Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004786                                                              18    1482
NP_006197                                                              18    1935
XP_005265800                                                           18    1935
XP_006714103                                                           18    1935
XP_006714102                                                           18    1935
NP_783864                                                              17    3301
XP_005262701                                                           17    3301
NP_001010938                                                           17    4312
NP_005772                                                              17    4312
XP_006713531                                                           17    4312
XP_005269331                                                           17    4312
XP_005269330                                                           17    4312
XP_005269329                                                           17    4312
XP_005269328                                                           17    4312
XP_005269327                                                           17    4312
XP_006713530                                                           17    4312
XP_006713529                                                           17    4312
XP_005269326                                                           17    4312
XP_006713528                                                           17    4312
XP_006713527                                                           17    4312
XP_005269325                                                           17    4312
XP_006713526                                                           17    4312
XP_006713525                                                           17    4312
XP_006713524                                                           17    4312
XP_006713523                                                           17    4312
NP_002011                                                              16    5631
NP_891555                                                              16    5631
NP_001070                                                              16    5631
NP_065681                                                              16    5631
NP_066124                                                              16    5631
NP_997402                                                              16    5631
NP_001167639                                                           16    5631
NP_001167638                                                           16    5631
NP_001128524                                                           16    5631
NP_003168                                                              16    5631
NP_002244                                                              16    5631
NP_001973                                                              16    5631
NP_061935                                                              16    5631
NP_002010                                                              16    5631
NP_003322                                                              16    5631
NP_055897                                                              16    5631
XP_006717999                                                           16    5631
XP_005252204                                                           16    5631
XP_006712792                                                           16    5631
XP_006712791                                                           16    5631
XP_005264072                                                           16    5631
NP_006840                                                              16    5631
NP_000213                                                              16    7355
NP_001087241                                                           16    7355
NP_001156909                                                           16    7355
NP_001156908                                                           16    7355
NP_001156907                                                           16    7355
XP_006714482                                                           16    7355
XP_005265799                                                           16    7355
XP_005265798                                                           16    7355
XP_005265797                                                           16    7355
NP_004374                                                              15    9605
NP_001120662                                                           15    9605
NP_940980                                                              15    9605
NP_002600                                                              15    9605
NP_116164                                                              15    9605
NP_057062                                                              15    9605
NP_057111                                                              15    9605
NP_001007562                                                           15    9605
NP_001106279                                                           15    9605
NP_001186256                                                           15    9605
XP_006724406                                                           15    9605
XP_006724405                                                           15    9605
XP_005258573                                                           15    9605
XP_005258572                                                           15    9605
XP_005254222                                                           15    9605
XP_005268686                                                           15    9605
XP_005268521                                                           15    9605
>NP_004786
          Length = 1012

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           L AHN+LLA
Sbjct: 266 LVAHNLLLA 274
>NP_006197
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVLLA
Sbjct: 819 LAARNVLLA 827
>XP_005265800
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVLLA
Sbjct: 819 LAARNVLLA 827
>XP_006714103
          Length = 1111

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVLLA
Sbjct: 841 LAARNVLLA 849
>XP_006714102
          Length = 1114

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVLLA
Sbjct: 844 LAARNVLLA 852
>NP_783864
          Length = 1044

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AAHNVLLA 9
           AAHN+L+A
Sbjct: 711 AAHNLLVA 718
>XP_005262701
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AAHNVLLA 9
           AAHN+L+A
Sbjct: 702 AAHNLLVA 709
>NP_001010938
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 316 LAARNLLLA 324
>NP_005772
          Length = 1038

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 253 LAARNLLLA 261
>XP_006713531
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_005269331
          Length = 816

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LAAHNVLLA 9
          LAA N+LLA
Sbjct: 14 LAARNLLLA 22
>XP_005269330
          Length = 979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 177 LAARNLLLA 185
>XP_005269329
          Length = 1040

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 285 LAARNLLLA 293
>XP_005269328
          Length = 1055

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 253 LAARNLLLA 261
>XP_005269327
          Length = 1055

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 253 LAARNLLLA 261
>XP_006713530
          Length = 1063

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 261 LAARNLLLA 269
>XP_006713529
          Length = 1085

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_005269326
          Length = 1087

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 285 LAARNLLLA 293
>XP_006713528
          Length = 1101

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_006713527
          Length = 1115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_005269325
          Length = 1118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 316 LAARNLLLA 324
>XP_006713526
          Length = 1118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_006713525
          Length = 1119

