Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              20     390
XP_005271924                                                           20     390
XP_005271923                                                           20     390
NP_065101                                                              17    3301
NP_056288                                                              17    3301
NP_680481                                                              17    3301
NP_680480                                                              17    3301
XP_006724261                                                           17    3301
XP_005261505                                                           17    3301
XP_006724260                                                           17    3301
XP_005261504                                                           17    3301
NP_055152                                                              17    3301
NP_001264262                                                           17    4312
XP_003959998                                                           17    4312
NP_038202                                                              16    5631
NP_000622                                                              16    5631
NP_060021                                                              16    5631
NP_001258677                                                           16    5631
NP_055296                                                              16    5631
XP_006717867                                                           16    5631
NP_001165694                                                           16    7355
NP_443731                                                              16    7355
NP_570899                                                              16    7355
NP_067017                                                              16    7355
NP_056470                                                              16    7355
NP_001277190                                                           16    7355
NP_001019554                                                           16    7355
NP_060542                                                              16    7355
NP_001239202                                                           16    7355
NP_073751                                                              16    7355
NP_004104                                                              16    7355
NP_066360                                                              16    7355
NP_001239200                                                           16    7355
NP_055718                                                              16    7355
NP_001006606                                                           16    7355
NP_705833                                                              16    7355
NP_001239199                                                           16    7355
NP_001239198                                                           16    7355
XP_005274724                                                           16    7355
XP_005274723                                                           16    7355
XP_005274722                                                           16    7355
XP_006723622                                                           16    7355
XP_005260759                                                           16    7355
XP_006723621                                                           16    7355
XP_005258189                                                           16    7355
XP_006722402                                                           16    7355
XP_006719740                                                           16    7355
XP_006719739                                                           16    7355
XP_006719738                                                           16    7355
XP_005269272                                                           16    7355
XP_006718835                                                           16    7355
XP_005273858                                                           16    7355
XP_005273857                                                           16    7355
XP_006718834                                                           16    7355
XP_005273855                                                           16    7355
XP_006713602                                                           16    7355
XP_006713601                                                           16    7355
XP_005247284                                                           16    7355
XP_005247174                                                           16    7355
NP_005333                                                              16    7355
NP_787125                                                              15    9605
NP_689728                                                              15    9605
NP_001091995                                                           15    9605
NP_079040                                                              15    9605
NP_060674                                                              15    9605
NP_387467                                                              15    9605
XP_005266401                                                           15    9605
XP_005266400                                                           15    9605
XP_005269291                                                           15    9605
XP_006712229                                                           15    9605
NP_004106                                                              15    9605
NP_001273616                                                           15    9605
NP_001273615                                                           15    9605
>NP_001261
          Length = 1710

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVKSTKPQN 9
           KVKS KPQN
Sbjct: 187 KVKSRKPQN 195
>XP_005271924
          Length = 1710

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVKSTKPQN 9
           KVKS KPQN
Sbjct: 187 KVKSRKPQN 195
>XP_005271923
          Length = 1798

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVKSTKPQN 9
           KVKS KPQN
Sbjct: 187 KVKSRKPQN 195
>NP_065101
          Length = 479

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVKSTKPQ 8
           K KSTKP+
Sbjct: 340 KAKSTKPK 347
>NP_056288
          Length = 2046

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKSTKPQ 8
            VK+TKPQ
Sbjct: 1713 VKATKPQ 1719
>NP_680481
          Length = 527

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>NP_680480
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>XP_006724261
          Length = 342

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 282 KVKSSQPQ 289
>XP_005261505
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>XP_006724260
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>XP_005261504
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>NP_055152
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           KVKS++PQ
Sbjct: 460 KVKSSQPQ 467
>NP_001264262
          Length = 917

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           K+K+ KP N
Sbjct: 334 KIKNRKPDN 342
>XP_003959998
          Length = 639

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KVKSTKPQN 9
          K+K+ KP N
Sbjct: 56 KIKNRKPDN 64
>NP_038202
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KVKSTKPQ 8
           KVKS  PQ
Sbjct: 156 KVKSVSPQ 163
>NP_000622
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KVKSTKPQ 8
           KVKS  PQ
Sbjct: 156 KVKSVSPQ 163
>NP_060021
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KSTKPQN 9
           KSTKP N
Sbjct: 354 KSTKPWN 360
>NP_001258677
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 202 QVRSTRPQ 209
>NP_055296
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 373 QVRSTRPQ 380
>XP_006717867
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KSTKPQN 9
           KSTKP N
Sbjct: 354 KSTKPWN 360
>NP_001165694
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KVKSTKPQ 8
           KVK T PQ
Sbjct: 133 KVKCTAPQ 140
>NP_443731
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KVKSTKPQ 8
           KVK T PQ
Sbjct: 102 KVKCTAPQ 109
>NP_570899
          Length = 956

