Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001193988                                                           17    4312
NP_001193987                                                           17    4312
NP_006050                                                              17    4312
XP_003960150                                                           17    4312
XP_006720774                                                           17    4312
XP_006720773                                                           17    4312
XP_006720772                                                           17    4312
XP_006720771                                                           17    4312
XP_001721585                                                           17    4312
NP_001001331                                                           16    5631
NP_001123559                                                           16    5631
NP_001123558                                                           16    5631
NP_001123557                                                           16    5631
NP_001123556                                                           16    5631
NP_001674                                                              16    5631
NP_065928                                                              16    5631
NP_001273651                                                           16    5631
NP_055427                                                              16    5631
NP_001273652                                                           16    5631
XP_005256527                                                           16    5631
XP_005251899                                                           16    5631
XP_005248087                                                           16    5631
XP_006713990                                                           16    5631
XP_005248084                                                           16    5631
XP_006713989                                                           16    5631
XP_005248081                                                           16    5631
XP_005248080                                                           16    5631
XP_005248079                                                           16    5631
XP_006713988                                                           16    5631
XP_005248077                                                           16    5631
XP_006713987                                                           16    5631
XP_006713986                                                           16    5631
XP_006713984                                                           16    5631
XP_006713245                                                           16    5631
XP_006713244                                                           16    5631
XP_006713243                                                           16    5631
XP_006713242                                                           16    5631
XP_006713241                                                           16    5631
XP_006713240                                                           16    5631
XP_006713239                                                           16    5631
XP_005265236                                                           16    5631
XP_006713238                                                           16    5631
NP_115583                                                              16    7355
NP_001275763                                                           16    7355
NP_060009                                                              16    7355
XP_006722984                                                           16    7355
XP_006722983                                                           16    7355
XP_006721125                                                           16    7355
NP_699161                                                              15    9605
NP_001157865                                                           15    9605
NP_031384                                                              15    9605
NP_055855                                                              15    9605
NP_001424                                                              15    9605
NP_001157864                                                           15    9605
NP_001157863                                                           15    9605
NP_001008537                                                           15    9605
XP_006724709                                                           15    9605
XP_006724708                                                           15    9605
XP_006721832                                                           15    9605
XP_006713582                                                           15    9605
XP_006712426                                                           15    9605
XP_006712425                                                           15    9605
XP_006712424                                                           15    9605
>NP_001193988
          Length = 461

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 283 ADSKKKSN 290
>NP_001193987
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 322 ADSKKKSN 329
>NP_006050
          Length = 1575

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LADSRKKS 8
            LAD+RKK+
Sbjct: 1370 LADTRKKT 1377
>XP_003960150
          Length = 169

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           AD+R+KSS
Sbjct: 108 ADNRRKSS 115
>XP_006720774
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 261 ADSKKKSN 268
>XP_006720773
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 261 ADSKKKSN 268
>XP_006720772
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 261 ADSKKKSN 268
>XP_006720771
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           ADS+KKS+
Sbjct: 372 ADSKKKSN 379
>XP_001721585
          Length = 169

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ADSRKKSS 9
           AD+R+KSS
Sbjct: 108 ADNRRKSS 115
>NP_001001331
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>NP_001123559
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 415 DNRKKSS 421
>NP_001123558
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 404 DNRKKSS 410
>NP_001123557
          Length = 572

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 456 DNRKKSS 462
>NP_001123556
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 456 DNRKKSS 462
>NP_001674
          Length = 1198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 325 ADDRKKAS 332
>NP_065928
          Length = 4427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ADSRKKSS 9
            A+SRKKS+
Sbjct: 4368 AESRKKSA 4375
>NP_001273651
          Length = 1117

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           LA+SRKK+
Sbjct: 615 LAESRKKT 622
>NP_055427
          Length = 1118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           LA+SRKK+
Sbjct: 616 LAESRKKT 623
>NP_001273652
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           LA+SRKK+
Sbjct: 616 LAESRKKT 623
>XP_005256527
          Length = 4427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ADSRKKSS 9
            A+SRKKS+
Sbjct: 4368 AESRKKSA 4375
>XP_005251899
          Length = 1117

