Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001273479                                                           17    2528
NP_997292                                                              17    2528
NP_001171601                                                           17    3301
NP_001954                                                              17    3301
NP_001171602                                                           17    3301
XP_005262857                                                           17    3301
XP_005262856                                                           17    3301
XP_006714188                                                           17    3301
XP_006714187                                                           17    3301
XP_005262855                                                           17    3301
XP_005262854                                                           17    3301
XP_005262853                                                           17    3301
NP_001135758                                                           17    4312
NP_078900                                                              17    4312
NP_060634                                                              17    4312
XP_006719170                                                           17    4312
XP_005253479                                                           17    4312
XP_006719169                                                           17    4312
XP_005262685                                                           17    4312
NP_001193865                                                           16    5631
NP_001193895                                                           16    5631
NP_001193858                                                           16    5631
NP_001193869                                                           16    5631
NP_001193861                                                           16    5631
NP_001193883                                                           16    5631
NP_001193863                                                           16    5631
NP_001127                                                              16    5631
NP_751947                                                              16    5631
NP_000632                                                              16    5631
NP_036525                                                              16    5631
NP_061720                                                              16    5631
NP_443187                                                              16    5631
NP_001008844                                                           16    7355
NP_004406                                                              16    7355
NP_004791                                                              16    7355
NP_055671                                                              16    7355
NP_001077422                                                           16    7355
NP_071348                                                              16    7355
NP_112598                                                              16    7355
NP_001245240                                                           16    7355
XP_006712132                                                           16    7355
XP_006712130                                                           16    7355
XP_006712129                                                           16    7355
XP_006712128                                                           16    7355
XP_006712127                                                           16    7355
XP_006712126                                                           16    7355
XP_006712125                                                           16    7355
XP_006712124                                                           16    7355
XP_005245736                                                           16    7355
XP_005245735                                                           16    7355
XP_006711753                                                           16    7355
NP_002817                                                              15    9605
NP_001004128                                                           15    9605
NP_775837                                                              15    9605
NP_001275677                                                           15    9605
NP_996801                                                              15    9605
NP_473362                                                              15    9605
NP_060631                                                              15    9605
NP_001186257                                                           15    9605
NP_003829                                                              15    9605
NP_001041677                                                           15    9605
XP_006724284                                                           15    9605
XP_006724283                                                           15    9605
XP_006724282                                                           15    9605
XP_005261537                                                           15    9605
XP_005258567                                                           15    9605
XP_006720106                                                           15    9605
NP_789780                                                              15    9605
>NP_001273479
          Length = 153

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  AILSLWSA 9
          A+L LWSA
Sbjct: 15 AVLPLWSA 22
>NP_997292
          Length = 100

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  AILSLWSA 9
          A+L LWSA
Sbjct: 15 AVLPLWSA 22
>NP_001171601
          Length = 1166

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1005 LLLLSLWGA 1013
>NP_001954
          Length = 1207

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1046 LLLLSLWGA 1054
>NP_001171602
          Length = 1165

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1004 LLLLSLWGA 1012
>XP_005262857
          Length = 1052

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           L +LSLW A
Sbjct: 965 LLLLSLWGA 973
>XP_005262856
          Length = 1061

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1046 LLLLSLWGA 1054
>XP_006714188
          Length = 1132

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           L +LSLW A
Sbjct: 963 LLLLSLWGA 971
>XP_006714187
          Length = 1133

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1046 LLLLSLWGA 1054
>XP_005262855
          Length = 1134

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           L +LSLW A
Sbjct: 965 LLLLSLWGA 973
>XP_005262854
          Length = 1173

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1004 LLLLSLWGA 1012
>XP_005262853
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LAILSLWSA 9
            L +LSLW A
Sbjct: 1046 LLLLSLWGA 1054
>NP_001135758
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            ILSLWS
Sbjct: 1000 ILSLWS 1005
>NP_078900
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            ILSLWS
Sbjct: 1000 ILSLWS 1005
>NP_060634
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAILSLWS 8
           +++LSLWS
Sbjct: 651 VSLLSLWS 658
>XP_006719170
          Length = 631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAILSLWS 8
           +++LSLWS
Sbjct: 576 VSLLSLWS 583
>XP_005253479
          Length = 649

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAILSLWS 8
           +++LSLWS
Sbjct: 594 VSLLSLWS 601
>XP_006719169
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAILSLWS 8
           +++LSLWS
Sbjct: 651 VSLLSLWS 658
>XP_005262685
          Length = 1113

