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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           18    1935
NP_004561                                                              18    1935
NP_061956                                                              18    1935
NP_001275703                                                           18    1935
XP_005253450                                                           18    1935
XP_006719151                                                           18    1935
XP_005271003                                                           18    1935
XP_005271002                                                           18    1935
NP_115495                                                              17    4312
NP_002464                                                              16    5631
NP_705838                                                              16    5631
NP_064627                                                              16    5631
NP_055227                                                              16    5631
NP_057063                                                              16    5631
NP_001139281                                                           16    5631
NP_001271183                                                           16    5631
NP_001271181                                                           16    5631
NP_001271180                                                           16    5631
NP_001070654                                                           16    5631
NP_004821                                                              16    5631
NP_113632                                                              16    5631
NP_079005                                                              16    5631
NP_001257451                                                           16    5631
NP_001257450                                                           16    5631
XP_006723449                                                           16    5631
XP_006715675                                                           16    5631
XP_005267280                                                           16    5631
XP_006713328                                                           16    5631
XP_006713327                                                           16    5631
XP_006713326                                                           16    5631
XP_006713325                                                           16    5631
XP_006713324                                                           16    5631
XP_005265385                                                           16    5631
NP_000920                                                              15    9605
NP_002058                                                              15    9605
NP_444251                                                              15    9605
NP_001183980                                                           15    9605
XP_006710759                                                           15    9605
XP_006710758                                                           15    9605
XP_005245953                                                           15    9605
XP_006710757                                                           15    9605
XP_006710756                                                           15    9605
XP_005245952                                                           15    9605
XP_006710755                                                           15    9605
XP_005245950                                                           15    9605
XP_005245949                                                           15    9605
XP_005245948                                                           15    9605
XP_006710754                                                           15    9605

>NP_001275701
          Length = 1486

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K LIEKVTT
Sbjct: 476 KGLIEKVTT 484



>NP_004561
          Length = 1445

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K LIEKVTT
Sbjct: 476 KGLIEKVTT 484



>NP_061956
          Length = 481

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLIEKVTT 9
           +L+EKVTT
Sbjct: 213 ILVEKVTT 220



>NP_001275703
          Length = 1264

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K LIEKVTT
Sbjct: 254 KGLIEKVTT 262



>XP_005253450
          Length = 1486

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K LIEKVTT
Sbjct: 476 KGLIEKVTT 484



>XP_006719151
          Length = 1486

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K LIEKVTT
Sbjct: 476 KGLIEKVTT 484



>XP_005271003
          Length = 340

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VLIEKVTT 9
          +L+EKVTT
Sbjct: 72 ILVEKVTT 79



>XP_005271002
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLIEKVTT 9
           +L+EKVTT
Sbjct: 199 ILVEKVTT 206



>NP_115495
          Length = 6306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LIEKVTT 9
            LIEK+TT
Sbjct: 5670 LIEKITT 5676



>NP_002464
          Length = 1960

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K+ +EKVTT
Sbjct: 961 KLQLEKVTT 969



>NP_705838
          Length = 4069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KVLIEKVTT 9
            KVL+EK  T
Sbjct: 2626 KVLVEKTKT 2634




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KVLIEKVTT 9
            KVL+EK  T
Sbjct: 2714 KVLVEKTKT 2722



>NP_064627
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 433 KSLIEKVT 440



>NP_055227
          Length = 228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          KVL+EK T
Sbjct: 14 KVLLEKAT 21



>NP_057063
          Length = 1365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>NP_001139281
          Length = 2036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVLIEKVTT 9
            K+ +EKVTT
Sbjct: 1026 KLQLEKVTT 1034



>NP_001271183
          Length = 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           KVL+EK T
Sbjct: 123 KVLVEKCT 130



>NP_001271181
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           KVL+EK T
Sbjct: 179 KVLVEKCT 186



>NP_001271180
          Length = 296

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           KVL+EK T
Sbjct: 179 KVLVEKCT 186



>NP_001070654
          Length = 2003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVLIEKVTT 9
            K+ +EKVTT
Sbjct: 993  KLQLEKVTT 1001



>NP_004821
          Length = 1368

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>NP_113632
          Length = 240

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           KVL+EK T
Sbjct: 123 KVLVEKCT 130



>NP_079005
          Length = 1995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           K+ +EKVTT
Sbjct: 985 KLQLEKVTT 993



>NP_001257451
          Length = 1364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>NP_001257450
          Length = 1359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>XP_006723449
          Length = 2003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVLIEKVTT 9
            K+ +EKVTT
Sbjct: 993  KLQLEKVTT 1001



>XP_006715675
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>XP_005267280
          Length = 1374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           KV++EK+ T
Sbjct: 139 KVILEKILT 147



>XP_006713328
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 433 KSLIEKVT 440



>XP_006713327
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K LIEKVT
Sbjct: 68 KSLIEKVT 75



>XP_006713326
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 433 KSLIEKVT 440



>XP_006713325
          Length = 1195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 433 KSLIEKVT 440



>XP_006713324
          Length = 1285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 433 KSLIEKVT 440



>XP_005265385
          Length = 1291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KVLIEKVT 8
           K LIEKVT
Sbjct: 336 KSLIEKVT 343



>NP_000920
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>NP_002058
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVLIEKVTT 9
           +V +EKVTT
Sbjct: 115 EVDVEKVTT 123



>NP_444251
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IEKVTT 9
           IEKVTT
Sbjct: 116 IEKVTT 121



>NP_001183980
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IEKVTT 9
           IEKVTT
Sbjct: 116 IEKVTT 121



>XP_006710759
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_006710758
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_005245953
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_006710757
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_006710756
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_005245952
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_006710755
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_005245950
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 26 KSMIEKVT 33



>XP_005245949
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 57 KSMIEKVT 64



>XP_005245948
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 57 KSMIEKVT 64



>XP_006710754
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KVLIEKVT 8
          K +IEKVT
Sbjct: 57 KSMIEKVT 64



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.129    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,428
Number of extensions: 517
Number of successful extensions: 49
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)