Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     509
NP_001185763                                                           20     509
NP_055459                                                              20     509
XP_006726410                                                           20     509
XP_006711719                                                           20     509
XP_006711718                                                           20     509
XP_006711717                                                           20     509
XP_006711716                                                           20     509
XP_006711715                                                           20     509
XP_006711714                                                           20     509
XP_006711713                                                           20     509
XP_006711712                                                           20     509
XP_006711711                                                           20     509
XP_006711710                                                           20     509
XP_006711709                                                           20     509
XP_005277503                                                           20     509
XP_005273038                                                           20     509
XP_006711708                                                           20     509
XP_005277500                                                           20     509
XP_006711707                                                           20     509
XP_005277499                                                           20     509
XP_006711706                                                           20     509
XP_006711705                                                           20     509
XP_006711164                                                           20     509
XP_006710143                                                           20     509
XP_006710142                                                           20     509
XP_006710141                                                           20     509
NP_057726                                                              17    4312
NP_001234926                                                           17    4312
NP_002947                                                              17    4312
NP_937883                                                              17    4312
XP_005254495                                                           17    4312
XP_006719618                                                           17    4312
XP_006719617                                                           17    4312
XP_006719616                                                           17    4312
XP_006719615                                                           17    4312
XP_006719614                                                           17    4312
XP_005253652                                                           17    4312
XP_005253651                                                           17    4312
XP_005253650                                                           17    4312
NP_001074419                                                           16    7355
NP_001074248                                                           16    7355
NP_203693                                                              16    7355
NP_073590                                                              16    7355
NP_001243050                                                           16    7355
NP_006659                                                              16    7355
XP_005256712                                                           16    7355
XP_005267331                                                           16    7355
XP_006710883                                                           16    7355
XP_006710882                                                           16    7355
XP_006710881                                                           16    7355
NP_002213                                                              15    9605
NP_001093422                                                           15    9605
NP_001161744                                                           15    9605
NP_005106                                                              15    9605
NP_059447                                                              15    9605
NP_001035858                                                           15    9605
NP_057206                                                              15    9605
NP_002214                                                              15    9605
NP_060687                                                              15    9605
XP_005268999                                                           15    9605
XP_006719500                                                           15    9605
XP_006719127                                                           15    9605
XP_006713199                                                           15    9605
XP_006713198                                                           15    9605
XP_006713197                                                           15    9605
XP_005265167                                                           15    9605
XP_006713196                                                           15    9605
XP_006713195                                                           15    9605
XP_005265166                                                           15    9605
XP_006713194                                                           15    9605
NP_001138497                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1534 KVIEVLQAK 1542
>NP_001185763
          Length = 2362

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1578 KVIEVLQAK 1586
>NP_055459
          Length = 2346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1578 KVIEVLQAK 1586
>XP_006726410
          Length = 2087

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1381 KVIEVLQAK 1389
>XP_006711719
          Length = 2302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1534 KVIEVLQAK 1542
>XP_006711718
          Length = 1436

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           KV+EVLQAK
Sbjct: 585 KVIEVLQAK 593
>XP_006711717
          Length = 2385

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1534 KVIEVLQAK 1542
>XP_006711716
          Length = 2411

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1643 KVIEVLQAK 1651
>XP_006711715
          Length = 2428

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1577 KVIEVLQAK 1585
>XP_006711714
          Length = 2429

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1578 KVIEVLQAK 1586
>XP_006711713
          Length = 2432

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1581 KVIEVLQAK 1589
>XP_006711712
          Length = 2473

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_006711711
          Length = 2482

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1631 KVIEVLQAK 1639
>XP_006711710
          Length = 2494

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1643 KVIEVLQAK 1651
>XP_006711709
          Length = 2495

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1644 KVIEVLQAK 1652
>XP_005277503
          Length = 2498

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_005273038
          Length = 2509

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_006711708
          Length = 2512

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_005277500
          Length = 2525

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_006711707
          Length = 2553

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_005277499
          Length = 2561

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_006711706
          Length = 2591

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1740 KVIEVLQAK 1748
>XP_006711705
          Length = 2592

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1741 KVIEVLQAK 1749
>XP_006711164
          Length = 2087

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KVVEVLQAK 9
            KV+EVLQAK
Sbjct: 1381 KVIEVLQAK 1389
>XP_006710143
          Length = 562

