Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_116195                                                              19     869
XP_006713424                                                           19     869
XP_005265572                                                           19     869
NP_001013433                                                           18    1135
NP_060785                                                              18    1135
NP_361014                                                              18    1135
NP_061182                                                              17    2528
NP_001123509                                                           17    2528
NP_057306                                                              17    3301
XP_006714933                                                           17    3301
NP_006284                                                              17    4312
NP_775882                                                              16    7355
NP_001138871                                                           16    7355
NP_683692                                                              16    7355
NP_001120650                                                           16    7355
NP_001275980                                                           16    7355
NP_001037835                                                           16    7355
NP_001008781                                                           16    7355
NP_001575                                                              16    7355
NP_060203                                                              16    7355
NP_001275982                                                           16    7355
NP_001275981                                                           16    7355
NP_005217                                                              16    7355
XP_006718827                                                           16    7355
XP_006718368                                                           16    7355
XP_005253171                                                           16    7355
XP_005253170                                                           16    7355
XP_006718367                                                           16    7355
XP_005253169                                                           16    7355
XP_005253168                                                           16    7355
XP_005253167                                                           16    7355
XP_006714215                                                           16    7355
XP_006714214                                                           16    7355
XP_005262915                                                           16    7355
XP_005248208                                                           16    7355
XP_005248207                                                           16    7355
XP_006714021                                                           16    7355
XP_005272346                                                           16    7355
XP_005272345                                                           16    7355
XP_005272344                                                           16    7355
XP_006713955                                                           16    7355
XP_005272341                                                           16    7355
XP_005272340                                                           16    7355
NP_055806                                                              16    7355
NP_976328                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_596870                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_005305                                                              15    9605
NP_001099001                                                           15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
NP_001819                                                              15    9605
XP_006726852                                                           15    9605
XP_006723594                                                           15    9605
XP_005248807                                                           15    9605
XP_005248805                                                           15    9605
XP_005248804                                                           15    9605
XP_005248803                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_006710109                                                           15    9605
NP_001254479                                                           15    9605
NP_001004474                                                           15    9605
NP_597681                                                              15    9605
>NP_116195
          Length = 580

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 254 KANILVSGN 262
>XP_006713424
          Length = 580

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 254 KANILVSGN 262
>XP_005265572
          Length = 580

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 254 KANILVSGN 262
>NP_001013433
          Length = 589

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 472 KDNILVSGN 480
>NP_060785
          Length = 627

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 510 KDNILVSGN 518
>NP_361014
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           K NILVSGN
Sbjct: 590 KDNILVSGN 598
>NP_061182
          Length = 334

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YNILVSG 8
           YN+LVSG
Sbjct: 248 YNLLVSG 254
>NP_001123509
          Length = 326

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YNILVSG 8
           YN+LVSG
Sbjct: 240 YNLLVSG 246
>NP_057306
          Length = 622

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           KY+ILV G+
Sbjct: 166 KYHILVEGD 174
>XP_006714933
          Length = 496

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KYNILVSGN 9
          KY+ILV G+
Sbjct: 40 KYHILVEGD 48
>NP_006284
          Length = 890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YNILVSGN 9
           YN L+ GN
Sbjct: 742 YNYLIGGN 749
>NP_775882
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   YNILVSGN 9
           Y++L+SG+
Sbjct: 95  YSVLISGD 102
>NP_001138871
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>NP_683692
          Length = 3051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    YNILVSG 8
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>NP_001120650
          Length = 983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 528 NVLVGGN 534
>NP_001275980
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 439 NVLVGGN 445
>NP_001037835
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 141 EYKIVIAGN 149
>NP_001008781
          Length = 4557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KYNILVSGN 9
            KY+IL  GN
Sbjct: 2016 KYSILNPGN 2024
>NP_001575
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>NP_060203
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 520 NVLVGGN 526
>NP_001275982
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 439 NVLVGGN 445
>NP_001275981
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 395 NVLVGGN 401
>NP_005217
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KYNILVSG 8
           K NIL+SG
Sbjct: 93  KVNILMSG 100
>XP_006718827
          Length = 3479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KYNILVSGN 9
           KY+IL  GN
Sbjct: 906 KYSILNPGN 914
>XP_006718368
          Length = 178

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>XP_005253171
          Length = 182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>XP_005253170
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KYNILVSGN 9
          +Y I+++GN
Sbjct: 11 EYKIVIAGN 19
>XP_006718367
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KYNILVSGN 9
          +Y I+++GN
Sbjct: 35 EYKIVIAGN 43
>XP_005253169
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>XP_005253168
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>XP_005253167
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KYNILVSGN 9
           +Y I+++GN
Sbjct: 109 EYKIVIAGN 117
>XP_006714215
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    YNILVSGN 9
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_006714214
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    YNILVSGN 9
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_005262915
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    YNILVSGN 9
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_005248208
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    YNILVSG 8
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_005248207
          Length = 3098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    YNILVSG 8
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_006714021
          Length = 3112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    YNILVSG 8
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_005272346
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_005272345
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_005272344
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_006713955
          Length = 861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 406 NVLVGGN 412
>XP_005272341
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 439 NVLVGGN 445
>XP_005272340
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILVSGN 9
           N+LV GN
Sbjct: 458 NVLVGGN 464
>NP_055806
          Length = 3526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    YNILVSGN 9
            Y+I+VSG+
Sbjct: 3139 YHIIVSGS 3146
>NP_976328
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   YNILVSGN 9
           +N+L+SG+
Sbjct: 718 FNVLLSGS 725
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3080 KYTVVAGGN 3088
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3080 KYTVVAGGN 3088
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3126 KYTVVAGGN 3134
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3126 KYTVVAGGN 3134
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3126 KYTVVAGGN 3134
>NP_005305
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YNILVSGN 9
           YN+ V GN
Sbjct: 242 YNLPVEGN 249
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 547 EYHVVVSGD 555
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 530 EYHVVVSGD 538
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 743 EYHVVVSGD 751
>NP_001819
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KYNILVSG 8
           KY ++V+G
Sbjct: 99  KYQVMVNG 106
>XP_006726852
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  YNILVSGN 9
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>XP_006723594
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  YNILVSGN 9
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>XP_005248807
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 410 EYHVVVSGD 418
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 573 EYHVVVSGD 581
>XP_005248804
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 606 EYHVVVSGD 614
>XP_005248803
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 683 EYHVVVSGD 691
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 743 EYHVVVSGD 751
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 769 EYHVVVSGD 777
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   KYNILVSGN 9
           +Y+++VSG+
Sbjct: 769 EYHVVVSGD 777
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3127 KYTVVAGGN 3135
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3127 KYTVVAGGN 3135
>XP_006710109
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  YNILVSGN 9
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3126 KYTVVAGGN 3134
>NP_001004474
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  YNILVSGN 9
          Y+I V+GN
Sbjct: 48 YSITVAGN 55
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    KYNILVSGN 9
            KY ++  GN
Sbjct: 3080 KYTVVAGGN 3088
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.136    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 512,473
Number of extensions: 902
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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