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           LA+SRKK+
Sbjct: 616 LAESRKKT 623
>XP_005248087
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 409 DNRKKSS 415
>XP_006713990
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 420 DNRKKSS 426
>XP_005248084
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 409 DNRKKSS 415
>XP_006713989
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 420 DNRKKSS 426
>XP_005248081
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 461 DNRKKSS 467
>XP_005248080
          Length = 610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 494 DNRKKSS 500
>XP_005248079
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 461 DNRKKSS 467
>XP_006713988
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 505 DNRKKSS 511
>XP_005248077
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 494 DNRKKSS 500
>XP_006713987
          Length = 660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 505 DNRKKSS 511
>XP_006713986
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 545 DNRKKSS 551
>XP_006713984
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSRKKSS 9
           D+RKKSS
Sbjct: 545 DNRKKSS 551
>XP_006713245
          Length = 1174

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 339 ADDRKKAS 346
>XP_006713244
          Length = 1198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 325 ADDRKKAS 332
>XP_006713243
          Length = 1199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>XP_006713242
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>XP_006713241
          Length = 1212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 339 ADDRKKAS 346
>XP_006713240
          Length = 1232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 359 ADDRKKAS 366
>XP_006713239
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>XP_005265236
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>XP_006713238
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           AD RKK+S
Sbjct: 370 ADDRKKAS 377
>NP_115583
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADSRKKS 8
           A+SRKKS
Sbjct: 513 AESRKKS 519
>NP_001275763
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADSRKKS 8
           A+SRKKS
Sbjct: 513 AESRKKS 519
>NP_060009
          Length = 4116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ADSRKK 7
            ADSRKK
Sbjct: 1969 ADSRKK 1974
>XP_006722984
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADSRKKS 8
           A+SRKKS
Sbjct: 159 AESRKKS 165
>XP_006722983
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADSRKKS 8
           A+SRKKS
Sbjct: 513 AESRKKS 519
>XP_006721125
          Length = 4070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ADSRKK 7
            ADSRKK
Sbjct: 1923 ADSRKK 1928
>NP_699161
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LADSRKKS 8
          L+DS+K+S
Sbjct: 56 LSDSKKRS 63
>NP_001157865
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           L+DSRK++
Sbjct: 374 LSDSRKRT 381
>NP_031384
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           L+DSRK++
Sbjct: 476 LSDSRKRT 483
>NP_055855
          Length = 2098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ADSRKKSS 9
            +DSR KSS
Sbjct: 1706 SDSRPKSS 1713
>NP_001424
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ADSRKKS 8
           ADS KKS
Sbjct: 393 ADSEKKS 399
>NP_001157864
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           L+DSRK++
Sbjct: 419 LSDSRKRT 426
>NP_001157863
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LADSRKKS 8
           L+DSRK++
Sbjct: 374 LSDSRKRT 381
>NP_001008537
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LADSRKKSS 9
            ++ SRKKSS
Sbjct: 1172 VSKSRKKSS 1180
>XP_006724709
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LADSRKKSS 9
            ++ SRKKSS
Sbjct: 1172 VSKSRKKSS 1180
>XP_006724708
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LADSRKKSS 9
            ++ SRKKSS
Sbjct: 1172 VSKSRKKSS 1180
>XP_006721832
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ADSRKKS 8
           ADS KKS
Sbjct: 508 ADSEKKS 514
>XP_006713582
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LADSRKKS 8
          L+DS+K+S
Sbjct: 56 LSDSKKRS 63
>XP_006712426
          Length = 1237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ADSRKKSS 9
            +DSR KSS
Sbjct: 1012 SDSRPKSS 1019
>XP_006712425
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ADSRKKSS 9
            +DSR KSS
Sbjct: 1012 SDSRPKSS 1019
>XP_006712424
          Length = 1376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADSRKKSS 9
           +DSR KSS
Sbjct: 984 SDSRPKSS 991
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.104    0.232 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,891
Number of extensions: 708
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package