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 317 LAARNLLLA 325
>XP_006713524
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>XP_006713523
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+LLA
Sbjct: 331 LAARNLLLA 339
>NP_002011
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LAAHNVLLA 9
            LAA N+LL+
Sbjct: 1038 LAARNILLS 1046
>NP_891555
          Length = 1363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LAAHNVLLA 9
            LAA N+LL+
Sbjct: 1038 LAARNILLS 1046
>NP_001070
          Length = 619

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 462 LAARNVLL 469
>NP_065681
          Length = 1072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+L+A
Sbjct: 875 LAARNILVA 883
>NP_066124
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+L+A
Sbjct: 875 LAARNILVA 883
>NP_997402
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 155 LAARNVLL 162
>NP_001167639
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 472 LAARNVLL 479
>NP_001167638
          Length = 635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 495 LAARNVLL 502
>NP_001128524
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 472 LAARNVLL 479
>NP_003168
          Length = 635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 495 LAARNVLL 502
>NP_002244
          Length = 1356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LAAHNVLLA 9
            LAA N+LL+
Sbjct: 1029 LAARNILLS 1037
>NP_001973
          Length = 1342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 835 LAARNVLL 842
>NP_061935
          Length = 227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAAH +LLA
Sbjct: 155 LAAHLLLLA 163
>NP_002010
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LAAHNVLLA 9
            LAA N+LL+
Sbjct: 1023 LAARNILLS 1031
>NP_003322
          Length = 1187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LAAHNVLL 8
            LAA NVLL
Sbjct: 1024 LAARNVLL 1031
>NP_055897
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LAAHNVLLA 9
          L++HN LLA
Sbjct: 55 LSSHNELLA 63
>XP_006717999
          Length = 1207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA N+L+A
Sbjct: 968 LAARNILVA 976
>XP_005252204
          Length = 635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 495 LAARNVLL 502
>XP_006712792
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 155 LAARNVLL 162
>XP_006712791
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 462 LAARNVLL 469
>XP_005264072
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVLL
Sbjct: 456 LAARNVLL 463
>NP_006840
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LAAHNVLLA 9
           LAAH  LLA
Sbjct: 287 LAAHRELLA 295
>NP_000213
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA N+LL
Sbjct: 793 LAARNILL 800
>NP_001087241
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA N+LL
Sbjct: 789 LAARNILL 796
>NP_001156909
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L+ HN+LL
Sbjct: 117 LSPHNILL 124
>NP_001156908
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L+ HN+LL
Sbjct: 117 LSPHNILL 124
>NP_001156907
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L+ HN+LL
Sbjct: 117 LSPHNILL 124
>XP_006714482
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L+ HN+LL
Sbjct: 117 LSPHNILL 124
>XP_005265799
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA N+LL
Sbjct: 790 LAARNILL 797
>XP_005265798
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA N+LL
Sbjct: 793 LAARNILL 800
>XP_005265797
          Length = 977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA N+LL
Sbjct: 794 LAARNILL 801
>NP_004374
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVL++
Sbjct: 315 LAARNVLVS 323
>NP_001120662
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVL++
Sbjct: 315 LAARNVLVS 323
>NP_940980
          Length = 2527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LAAHNVLL 8
            L  HNVLL
Sbjct: 1995 LKPHNVLL 2002
>NP_002600
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVL+
Sbjct: 827 LAARNVLI 834
>NP_116164
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LAAHNVLLA 9
          + AH +LLA
Sbjct: 61 IEAHRILLA 69
>NP_057062
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L +HN+LL
Sbjct: 589 LNSHNILL 596
>NP_057111
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           +A HN+LL
Sbjct: 256 MAKHNLLL 263
>NP_001007562
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AAHNVLL 8
           AAH VLL
Sbjct: 596 AAHGVLL 602
>NP_001106279
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L +HN+LL
Sbjct: 703 LNSHNILL 710
>NP_001186256
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           L +HN+LL
Sbjct: 703 LNSHNILL 710
>XP_006724406
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAAHNVLLA 9
           + AH +LLA
Sbjct: 93  IEAHRILLA 101
>XP_006724405
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LAAHNVLLA 9
           + AH +LLA
Sbjct: 109 IEAHRILLA 117
>XP_005258573
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AAHNVLL 8
           AAH VLL
Sbjct: 596 AAHGVLL 602
>XP_005258572
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AAHNVLL 8
           AAH VLL
Sbjct: 596 AAHGVLL 602
>XP_005254222
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAAHNVLLA 9
           LAA NVL++
Sbjct: 315 LAARNVLVS 323
>XP_005268686
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LAAHNVLL 8
            L  HNVLL
Sbjct: 1995 LKPHNVLL 2002
>XP_005268521
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAAHNVLL 8
           LAA NVL+
Sbjct: 763 LAARNVLI 770
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.132    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 474,763
Number of extensions: 613
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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