004476
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC IV RT+
Sbjct: 301 LCKIVRRTI 309
>NP_065759
          Length = 1116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LCLIVSRTL 9
           +CL+ +RTL
Sbjct: 286 ICLLGNRTL 294
>NP_001128243
          Length = 1139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LCLIVSRTL 9
           +CL+ +RTL
Sbjct: 309 ICLLGNRTL 317
>NP_001243183
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LCLIVSRTL 9
           +CL++++TL
Sbjct: 502 VCLLLAKTL 510
>NP_001243181
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LCLIVSRTL 9
           +CL++++TL
Sbjct: 591 VCLLLAKTL 599
>NP_001965
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LCLIVSRTL 9
           +CL++++TL
Sbjct: 643 VCLLLAKTL 651
>NP_001243184
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LCLIVSRTL 9
           +CL++++TL
Sbjct: 466 VCLLLAKTL 474
>NP_444253
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCL+ +RT
Sbjct: 472 LCLLKART 479
>NP_067047
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>NP_444255
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCL+ +RT
Sbjct: 472 LCLLKART 479
>NP_005148
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LCLIVSR 7
            LCL +SR
Sbjct: 1039 LCLAISR 1045
>NP_055756
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CLIVSRT 8
          CL +SRT
Sbjct: 65 CLFLSRT 71
>NP_009297
          Length = 1149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    LCLIVSR 7
            LCL +SR
Sbjct: 1058 LCLAISR 1064
>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC+ +SR L
Sbjct: 611 LCVYISREL 619
>NP_002215
          Length = 2671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LCLIVSRTL 9
            LC+ V RTL
Sbjct: 1661 LCIKVLRTL 1669
>NP_060587
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CLIVSR 7
           CL+VSR
Sbjct: 913 CLLVSR 918
>NP_997724
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC+ + RTL
Sbjct: 241 LCITIWRTL 249
>NP_006589
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LCLIVSRTL 9
           +CL+ +RTL
Sbjct: 307 VCLLGNRTL 315
>NP_001264214
          Length = 1437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLIVSRT 8
           CLI +RT
Sbjct: 620 CLIANRT 626
>NP_055445
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC + S+TL
Sbjct: 616 LCTLCSKTL 624
>XP_006725069
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LCLIVSRTL 9
           +CL+ +RTL
Sbjct: 307 VCLLGNRTL 315
>XP_005262187
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LCLIVSRTL 9
          LC+ + RTL
Sbjct: 37 LCITIWRTL 45
>XP_005261449
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLIVSRT 8
           CL +SRT
Sbjct: 127 CLFLSRT 133
>XP_005261448
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLIVSRT 8
           CL +SRT
Sbjct: 127 CLFLSRT 133
>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC+ +SR L
Sbjct: 611 LCVYISREL 619
>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC+ +SR L
Sbjct: 611 LCVYISREL 619
>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC+ +SR L
Sbjct: 611 LCVYISREL 619
>XP_005255053
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LC + S+TL
Sbjct: 616 LCTLCSKTL 624
>XP_006718858
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLIVSRT 8
           CLI +RT
Sbjct: 96  CLIANRT 102
>XP_005270021
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CLIVSR 7
           CL+VSR
Sbjct: 442 CLLVSR 447
>XP_005270020
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CLIVSR 7
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_005270019
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CLIVSR 7
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_006717280
          Length = 2221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717279
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717278
          Length = 2566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717277
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717276
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717275
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717274
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717273
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717272
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    CLIVSRTL 9
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006715155
          Length = 1850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LCLIVSRTL 9
            LC+ V RTL
Sbjct: 1690 LCIKVLRTL 1698
>XP_006715154
          Length = 2700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LCLIVSRTL 9
            LC+ V RTL
Sbjct: 1690 LCIKVLRTL 1698
>XP_005248288
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LCLIVSRTL 9
           +CL+ +RTL
Sbjct: 307 VCLLGNRTL 315
>XP_005247550
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCL+ +RT
Sbjct: 482 LCLLKART 489
>XP_006713712
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCL+ +RT
Sbjct: 482 LCLLKART 489
>XP_005247549
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LCLIVSRT 8
           LCL+ +RT
Sbjct: 482 LCLLKART 489
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    CLIVSRT 8
            C+++SRT
Sbjct: 5546 CVVLSRT 5552
>NP_795370
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LCLIVS 6
           LCLI+S
Sbjct: 243 LCLIIS 248
>NP_064629
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LCLIVSRTL 9
           LCL +SR L
Sbjct: 369 LCLQISRHL 377
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.150    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 424,051
Number of extensions: 575
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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