Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060719                                                              18    1935
NP_001258968                                                           18    1935
NP_001011649                                                           18    1935
NP_001185761                                                           18    1935
NP_071754                                                              18    1935
NP_001185763                                                           18    1935
NP_001002810                                                           18    1935
NP_055459                                                              18    1935
NP_001182189                                                           18    1935
NP_001002812                                                           18    1935
NP_001182190                                                           18    1935
XP_006717248                                                           18    1935
XP_006717247                                                           18    1935
XP_006717246                                                           18    1935
XP_006717245                                                           18    1935
XP_006717244                                                           18    1935
XP_006717243                                                           18    1935
XP_006717242                                                           18    1935
XP_006711719                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
NP_060627                                                              16    7355
NP_694580                                                              16    7355
NP_808592                                                              16    7355
NP_004306                                                              16    7355
NP_065801                                                              16    7355
XP_005269056                                                           16    7355
XP_005269055                                                           16    7355
XP_005273561                                                           16    7355
NP_001136245                                                           15    9605
NP_001136239                                                           15    9605
NP_001136236                                                           15    9605
NP_001136244                                                           15    9605
NP_001136238                                                           15    9605
NP_001136240                                                           15    9605
NP_001136243                                                           15    9605
NP_001136242                                                           15    9605
NP_001136235                                                           15    9605
NP_001136237                                                           15    9605
NP_001136241                                                           15    9605
NP_149045                                                              15    9605
NP_853553                                                              15    9605
XP_006718013                                                           15    9605
XP_005264449                                                           15    9605
>NP_060719
          Length = 1893

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>NP_001258968
          Length = 1663

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>NP_001011649
          Length = 1814

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>NP_071754
          Length = 310

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 189 KVEVESLKR 197
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>NP_001002810
          Length = 173

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>NP_001182189
          Length = 141

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 20 KVEVESLKR 28
>NP_001002812
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>NP_001182190
          Length = 176

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 55 KVEVESLKR 63
>XP_006717248
          Length = 1664

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>XP_006717247
          Length = 1670

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>XP_006717246
          Length = 1820

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>XP_006717245
          Length = 1861

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>XP_006717244
          Length = 1867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 107 KVEVESLKR 115
>XP_006717243
          Length = 1889

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 97  KVEVESLKR 105
>XP_006717242
          Length = 1898

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 106 KVEVESLKR 114
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 52 KVEVESLKR 60
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  KVVVESLKR 9
          KV VESLKR
Sbjct: 55 KVEVESLKR 63
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           KV VESLKR
Sbjct: 118 KVEVESLKR 126
>NP_060627
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVVESLK 8
           V+VESLK
Sbjct: 113 VIVESLK 119
>NP_694580
          Length = 208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VVVESLKR 9
          VVVE +KR
Sbjct: 37 VVVEDIKR 44
>NP_808592
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVVVESLK 8
          KV+V SLK
Sbjct: 74 KVIVNSLK 81
>NP_004306
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVVVESLK 8
          KV+V SLK
Sbjct: 90 KVIVNSLK 97
>NP_065801
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVVVESLKR 9
           ++VVE +KR
Sbjct: 118 RIVVEMIKR 126
>XP_005269056
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVVESLK 8
           V+VESLK
Sbjct: 113 VIVESLK 119
>XP_005269055
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVVESLK 8
           V+VESLK
Sbjct: 113 VIVESLK 119
>XP_005273561
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVVVESLK 8
          KV+V SLK
Sbjct: 52 KVIVNSLK 59
>NP_001136245
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1261 KVVVESI 1267
>NP_001136239
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1246 KVVVESI 1252
>NP_001136236
          Length = 1957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>NP_001136244
          Length = 1677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>NP_001136238
          Length = 1952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>NP_001136240
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1261 KVVVESI 1267
>NP_001136243
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1288 KVVVESI 1294
>NP_001136242
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>NP_001136235
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1288 KVVVESI 1294
>NP_001136237
          Length = 1886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1212 KVVVESI 1218
>NP_001136241
          Length = 1790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1295 KVVVESI 1301
>NP_149045
          Length = 1955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>NP_853553
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVESLKR 9
           +VESLKR
Sbjct: 138 LVESLKR 144
>XP_006718013
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVVVESL 7
            KVVVES+
Sbjct: 1283 KVVVESI 1289
>XP_005264449
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVESLKR 9
           +VESLKR
Sbjct: 195 LVESLKR 201
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.130    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 264,199
Number of extensions: 408
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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