Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1482
NP_001075109                                                           18    1482
NP_004955                                                              15    9605
NP_004963                                                              15    9605
NP_001518                                                              15    9605
NP_037518                                                              15    9605
NP_998816                                                              15    9605
XP_005268803                                                           15    9605
XP_005268802                                                           15    9605
XP_005268801                                                           15    9605
XP_005268800                                                           15    9605
XP_005268799                                                           15    9605
XP_005251512                                                           15    9605
NP_056090                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LAVLELMRS 9
            LAVLELM+S
Sbjct: 1577 LAVLELMQS 1585
>NP_001075109
          Length = 4097

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LAVLELMRS 9
            LAVLELM+S
Sbjct: 1577 LAVLELMQS 1585
>NP_004955
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAVLELMR 8
           LA+LEL++
Sbjct: 158 LAILELLK 165
>NP_004963
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAVLELMR 8
           +AVL++MR
Sbjct: 181 MAVLDMMR 188
>NP_001518
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAVLELMR 8
           LA+LEL++
Sbjct: 159 LAILELLK 166
>NP_037518
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           LAV EL++S
Sbjct: 362 LAVYELLKS 370
>NP_998816
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           LAV EL++S
Sbjct: 343 LAVYELLKS 351
>XP_005268803
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 780 LDVLEIMRN 788
>XP_005268802
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 781 LDVLEIMRN 789
>XP_005268801
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 592 LDVLEIMRN 600
>XP_005268800
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 593 LDVLEIMRN 601
>XP_005268799
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 781 LDVLEIMRN 789
>XP_005251512
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAVLELMR 8
           +AVL++MR
Sbjct: 181 MAVLDMMR 188
>NP_056090
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAVLELMRS 9
           L VLE+MR+
Sbjct: 780 LDVLEIMRN 788
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.139    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 316,220
Number of extensions: 421
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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