Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              17    3301
XP_005273257                                                           17    3301
NP_065796                                                              16    5631
XP_005249302                                                           16    5631
NP_001093250                                                           16    7355
NP_115486                                                              16    7355
NP_001007562                                                           16    7355
NP_997254                                                              16    7355
XP_005258573                                                           16    7355
XP_005258572                                                           16    7355
XP_005252508                                                           16    7355
XP_006717511                                                           16    7355
XP_005252507                                                           16    7355
NP_001444                                                              15    9605
NP_001028198                                                           15    9605
NP_112175                                                              15    9605
NP_001171532                                                           15    9605
NP_001171533                                                           15    9605
NP_116161                                                              15    9605
NP_001264                                                              15    9605
NP_001271159                                                           15    9605
NP_149132                                                              15    9605
NP_000529                                                              15    9605
XP_005259736                                                           15    9605
XP_005259735                                                           15    9605
XP_005259734                                                           15    9605
XP_005259733                                                           15    9605
XP_005259732                                                           15    9605
XP_005267740                                                           15    9605
XP_006719025                                                           15    9605
XP_005253725                                                           15    9605
XP_006719024                                                           15    9605
XP_006719023                                                           15    9605
XP_006719022                                                           15    9605
XP_006719021                                                           15    9605
XP_005244894                                                           15    9605
XP_005244893                                                           15    9605
XP_005244892                                                           15    9605
XP_005244890                                                           15    9605
XP_006711187                                                           15    9605
XP_006711186                                                           15    9605
XP_006711185                                                           15    9605
XP_006711184                                                           15    9605
XP_006711183                                                           15    9605
>NP_064450
          Length = 1722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LASVAAAAK 9
           LASVAA AK
Sbjct: 459 LASVAAPAK 467
>XP_005273257
          Length = 1726

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LASVAAAAK 9
           LASVAA AK
Sbjct: 459 LASVAAPAK 467
>NP_065796
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  ASVAAAAK 9
          ASVAAAA+
Sbjct: 3  ASVAAAAR 10
>XP_005249302
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  ASVAAAAK 9
          ASVAAAA+
Sbjct: 3  ASVAAAAR 10
>NP_001093250
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LASVAAAAK 9
           L SVA+AAK
Sbjct: 122 LPSVASAAK 130
>NP_115486
          Length = 542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  LASVAAAA 8
          +ASVAAAA
Sbjct: 29 VASVAAAA 36
>NP_001007562
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LASVAAAA 8
           LAS+AAAA
Sbjct: 487 LASLAAAA 494
>NP_997254
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASVAAAAK 9
           LAS AAA K
Sbjct: 487 LASAAAATK 495
>XP_005258573
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LASVAAAA 8
           LAS+AAAA
Sbjct: 487 LASLAAAA 494
>XP_005258572
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LASVAAAA 8
           LAS+AAAA
Sbjct: 487 LASLAAAA 494
>XP_005252508
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASVAAAAK 9
           LAS AAA K
Sbjct: 487 LASAAAATK 495
>XP_006717511
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASVAAAAK 9
           LAS AAA K
Sbjct: 487 LASAAAATK 495
>XP_005252507
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASVAAAAK 9
           LAS AAA K
Sbjct: 487 LASAAAATK 495
>NP_001444
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LASVAAAA 8
           LAS AAAA
Sbjct: 485 LASAAAAA 492
>NP_001028198
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 528 ASVAAAA 534
>NP_112175
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 607 LASVAAA 613
>NP_001171532
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 639 LASVAAA 645
>NP_001171533
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 599 LASVAAA 605
>NP_116161
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LASVAAAA 8
           LAS AAAA
Sbjct: 561 LASAAAAA 568
>NP_001264
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 224 ASVAAAA 230
>NP_001271159
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LASVAAAA 8
          LAS AAAA
Sbjct: 11 LASAAAAA 18
>NP_149132
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LASVAAAA 8
          LAS AAAA
Sbjct: 11 LASAAAAA 18
>NP_000529
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  ASVAAAA 8
          ASVAAAA
Sbjct: 35 ASVAAAA 41
>XP_005259736
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 348 ASVAAAA 354
>XP_005259735
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 534 ASVAAAA 540
>XP_005259734
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 552 ASVAAAA 558
>XP_005259733
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 563 ASVAAAA 569
>XP_005259732
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 569 ASVAAAA 575
>XP_005267740
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LASVAAAA 8
          LAS AAAA
Sbjct: 11 LASAAAAA 18
>XP_006719025
          Length = 1902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 224 ASVAAAA 230
>XP_005253725
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 217 ASVAAAA 223
>XP_006719024
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 217 ASVAAAA 223
>XP_006719023
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 224 ASVAAAA 230
>XP_006719022
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 224 ASVAAAA 230
>XP_006719021
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ASVAAAA 8
           ASVAAAA
Sbjct: 224 ASVAAAA 230
>XP_005244894
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 374 LASVAAA 380
>XP_005244893
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 607 LASVAAA 613
>XP_005244892
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 639 LASVAAA 645
>XP_005244890
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 639 LASVAAA 645
>XP_006711187
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 689 LASVAAA 695
>XP_006711186
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 693 LASVAAA 699
>XP_006711185
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 699 LASVAAA 705
>XP_006711184
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 701 LASVAAA 707
>XP_006711183
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LASVAAA 7
           LASVAAA
Sbjct: 733 LASVAAA 739
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.103    0.217 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 210,088
Number of extensions: 242
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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