Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_055904                                                              17    3301
XP_006715095                                                           17    3301
XP_006715094                                                           17    3301
XP_006715093                                                           17    3301
XP_006715092                                                           17    3301
NP_277052                                                              17    4312
NP_078969                                                              16    5631
NP_001175                                                              16    5631
NP_079521                                                              16    5631
NP_001275740                                                           16    5631
XP_006722975                                                           16    5631
XP_006722974                                                           16    5631
XP_006722973                                                           16    5631
NP_060787                                                              16    7355
XP_006726462                                                           16    7355
XP_005276267                                                           16    7355
XP_006725507                                                           16    7355
XP_006724975                                                           16    7355
XP_006724973                                                           16    7355
XP_006714030                                                           16    7355
XP_003960032                                                           16    7355
XP_006710288                                                           16    7355
XP_003960929                                                           16    7355
XP_006710203                                                           16    7355
NP_001278086                                                           15    9605
NP_001181876                                                           15    9605
NP_937887                                                              15    9605
NP_937884                                                              15    9605
NP_004944                                                              15    9605
NP_001181875                                                           15    9605
NP_937885                                                              15    9605
NP_886553                                                              15    9605
NP_859422                                                              15    9605
NP_001154992                                                           15    9605
NP_006339                                                              15    9605
NP_061027                                                              15    9605
NP_001137429                                                           15    9605
NP_110411                                                              15    9605
NP_001257822                                                           15    9605
NP_001257821                                                           15    9605
XP_006715633                                                           15    9605
XP_006715632                                                           15    9605
XP_005265088                                                           15    9605
XP_005246128                                                           15    9605
NP_001476                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LASLQRPVG 9
            LASLQ+PVG
Sbjct: 2881 LASLQQPVG 2889
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LASLQRPVG 9
            LASLQ+PVG
Sbjct: 2881 LASLQQPVG 2889
>NP_055904
          Length = 2517

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LASLQRPVG 9
            LASLQ P G
Sbjct: 1986 LASLQLPAG 1994
>XP_006715095
          Length = 2046

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LASLQRPVG 9
            LASLQ P G
Sbjct: 1515 LASLQLPAG 1523
>XP_006715094
          Length = 2407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LASLQRPVG 9
            LASLQ P G
Sbjct: 1876 LASLQLPAG 1884
>XP_006715093
          Length = 2459

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LASLQRPVG 9
            LASLQ P G
Sbjct: 1928 LASLQLPAG 1936
>XP_006715092
          Length = 2490

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LASLQRPVG 9
            LASLQ P G
Sbjct: 1959 LASLQLPAG 1967
>NP_277052
          Length = 1731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SLQRPVG 9
            SLQRP G
Sbjct: 1202 SLQRPAG 1208
>NP_078969
          Length = 303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LASLQRPV 8
           +ASL RPV
Sbjct: 240 IASLSRPV 247
>NP_001175
          Length = 2644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LASLQRP 7
            LASLQ+P
Sbjct: 2303 LASLQKP 2309
>NP_079521
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASLQRPVG 9
           LASLQ P G
Sbjct: 329 LASLQPPPG 337
>NP_001275740
          Length = 141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LASLQRPV 8
           L SLQRP+
Sbjct: 101 LGSLQRPL 108
>XP_006722975
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASLQRPVG 9
           LASLQ P G
Sbjct: 164 LASLQPPPG 172
>XP_006722974
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASLQRPVG 9
           LASLQ P G
Sbjct: 243 LASLQPPPG 251
>XP_006722973
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LASLQRPVG 9
           LASLQ P G
Sbjct: 281 LASLQPPPG 289
>NP_060787
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  ASLQRP 7
          ASLQRP
Sbjct: 34 ASLQRP 39
>XP_006726462
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 74 ALLQRPAG 81
>XP_005276267
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 46 ALLQRPAG 53
>XP_006725507
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 46 ALLQRPAG 53
>XP_006724975
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 45 ALLQRPAG 52
>XP_006724973
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 45 ALLQRPAG 52
>XP_006714030
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 ASLQRP 7
         ASLQRP
Sbjct: 3 ASLQRP 8
>XP_003960032
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 46 ALLQRPAG 53
>XP_006710288
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 42 ALLQRPAG 49
>XP_003960929
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 46 ALLQRPAG 53
>XP_006710203
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ASLQRPVG 9
          A LQRP G
Sbjct: 74 ALLQRPAG 81
>NP_001278086
          Length = 1559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 585 ASMQKPEG 592
>NP_001181876
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 632 ASMQKPEG 639
>NP_937887
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 538 ASMQKPEG 545
>NP_937884
          Length = 1599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 625 ASMQKPEG 632
>NP_004944
          Length = 1404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 429 ASMQKPEG 436
>NP_001181875
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 632 ASMQKPEG 639
>NP_937885
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 461 ASMQKPEG 468
>NP_886553
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           AS+Q+P G
Sbjct: 625 ASMQKPEG 632
>NP_859422
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           ASL RP+G
Sbjct: 687 ASLIRPLG 694
>NP_001154992
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           ASL RP+G
Sbjct: 708 ASLIRPLG 715
>NP_006339
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASLQRPVG 9
           ASL RP+G
Sbjct: 708 ASLIRPLG 715
>NP_061027
          Length = 4599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    SLQRPVG 9
            +LQRP G
Sbjct: 4069 NLQRPTG 4075
>NP_001137429
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LASLQRP 7
           L SLQRP
Sbjct: 293 LMSLQRP 299
>NP_110411
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LASLQRP 7
           L SLQRP
Sbjct: 293 LMSLQRP 299
>NP_001257822
          Length = 113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LQRPVG 9
          +QRPVG
Sbjct: 47 VQRPVG 52
>NP_001257821
          Length = 127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LQRPVG 9
          +QRPVG
Sbjct: 61 VQRPVG 66
>XP_006715633
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LASLQRP 7
           L SLQRP
Sbjct: 293 LMSLQRP 299
>XP_006715632
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LASLQRP 7
           L SLQRP
Sbjct: 293 LMSLQRP 299
>XP_005265088
          Length = 1694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  LASLQRPVG 9
          L SLQ P G
Sbjct: 17 LGSLQLPAG 25
>XP_005246128
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LASLQRPVG 9
          L  +QRP+G
Sbjct: 9  LMMMQRPLG 17
>NP_001476
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LASLQRPVG 9
          L  +QRP+G
Sbjct: 9  LMMMQRPLG 17
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.137    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 654,407
Number of extensions: 895
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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