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 175 QVRSTQPQ 182
>NP_067017
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVKSTKP 7
           +VKST+P
Sbjct: 164 RVKSTRP 170
>NP_056470
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K KSTKP
Sbjct: 123 KEKSTKP 129
>NP_001277190
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K KSTKP
Sbjct: 123 KEKSTKP 129
>NP_001019554
          Length = 2385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1719 KKKSTKP 1725
>NP_060542
          Length = 2144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VKSTKP 7
           +KSTKP
Sbjct: 648 IKSTKP 653
>NP_001239202
          Length = 162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KVKSTKPQN 9
          K  STKP N
Sbjct: 90 KCLSTKPNN 98
>NP_073751
          Length = 472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  STKPQN 9
          STKP+N
Sbjct: 68 STKPEN 73
>NP_004104
          Length = 181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           +VK TKP +
Sbjct: 126 RVKKTKPSS 134
>NP_066360
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           +VK TKP +
Sbjct: 188 RVKKTKPSS 196
>NP_001239200
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KVKSTKPQN 9
          K  STKP N
Sbjct: 65 KCLSTKPNN 73
>NP_055718
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1719 KKKSTKP 1725
>NP_001006606
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KVKSTKPQN 9
          K  STKP N
Sbjct: 90 KCLSTKPNN 98
>NP_705833
          Length = 2970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            KVKS KP
Sbjct: 2738 KVKSLKP 2744
>NP_001239199
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KVKSTKPQN 9
          K  STKP N
Sbjct: 90 KCLSTKPNN 98
>NP_001239198
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  KVKSTKPQN 9
          K  STKP N
Sbjct: 45 KCLSTKPNN 53
>XP_005274724
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K+KST P
Sbjct: 110 KIKSTNP 116
>XP_005274723
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K+KST P
Sbjct: 130 KIKSTNP 136
>XP_005274722
          Length = 222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K+KST P
Sbjct: 132 KIKSTNP 138
>XP_006723622
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K KSTKP
Sbjct: 123 KEKSTKP 129
>XP_005260759
          Length = 719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  KVKSTKP 7
          K KSTKP
Sbjct: 91 KEKSTKP 97
>XP_006723621
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K KSTKP
Sbjct: 123 KEKSTKP 129
>XP_005258189
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  STKPQN 9
          STKP+N
Sbjct: 68 STKPEN 73
>XP_006722402
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  STKPQN 9
          STKP+N
Sbjct: 68 STKPEN 73
>XP_006719740
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1219 KKKSTKP 1225
>XP_006719739
          Length = 2306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1662 KKKSTKP 1668
>XP_006719738
          Length = 2340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1696 KKKSTKP 1702
>XP_005269272
          Length = 2356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            K KSTKP
Sbjct: 1712 KKKSTKP 1718
>XP_006718835
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 204 QVRSTQPQ 211
>XP_005273858
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVKSTKPQ 8
          +V+ST+PQ
Sbjct: 89 QVRSTQPQ 96
>XP_005273857
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 125 QVRSTQPQ 132
>XP_006718834
          Length = 978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 197 QVRSTQPQ 204
>XP_005273855
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVKSTKPQ 8
           +V+ST+PQ
Sbjct: 204 QVRSTQPQ 211
>XP_006713602
          Length = 157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           +VK TKP +
Sbjct: 102 RVKKTKPSS 110
>XP_006713601
          Length = 178

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           +VK TKP +
Sbjct: 123 RVKKTKPSS 131
>XP_005247284
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           +VK TKP +
Sbjct: 152 RVKKTKPSS 160
>XP_005247174
          Length = 2679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    KVKSTKP 7
            KVKS KP
Sbjct: 2447 KVKSLKP 2453
>NP_005333
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           K+KST P
Sbjct: 110 KIKSTNP 116
>NP_787125
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           +VK TKP
Sbjct: 191 RVKKTKP 197
>NP_689728
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KVKSTKPQ 8
           +VK TKP+
Sbjct: 327 RVKHTKPR 334
>NP_001091995
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 214 KATKPQ 219
>NP_079040
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KVKSTKPQN 9
           K+K T P+N
Sbjct: 984 KLKHTVPEN 992
>NP_060674
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 213 KATKPQ 218
>NP_387467
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VKSTKPQN 9
           + +TKP+N
Sbjct: 389 IHTTKPEN 396
>XP_005266401
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 166 KATKPQ 171
>XP_005266400
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 208 KATKPQ 213
>XP_005269291
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VKSTKPQN 9
           + +TKP+N
Sbjct: 389 IHTTKPEN 396
>XP_006712229
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KSTKPQN 9
           K+TKP N
Sbjct: 228 KATKPAN 234
>NP_004106
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KVKSTKP 7
           +VK TKP
Sbjct: 186 RVKKTKP 192
>NP_001273616
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 213 KATKPQ 218
>NP_001273615
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSTKPQ 8
           K+TKPQ
Sbjct: 165 KATKPQ 170
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.107    0.271 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 740,018
Number of extensions: 948
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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