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            ILSLWS
Sbjct: 1022 ILSLWS 1027
>NP_001193865
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193895
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193858
          Length = 420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193869
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193861
          Length = 390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193883
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001193863
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_001127
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_751947
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ILSLWSA 9
          +LSLW A
Sbjct: 13 VLSLWGA 19
>NP_000632
          Length = 199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LAILSLW 7
          L +LSLW
Sbjct: 9  LVVLSLW 15
>NP_036525
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    AILSLWSA 9
            A+L +WSA
Sbjct: 1225 AVLPVWSA 1232
>NP_061720
          Length = 4024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LAILSLW 7
           LA+L LW
Sbjct: 279 LAVLDLW 285
>NP_443187
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           +AIL  WSA
Sbjct: 260 VAILQQWSA 268
>NP_001008844
          Length = 2272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AILSLWS 8
           AIL+LW+
Sbjct: 532 AILALWN 538
>NP_004406
          Length = 2871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AILSLWS 8
           AIL+LW+
Sbjct: 532 AILALWN 538
>NP_004791
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LAILSLW 7
           +AIL+LW
Sbjct: 471 VAILALW 477
>NP_055671
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           +A+LS W A
Sbjct: 318 IAVLSRWPA 326
>NP_001077422
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1522 LAIAAVWAA 1530
>NP_071348
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1522 LAIAAVWAA 1530
>NP_112598
          Length = 5088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    AILSLWSA 9
            A LSLW A
Sbjct: 1334 ASLSLWQA 1341
>NP_001245240
          Length = 524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   AILSLWS 8
           ++LS+WS
Sbjct: 184 SVLSIWS 190
>XP_006712132
          Length = 1136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LAILSLWSA 9
           LAI ++W+A
Sbjct: 705 LAIAAVWAA 713
>XP_006712130
          Length = 1831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1400 LAIAAVWAA 1408
>XP_006712129
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1401 LAIAAVWAA 1409
>XP_006712128
          Length = 1879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1448 LAIAAVWAA 1456
>XP_006712127
          Length = 1909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1522 LAIAAVWAA 1530
>XP_006712126
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1482 LAIAAVWAA 1490
>XP_006712125
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1521 LAIAAVWAA 1529
>XP_006712124
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LAILSLWSA 9
            LAI ++W+A
Sbjct: 1522 LAIAAVWAA 1530
>XP_005245736
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           +A+LS W A
Sbjct: 318 IAVLSRWPA 326
>XP_005245735
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           +A+LS W A
Sbjct: 329 IAVLSRWPA 337
>XP_006711753
          Length = 1521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAILSLWSA 9
           +A+LS W A
Sbjct: 343 IAVLSRWPA 351
>NP_002817
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AILSLWSA 9
           A+L LWS+
Sbjct: 473 AVLWLWSS 480
>NP_001004128
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AILSLWSA 9
           A+L LWS+
Sbjct: 473 AVLWLWSS 480
>NP_775837
          Length = 2151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            +LS+WS
Sbjct: 1884 VLSIWS 1889
>NP_001275677
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LAILSLW 7
           LA+LS W
Sbjct: 509 LAVLSWW 515
>NP_996801
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LAILSLW 7
           LAI +LW
Sbjct: 198 LAIFALW 204
>NP_473362
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   LAILSLW 7
           LA+L++W
Sbjct: 418 LAVLAVW 424
>NP_060631
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AILSLWS 8
           A LSLWS
Sbjct: 497 AQLSLWS 503
>NP_001186257
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LSLWSA 9
           LSLW+A
Sbjct: 279 LSLWTA 284
>NP_003829
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LSLWSA 9
           LSLW+A
Sbjct: 533 LSLWTA 538
>NP_001041677
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ILSLWS 8
           ILSLW+
Sbjct: 129 ILSLWT 134
>XP_006724284
          Length = 1989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            +LS+WS
Sbjct: 1722 VLSIWS 1727
>XP_006724283
          Length = 2151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            +LS+WS
Sbjct: 1884 VLSIWS 1889
>XP_006724282
          Length = 2151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            +LS+WS
Sbjct: 1884 VLSIWS 1889
>XP_005261537
          Length = 2151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    ILSLWS 8
            +LS+WS
Sbjct: 1884 VLSIWS 1889
>XP_005258567
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LAILSLWS 8
           LAI  LWS
Sbjct: 486 LAIEGLWS 493
>XP_006720106
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LAILSLW 7
           LAI +LW
Sbjct: 162 LAIFALW 168
>NP_789780
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LAILSLWS 8
           LAI  LWS
Sbjct: 486 LAIEGLWS 493
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.128    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 648,498
Number of extensions: 690
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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