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           KV+EVLQAK
Sbjct: 420 KVIEVLQAK 428
>XP_006710142
          Length = 671

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           KV+EVLQAK
Sbjct: 529 KVIEVLQAK 537
>XP_006710141
          Length = 672

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           KV+EVLQAK
Sbjct: 530 KVIEVLQAK 538
>NP_057726
          Length = 3674

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVLQAK
Sbjct: 607 VEVLQAK 613
>NP_001234926
          Length = 1438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>NP_002947
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 732 KELEVLQAK 740
>NP_937883
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 697 KELEVLQAK 705
>XP_005254495
          Length = 3694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVLQAK
Sbjct: 627 VEVLQAK 633
>XP_006719618
          Length = 1394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 697 KELEVLQAK 705
>XP_006719617
          Length = 1401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>XP_006719616
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 708 KELEVLQAK 716
>XP_006719615
          Length = 1429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 732 KELEVLQAK 740
>XP_006719614
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>XP_005253652
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>XP_005253651
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>XP_005253650
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KVVEVLQAK 9
           K +EVLQAK
Sbjct: 743 KELEVLQAK 751
>NP_001074419
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           ++VE+LQ+K
Sbjct: 591 QLVEILQSK 599
>NP_001074248
          Length = 1063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           ++VE+LQ+K
Sbjct: 610 QLVEILQSK 618
>NP_203693
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           ++VE+LQ+K
Sbjct: 575 QLVEILQSK 583
>NP_073590
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVVEVLQAK 9
           KV+ VLQ K
Sbjct: 297 KVIPVLQTK 305
>NP_001243050
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVVEVLQAK 9
           KV+ VLQ K
Sbjct: 297 KVIPVLQTK 305
>NP_006659
          Length = 500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           ++VE+L+AK
Sbjct: 163 QLVEILEAK 171
>XP_005256712
          Length = 1039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KVVEVLQAK 9
           ++VE+LQ+K
Sbjct: 586 QLVEILQSK 594
>XP_005267331
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  KVVEVLQAK 9
          ++VE+L+AK
Sbjct: 18 QLVEILEAK 26
>XP_006710883
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVVEVLQAK 9
           KV+ VLQ K
Sbjct: 297 KVIPVLQTK 305
>XP_006710882
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVVEVLQAK 9
           KV+ VLQ K
Sbjct: 297 KVIPVLQTK 305
>XP_006710881
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVVEVLQAK 9
           KV+ VLQ K
Sbjct: 296 KVIPVLQTK 304
>NP_002213
          Length = 2695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 959 KIIEILQ 965
>NP_001093422
          Length = 2710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 974 KIIEILQ 980
>NP_001161744
          Length = 2743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 968 KIIEILQ 974
>NP_005106
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVEVLQA 8
           +VVE++QA
Sbjct: 158 EVVEIIQA 165
>NP_059447
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVEVLQA 8
           +VVE++QA
Sbjct: 158 EVVEIIQA 165
>NP_001035858
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVL+AK
Sbjct: 585 VEVLEAK 591
>NP_057206
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVL+AK
Sbjct: 585 VEVLEAK 591
>NP_002214
          Length = 2701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 972 KIIEILQ 978
>NP_060687
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           +VVEVLQ
Sbjct: 96  RVVEVLQ 102
>XP_005268999
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVL+AK
Sbjct: 585 VEVLEAK 591
>XP_006719500
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VEVLQAK 9
           VEVL+AK
Sbjct: 585 VEVLEAK 591
>XP_006719127
          Length = 1865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 972 KIIEILQ 978
>XP_006713199
          Length = 2695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 983 KIIEILQ 989
>XP_006713198
          Length = 2699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 983 KIIEILQ 989
>XP_006713197
          Length = 2712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 959 KIIEILQ 965
>XP_005265167
          Length = 2719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 983 KIIEILQ 989
>XP_006713196
          Length = 2721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 968 KIIEILQ 974
>XP_006713195
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 974 KIIEILQ 980
>XP_005265166
          Length = 2735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 983 KIIEILQ 989
>XP_006713194
          Length = 2736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KVVEVLQ 7
           K++E+LQ
Sbjct: 983 KIIEILQ 989
>NP_001138497
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KVVEVLQ 7
          +VVEVLQ
Sbjct: 59 RVVEVLQ 65
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.126    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 266,426
Number of extensions: 484
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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