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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718908                                                           20     509
XP_005271621                                                           20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_065433                                                              16    5631
NP_065717                                                              16    5631
NP_872434                                                              16    5631
XP_005266006                                                           16    5631
XP_005266005                                                           16    5631
XP_006714959                                                           16    5631
XP_006714958                                                           16    5631
XP_005266004                                                           16    5631
XP_006713686                                                           16    5631
XP_006713685                                                           16    5631
XP_006713684                                                           16    5631
XP_006713683                                                           16    5631
XP_006713682                                                           16    5631
XP_006713681                                                           16    5631
XP_006713680                                                           16    5631
XP_005247488                                                           16    5631
NP_004975                                                              16    7355
NP_004513                                                              16    7355
NP_004512                                                              16    7355
NP_005600                                                              15    9605
NP_002854                                                              15    9605
NP_001017975                                                           15    9605
NP_002853                                                              15    9605
XP_006723664                                                           15    9605
XP_005275805                                                           15    9605

>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 2261 LARTFKNTQ 2269



>XP_006718908
          Length = 1708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           LART KNTQ
Sbjct: 913 LARTFKNTQ 921



>XP_005271621
          Length = 2708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 1913 LARTFKNTQ 1921



>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 2255 LARTFKNTQ 2263



>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 2261 LARTFKNTQ 2269



>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 2261 LARTFKNTQ 2269



>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LARTLKNTQ 9
            LART KNTQ
Sbjct: 2261 LARTFKNTQ 2269



>NP_065433
          Length = 1091

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           LAR+LKN +
Sbjct: 869 LARSLKNEE 877



>NP_065717
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 312 RTLKNT 317



>NP_872434
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 418 LSHTLKHTQ 426



>XP_005266006
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 132 RTLKNT 137



>XP_005266005
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 132 RTLKNT 137



>XP_006714959
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 276 RTLKNT 281



>XP_006714958
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 276 RTLKNT 281



>XP_005266004
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTLKNT 8
           RTLKNT
Sbjct: 315 RTLKNT 320



>XP_006713686
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 418 LSHTLKHTQ 426



>XP_006713685
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_006713684
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_006713683
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_006713682
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_006713681
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_006713680
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>XP_005247488
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LARTLKNTQ 9
           L+ TLK+TQ
Sbjct: 419 LSHTLKHTQ 427



>NP_004975
          Length = 1032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARTLKNT 8
           A+T+KNT
Sbjct: 324 AKTIKNT 330



>NP_004513
          Length = 957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARTLKNT 8
           A+T+KNT
Sbjct: 324 AKTIKNT 330



>NP_004512
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARTLKNT 8
           A+T+KNT
Sbjct: 322 AKTIKNT 328



>NP_005600
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LARTLKNT 8
          + RTL+NT
Sbjct: 92 MGRTLQNT 99



>NP_002854
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LARTLKNT 8
          + RTL+NT
Sbjct: 92 MGRTLQNT 99



>NP_001017975
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LARTLKNT 8
           +++TLKNT
Sbjct: 438 VSQTLKNT 445



>NP_002853
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LARTLKNT 8
          + RTL+NT
Sbjct: 92 MGRTLQNT 99



>XP_006723664
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LARTLKNT 8
          + RTL+NT
Sbjct: 92 MGRTLQNT 99



>XP_005275805
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  RTLKNTQ 9
          RTL NTQ
Sbjct: 39 RTLGNTQ 45



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.119    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 373,338
Number of extensions: 537
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)